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Glucose

MedGen UID:
42238
Concept ID:
C0017725
Pharmacologic Substance
Synonyms: D Glucose; D-Glucose; Dextrose
SNOMED CT: Glucose (67079006); Glucose product (111138002); Glucose preparation (111138002); D-glucose (67079006); Dextrose (67079006); Glucose (111138002); Dextrose preparation (111138002); Dextrose product (111138002)
 

Definition

A hexose with an aldehyde group; in which each of the 5 remaining carbons other than the aldehyde group has one hydroxyl group in the R,S,R, and R configuration counting from the first hydroxyl containing carbon next to the aldehyde in the straight chain (Fisher) projection; otherwise all carbons have exclusively hydrogens. Occurs mostly as pyran (6-membered oxygen containing ring or oxane) and rarely as furan (5-membered oxygen containing ring) or straight chain. When glucose forms a ring an additional ""anomeric"" asymmetric carbon is created which is denoted as ""alpha"" or ""beta"". For isomers see http://en.wikipedia.org/wiki/Glucose. [from NCI]

Recent clinical studies

Etiology

Palmer CS, Anzinger JJ, Zhou J, Gouillou M, Landay A, Jaworowski A, McCune JM, Crowe SM
J Immunol 2014 Dec 1;193(11):5595-603. Epub 2014 Nov 3 doi: 10.4049/jimmunol.1303092. [Epub ahead of print] PMID: 25367121
González F, Sia CL, Shepard MK, Rote NS, Minium J
J Clin Endocrinol Metab 2014 Nov;99(11):E2244-51. Epub 2014 Jul 31 doi: 10.1210/jc.2014-2046. [Epub ahead of print] PMID: 25078146Free PMC Article
Garrido P, Salehzadeh F, Duque-Guimaraes DE, Al-Khalili L
Metabolism 2014 Sep;63(9):1178-87. Epub 2014 Jun 13 doi: 10.1016/j.metabol.2014.06.003. [Epub ahead of print] PMID: 25034385
Feng F, Chen L, Lian C, Xia H, Zhou Y, Yao Q, Chen K
J Proteomics 2014 Aug 28;108:124-32. Epub 2014 May 27 doi: 10.1016/j.jprot.2014.05.015. [Epub ahead of print] PMID: 24878427
Haugen G, Bollerslev J, Henriksen T
Acta Obstet Gynecol Scand 2014 Aug;93(8):778-85. Epub 2014 Jun 4 doi: 10.1111/aogs.12419. [Epub ahead of print] PMID: 24806823

Diagnosis

Omar M, Ettinger M, Reichling M, Petri M, Lichtinghagen R, Guenther D, Suero EM, Jagodzinski M, Krettek C
J Bone Joint Surg Am 2014 Dec 17;96(24):2032-7. doi: 10.2106/JBJS.N.00173. PMID: 25520336
Karim S, Liaskou E, Fear J, Garg A, Reynolds G, Claridge L, Adams DH, Newsome PN, Lalor PF
Am J Physiol Gastrointest Liver Physiol 2014 Dec 15;307(12):G1180-90. Epub 2014 Oct 23 doi: 10.1152/ajpgi.00377.2013. [Epub ahead of print] PMID: 25342050Free PMC Article
Guan X
Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R585-96. Epub 2014 Jul 2 doi: 10.1152/ajpregu.00096.2014. [Epub ahead of print] PMID: 24990862Free PMC Article
Zhong S, Jang CH
Biosens Bioelectron 2014 Sep 15;59:293-9. Epub 2014 Apr 8 doi: 10.1016/j.bios.2014.03.070. [Epub ahead of print] PMID: 24747204
del Barrio M, de Marcos S, Cebolla V, Heiland J, Wilhelm S, Hirsch T, Galbán J
Biosens Bioelectron 2014 Sep 15;59:14-20. Epub 2014 Mar 18 doi: 10.1016/j.bios.2014.02.076. [Epub ahead of print] PMID: 24686223

Therapy

Palmer CS, Anzinger JJ, Zhou J, Gouillou M, Landay A, Jaworowski A, McCune JM, Crowe SM
J Immunol 2014 Dec 1;193(11):5595-603. Epub 2014 Nov 3 doi: 10.4049/jimmunol.1303092. [Epub ahead of print] PMID: 25367121
Zhang D, Li J, Wang F, Hu J, Wang S, Sun Y
Cancer Lett 2014 Dec 28;355(2):176-83. Epub 2014 Sep 10 doi: 10.1016/j.canlet.2014.09.003. [Epub ahead of print] PMID: 25218591
Stein P, Berg JK, Morrow L, Polidori D, Artis E, Rusch S, Vaccaro N, Devineni D
Metabolism 2014 Oct;63(10):1296-303. Epub 2014 Jul 9 doi: 10.1016/j.metabol.2014.07.003. [Epub ahead of print] PMID: 25110280
Mandal SM, Mahata D, Migliolo L, Parekh A, Addy PS, Mandal M, Basak A
J Biol Chem 2014 Sep 12;289(37):25468-73. Epub 2014 Jul 22 doi: 10.1074/jbc.C114.571778. [Epub ahead of print] PMID: 25053418Free PMC Article
Xu H, Bègue L, Sauve L, Bushman BJ
Appetite 2014 Oct;81:8-11. Epub 2014 May 29 doi: 10.1016/j.appet.2014.05.023. [Epub ahead of print] PMID: 24882450

