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Body mass index(BMI)

MedGen UID:
449535
Concept ID:
C2240399
Finding
Synonyms: BMI
 
Cytogenetic location: 7q32.3
OMIM: 606641

Definition

Body mass index (BMI), which reflects the amount of fat, lean mass, and body build, is a heterogeneous trait influenced by both genetic and environmental factors. Several studies have estimated the heritability of body mass index to be 40 to 55% (Bouchard et al., 1998; Rice et al., 1999). [from OMIM]

Recent clinical studies

Etiology

Cohen WR, Hayes-Gill B
Acta Obstet Gynecol Scand 2014 Jun;93(6):590-5. Epub 2014 Apr 30 doi: 10.1111/aogs.12387. [Epub ahead of print] PMID: 24684703
Chen Y, Copeland WK, Vedanthan R, Grant E, Lee JE, Gu D, Gupta PC, Ramadas K, Inoue M, Tsugane S, Tamakoshi A, Gao YT, Yuan JM, Shu XO, Ozasa K, Tsuji I, Kakizaki M, Tanaka H, Nishino Y, Chen CJ, Wang R, Yoo KY, Ahn YO, Ahsan H, Pan WH, Chen CS, Pednekar MS, Sauvaget C, Sasazuki S, Yang G, Koh WP, Xiang YB, Ohishi W, Watanabe T, Sugawara Y, Matsuo K, You SL, Park SK, Kim DH, Parvez F, Chuang SY, Ge W, Rolland B, McLerran D, Sinha R, Thornquist M, Kang D, Feng Z, Boffetta P, Zheng W, He J, Potter JD
BMJ 2013 Oct 1;347:f5446. PMID: 24473060Free PMC Article
Pickkers P, de Keizer N, Dusseljee J, Weerheijm D, van der Hoeven JG, Peek N
Crit Care Med 2013 Aug;41(8):1878-83. doi: 10.1097/CCM.0b013e31828a2aa1. PMID: 23685638
Masuda H, Kagawa M, Kawakami S, Numao N, Matsuoka Y, Yokoyama M, Yamamoto S, Yonese J, Fukui I, Kihara K
Int J Urol 2013 Jul;20(7):701-7. Epub 2012 Nov 27 doi: 10.1111/iju.12023. [Epub ahead of print] PMID: 23186107
Keeling WB, Kilgo PD, Puskas JD, Halkos ME, Lattouf OM, Guyton RA, Thourani VH
J Thorac Cardiovasc Surg 2013 Dec;146(6):1442-8. Epub 2012 Oct 16 doi: 10.1016/j.jtcvs.2012.09.035. [Epub ahead of print] PMID: 23084105

Diagnosis

Cohen WR, Hayes-Gill B
Acta Obstet Gynecol Scand 2014 Jun;93(6):590-5. Epub 2014 Apr 30 doi: 10.1111/aogs.12387. [Epub ahead of print] PMID: 24684703
Farrell SW, Finley CE, Radford NB, Haskell WL
Circ Heart Fail 2013 Sep 1;6(5):898-905. Epub 2013 Jul 19 doi: 10.1161/CIRCHEARTFAILURE.112.000088. [Epub ahead of print] PMID: 23873472
Moura Neto A, Parisi MC, Tambascia MA, Alegre SM, Pavin EJ, Zantut-Wittmann DE
Endocr J 2013;60(7):877-84. Epub 2013 Apr 5 [Epub ahead of print] PMID: 23558976
Cheng Y, Wang N, Wang K, Wang J, Tan B, Jia Y, Dou Y, Yu J
Jpn J Clin Oncol 2013 Feb;43(2):146-53. Epub 2012 Dec 21 doi: 10.1093/jjco/hys212. [Epub ahead of print] PMID: 23264675
Keeling WB, Kilgo PD, Puskas JD, Halkos ME, Lattouf OM, Guyton RA, Thourani VH
J Thorac Cardiovasc Surg 2013 Dec;146(6):1442-8. Epub 2012 Oct 16 doi: 10.1016/j.jtcvs.2012.09.035. [Epub ahead of print] PMID: 23084105

