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Gout

MedGen UID:
505046
Concept ID:
CN001808
Finding
Synonyms: Gouty arthritis
 

Definition

Recurrent attacks of acute inflammatory arthritis of a joint or set of joints caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues. [from HPO]

Recent clinical studies

Etiology

Min Z, Junwu M
Yi Chuan 2016 Apr;38(4):300-13. doi: 10.16288/j.yczz.15-385. PMID: 27103454
Burke BT, Köttgen A, Law A, Grams M, Baer AN, Coresh J, McAdams-DeMarco MA
J Gerontol A Biol Sci Med Sci 2016 Apr;71(4):536-42. Epub 2015 Dec 28 doi: 10.1093/gerona/glv120. [Epub ahead of print] PMID: 26714568
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Rheumatology (Oxford) 2016 Apr;55(4):721-8. Epub 2015 Dec 17 doi: 10.1093/rheumatology/kev418. [Epub ahead of print] PMID: 26683193
Lu N, Dubreuil M, Zhang Y, Neogi T, Rai SK, Ascherio A, Hernán MA, Choi HK
Ann Rheum Dis 2016 Mar;75(3):547-51. Epub 2015 Mar 4 doi: 10.1136/annrheumdis-2014-206917. [Epub ahead of print] PMID: 25739830Free PMC Article
Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, Onoue H, Iwaya K, Ito T, Takada T, Inoue K, Kato Y, Nakamura Y, Sakurai Y, Suzuki H, Kanai Y, Hosoya T, Hamajima N, Inoue I, Kubo M, Ichida K, Ooyama H, Shimizu T, Shinomiya N
Ann Rheum Dis 2016 Apr;75(4):652-9. Epub 2015 Feb 2 doi: 10.1136/annrheumdis-2014-206191. [Epub ahead of print] PMID: 25646370Free PMC Article

Diagnosis

Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Rheumatology (Oxford) 2016 Apr;55(4):721-8. Epub 2015 Dec 17 doi: 10.1093/rheumatology/kev418. [Epub ahead of print] PMID: 26683193
Doghramji PP, Fermer S, Wood R, Morlock R, Baumgartner S
Postgrad Med 2016 Jan;128(1):106-14. Epub 2015 Nov 23 doi: 10.1080/00325481.2016.1114878. [Epub ahead of print] PMID: 26592538
Khanna P, Khanna D, Storgard C, Baumgartner S, Morlock R
Postgrad Med 2016 Jan;128(1):34-40. Epub 2015 Nov 17 doi: 10.1080/00325481.2016.1113840. [Epub ahead of print] PMID: 26578028
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Ann Rheum Dis 2016 Jan;75(1):210-7. Epub 2014 Nov 14 doi: 10.1136/annrheumdis-2014-206410. [Epub ahead of print] PMID: 25398375Free PMC Article
Taylor WJ, Fransen J, Dalbeth N, Neogi T, Schumacher HR, Brown M, Louthrenoo W, Vazquez-Mellado J, Eliseev M, McCarthy G, Stamp LK, Perez-Ruiz F, Sivera F, Ea HK, Gerritsen M, Scire C, Cavagna L, Lin C, Chou YY, Tausche AK, da Rocha Castelar-Pinheiro G, Janssen M, Chen JH, Slot O, Cimmino M, Uhlig T, Jansen TL
Ann Rheum Dis 2016 Jan;75(1):178-82. Epub 2014 Oct 28 doi: 10.1136/annrheumdis-2014-206364. [Epub ahead of print] PMID: 25351521

Therapy

Doghramji PP, Fermer S, Wood R, Morlock R, Baumgartner S
Postgrad Med 2016 Jan;128(1):106-14. Epub 2015 Nov 23 doi: 10.1080/00325481.2016.1114878. [Epub ahead of print] PMID: 26592538
Khanna P, Khanna D, Storgard C, Baumgartner S, Morlock R
Postgrad Med 2016 Jan;128(1):34-40. Epub 2015 Nov 17 doi: 10.1080/00325481.2016.1113840. [Epub ahead of print] PMID: 26578028
Terslev L, Gutierrez M, Christensen R, Balint PV, Bruyn GA, Delle Sedie A, Filippucci E, Garrido J, Hammer HB, Iagnocco A, Kane D, Kaeley GS, Keen H, Mandl P, Naredo E, Pineda C, Schicke B, Thiele R, D'Agostino MA, Schmidt WA; OMERACT US Gout Task Force
J Rheumatol 2015 Nov;42(11):2149-54. Epub 2015 Oct 15 doi: 10.3899/jrheum.150366. [Epub ahead of print] PMID: 26472419
Becker MA, Fitz-Patrick D, Choi HK, Dalbeth N, Storgard C, Cravets M, Baumgartner S
Semin Arthritis Rheum 2015 Oct;45(2):174-83. Epub 2015 May 21 doi: 10.1016/j.semarthrit.2015.05.005. [Epub ahead of print] PMID: 26190562
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Rheumatology (Oxford) 2015 Dec;54(12):2145-50. Epub 2015 Jul 12 doi: 10.1093/rheumatology/kev246. [Epub ahead of print] PMID: 26170376