Prognosis

Omar M, Ettinger M, Reichling M, Petri M, Lichtinghagen R, Guenther D, Suero EM, Jagodzinski M, Krettek C
J Bone Joint Surg Am 2014 Dec 17;96(24):2032-7. doi: 10.2106/JBJS.N.00173. PMID: 25520336
Kuriyama C, Xu JZ, Lee SP, Qi J, Kimata H, Kakimoto T, Nakayama K, Watanabe Y, Taniuchi N, Hikida K, Matsushita Y, Arakawa K, Saito A, Ueta K, Shiotani M
J Pharmacol Exp Ther 2014 Nov;351(2):423-31. Epub 2014 Sep 12 doi: 10.1124/jpet.114.217992. [Epub ahead of print] PMID: 25216746
Dirinck EL, Dirtu AC, Govindan M, Covaci A, Van Gaal LF, Jorens PG
Diabetes Care 2014 Jul;37(7):1951-8. doi: 10.2337/dc13-2329. PMID: 24963112
Thorsen K, Drengstig T, Ruoff P
Am J Physiol Cell Physiol 2014 Aug 15;307(4):C320-37. Epub 2014 Jun 4 doi: 10.1152/ajpcell.00068.2013. [Epub ahead of print] PMID: 24898586Free PMC Article
Thomaseth K, Brehm A, Pavan A, Pacini G, Roden M
Am J Physiol Regul Integr Comp Physiol 2014 Aug 1;307(3):R321-31. Epub 2014 May 21 doi: 10.1152/ajpregu.00314.2013. [Epub ahead of print] PMID: 24848363

Clinical prediction guides

Omar M, Ettinger M, Reichling M, Petri M, Lichtinghagen R, Guenther D, Suero EM, Jagodzinski M, Krettek C
J Bone Joint Surg Am 2014 Dec 17;96(24):2032-7. doi: 10.2106/JBJS.N.00173. PMID: 25520336
Stein P, Berg JK, Morrow L, Polidori D, Artis E, Rusch S, Vaccaro N, Devineni D
Metabolism 2014 Oct;63(10):1296-303. Epub 2014 Jul 9 doi: 10.1016/j.metabol.2014.07.003. [Epub ahead of print] PMID: 25110280
Sun Y, Zhang Y, Cheng B, Dong Y, Pan C, Li T, Xie Z
Anesth Analg 2014 Dec;119(6):1373-80. doi: 10.1213/ANE.0000000000000383. PMID: 25068691
Mandal SM, Mahata D, Migliolo L, Parekh A, Addy PS, Mandal M, Basak A
J Biol Chem 2014 Sep 12;289(37):25468-73. Epub 2014 Jul 22 doi: 10.1074/jbc.C114.571778. [Epub ahead of print] PMID: 25053418Free PMC Article
Zhong S, Jang CH
Biosens Bioelectron 2014 Sep 15;59:293-9. Epub 2014 Apr 8 doi: 10.1016/j.bios.2014.03.070. [Epub ahead of print] PMID: 24747204

Recent systematic reviews

Feng F, Chen L, Lian C, Xia H, Zhou Y, Yao Q, Chen K
J Proteomics 2014 Aug 28;108:124-32. Epub 2014 May 27 doi: 10.1016/j.jprot.2014.05.015. [Epub ahead of print] PMID: 24878427
Lisonkova S, Sabr Y, Joseph KS
J Obstet Gynaecol Can 2014 Feb;36(2):116-22. PMID: 24518909
Sievenpiper JL, de Souza RJ, Cozma AI, Chiavaroli L, Ha V, Mirrahimi A
Curr Opin Lipidol 2014 Feb;25(1):8-19. doi: 10.1097/MOL.0000000000000042. PMID: 24370846
Oosterveer MH, Schoonjans K
Cell Mol Life Sci 2014 Apr;71(8):1453-67. Epub 2013 Nov 7 doi: 10.1007/s00018-013-1505-z. [Epub ahead of print] PMID: 24196749
Chen W, Li F, He C, Zhu Y, Tan W
Ir J Med Sci 2014 Jun;183(2):283-91. Epub 2013 Aug 30 doi: 10.1007/s11845-013-1007-x. [Epub ahead of print] PMID: 23990176

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