Prognosis

Burke BT, Köttgen A, Law A, Grams M, Baer AN, Coresh J, McAdams-DeMarco MA
J Gerontol A Biol Sci Med Sci 2016 Apr;71(4):536-42. Epub 2015 Dec 28 doi: 10.1093/gerona/glv120. [Epub ahead of print] PMID: 26714568
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Rheumatology (Oxford) 2016 Apr;55(4):721-8. Epub 2015 Dec 17 doi: 10.1093/rheumatology/kev418. [Epub ahead of print] PMID: 26683193
Khanna P, Khanna D, Storgard C, Baumgartner S, Morlock R
Postgrad Med 2016 Jan;128(1):34-40. Epub 2015 Nov 17 doi: 10.1080/00325481.2016.1113840. [Epub ahead of print] PMID: 26578028
Lu N, Dubreuil M, Zhang Y, Neogi T, Rai SK, Ascherio A, Hernán MA, Choi HK
Ann Rheum Dis 2016 Mar;75(3):547-51. Epub 2015 Mar 4 doi: 10.1136/annrheumdis-2014-206917. [Epub ahead of print] PMID: 25739830Free PMC Article
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Ann Rheum Dis 2016 Jan;75(1):210-7. Epub 2014 Nov 14 doi: 10.1136/annrheumdis-2014-206410. [Epub ahead of print] PMID: 25398375Free PMC Article

Clinical prediction guides

Burke BT, Köttgen A, Law A, Grams M, Baer AN, Coresh J, McAdams-DeMarco MA
J Gerontol A Biol Sci Med Sci 2016 Apr;71(4):536-42. Epub 2015 Dec 28 doi: 10.1093/gerona/glv120. [Epub ahead of print] PMID: 26714568
Khanna P, Khanna D, Storgard C, Baumgartner S, Morlock R
Postgrad Med 2016 Jan;128(1):34-40. Epub 2015 Nov 17 doi: 10.1080/00325481.2016.1113840. [Epub ahead of print] PMID: 26578028
Taylor WJ, Fransen J, Dalbeth N, Neogi T, Schumacher HR, Brown M, Louthrenoo W, Vazquez-Mellado J, Eliseev M, McCarthy G, Stamp LK, Perez-Ruiz F, Sivera F, Ea HK, Gerritsen M, Scire C, Cavagna L, Lin C, Chou YY, Tausche AK, da Rocha Castelar-Pinheiro G, Janssen M, Chen JH, Slot O, Cimmino M, Uhlig T, Jansen TL
Ann Rheum Dis 2016 Jan;75(1):178-82. Epub 2014 Oct 28 doi: 10.1136/annrheumdis-2014-206364. [Epub ahead of print] PMID: 25351521
Terslev L, Gutierrez M, Christensen R, Balint PV, Bruyn GA, Delle Sedie A, Filippucci E, Garrido J, Hammer HB, Iagnocco A, Kane D, Kaeley GS, Keen H, Mandl P, Naredo E, Pineda C, Schicke B, Thiele R, D'Agostino MA, Schmidt WA; OMERACT US Gout Task Force
J Rheumatol 2015 Nov;42(11):2149-54. Epub 2015 Oct 15 doi: 10.3899/jrheum.150366. [Epub ahead of print] PMID: 26472419
Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M
Rheumatology (Oxford) 2015 Dec;54(12):2145-50. Epub 2015 Jul 12 doi: 10.1093/rheumatology/kev246. [Epub ahead of print] PMID: 26170376

Recent systematic reviews

Phipps-Green AJ, Merriman ME, Topless R, Altaf S, Montgomery GW, Franklin C, Jones GT, van Rij AM, White D, Stamp LK, Dalbeth N, Merriman TR
Ann Rheum Dis 2016 Jan;75(1):124-30. Epub 2014 Sep 3 doi: 10.1136/annrheumdis-2014-205877. [Epub ahead of print] PMID: 25187157
Neogi T, Jansen TL, Dalbeth N, Fransen J, Schumacher HR, Berendsen D, Brown M, Choi H, Edwards NL, Janssens HJ, Lioté F, Naden RP, Nuki G, Ogdie A, Perez-Ruiz F, Saag K, Singh JA, Sundy JS, Tausche AK, Vaquez-Mellado J, Yarows SA, Taylor WJ
Ann Rheum Dis 2015 Oct;74(10):1789-98. doi: 10.1136/annrheumdis-2015-208237. PMID: 26359487Free PMC Article
Ungprasert P, Srivali N, Thongprayoon C
Parkinsonism Relat Disord 2015 Oct;21(10):1238-42. Epub 2015 Aug 28 doi: 10.1016/j.parkreldis.2015.08.030. [Epub ahead of print] PMID: 26330027
Rai SK, Burns LC, De Vera MA, Haji A, Giustini D, Choi HK
Semin Arthritis Rheum 2015 Aug;45(1):75-80. Epub 2015 Feb 19 doi: 10.1016/j.semarthrit.2015.02.004. [Epub ahead of print] PMID: 25912932
Ogdie A, Taylor WJ, Weatherall M, Fransen J, Jansen TL, Neogi T, Schumacher HR, Dalbeth N
Ann Rheum Dis 2015 Oct;74(10):1868-74. Epub 2014 Jun 10 doi: 10.1136/annrheumdis-2014-205431. [Epub ahead of print] PMID: 24915980Free PMC Article

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