Therapy

Cohen WR, Hayes-Gill B
Acta Obstet Gynecol Scand 2014 Jun;93(6):590-5. Epub 2014 Apr 30 doi: 10.1111/aogs.12387. [Epub ahead of print] PMID: 24684703
de Groot S, Post MW, Hoekstra T, Valent LJ, Faber WX, van der Woude LH
Arch Phys Med Rehabil 2014 Jun;95(6):1083-92. Epub 2014 Feb 14 doi: 10.1016/j.apmr.2014.01.024. [Epub ahead of print] PMID: 24534297
Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm EB, Danaei G
Lancet 2014 Mar 15;383(9921):970-83. Epub 2013 Nov 22 doi: 10.1016/S0140-6736(13)61836-X. [Epub ahead of print] PMID: 24269108Free PMC Article
Keeling WB, Kilgo PD, Puskas JD, Halkos ME, Lattouf OM, Guyton RA, Thourani VH
J Thorac Cardiovasc Surg 2013 Dec;146(6):1442-8. Epub 2012 Oct 16 doi: 10.1016/j.jtcvs.2012.09.035. [Epub ahead of print] PMID: 23084105
Stan MN, Ammash NM, Warnes CA, Brennan MD, Thapa P, Nannenga MR, Bahn RS
Int J Cardiol 2013 Aug 10;167(3):821-6. Epub 2012 Mar 2 doi: 10.1016/j.ijcard.2012.02.015. [Epub ahead of print] PMID: 22386642

Prognosis

Cohen WR, Hayes-Gill B
Acta Obstet Gynecol Scand 2014 Jun;93(6):590-5. Epub 2014 Apr 30 doi: 10.1111/aogs.12387. [Epub ahead of print] PMID: 24684703
Farrell SW, Finley CE, Radford NB, Haskell WL
Circ Heart Fail 2013 Sep 1;6(5):898-905. Epub 2013 Jul 19 doi: 10.1161/CIRCHEARTFAILURE.112.000088. [Epub ahead of print] PMID: 23873472
Pickkers P, de Keizer N, Dusseljee J, Weerheijm D, van der Hoeven JG, Peek N
Crit Care Med 2013 Aug;41(8):1878-83. doi: 10.1097/CCM.0b013e31828a2aa1. PMID: 23685638
Keeling WB, Kilgo PD, Puskas JD, Halkos ME, Lattouf OM, Guyton RA, Thourani VH
J Thorac Cardiovasc Surg 2013 Dec;146(6):1442-8. Epub 2012 Oct 16 doi: 10.1016/j.jtcvs.2012.09.035. [Epub ahead of print] PMID: 23084105
Wang C, Liu Y, Yang Q, Dai X, Wu S, Wang W, Ji X, Li L, Fang X
Int J Stroke 2013 Jun;8(4):245-50. Epub 2012 Oct 8 doi: 10.1111/j.1747-4949.2012.00830.x. [Epub ahead of print] PMID: 23039874

Clinical prediction guides

Cohen WR, Hayes-Gill B
Acta Obstet Gynecol Scand 2014 Jun;93(6):590-5. Epub 2014 Apr 30 doi: 10.1111/aogs.12387. [Epub ahead of print] PMID: 24684703
Chen Y, Copeland WK, Vedanthan R, Grant E, Lee JE, Gu D, Gupta PC, Ramadas K, Inoue M, Tsugane S, Tamakoshi A, Gao YT, Yuan JM, Shu XO, Ozasa K, Tsuji I, Kakizaki M, Tanaka H, Nishino Y, Chen CJ, Wang R, Yoo KY, Ahn YO, Ahsan H, Pan WH, Chen CS, Pednekar MS, Sauvaget C, Sasazuki S, Yang G, Koh WP, Xiang YB, Ohishi W, Watanabe T, Sugawara Y, Matsuo K, You SL, Park SK, Kim DH, Parvez F, Chuang SY, Ge W, Rolland B, McLerran D, Sinha R, Thornquist M, Kang D, Feng Z, Boffetta P, Zheng W, He J, Potter JD
BMJ 2013 Oct 1;347:f5446. PMID: 24473060Free PMC Article
Pickkers P, de Keizer N, Dusseljee J, Weerheijm D, van der Hoeven JG, Peek N
Crit Care Med 2013 Aug;41(8):1878-83. doi: 10.1097/CCM.0b013e31828a2aa1. PMID: 23685638
Masuda H, Kagawa M, Kawakami S, Numao N, Matsuoka Y, Yokoyama M, Yamamoto S, Yonese J, Fukui I, Kihara K
Int J Urol 2013 Jul;20(7):701-7. Epub 2012 Nov 27 doi: 10.1111/iju.12023. [Epub ahead of print] PMID: 23186107
Keeling WB, Kilgo PD, Puskas JD, Halkos ME, Lattouf OM, Guyton RA, Thourani VH
J Thorac Cardiovasc Surg 2013 Dec;146(6):1442-8. Epub 2012 Oct 16 doi: 10.1016/j.jtcvs.2012.09.035. [Epub ahead of print] PMID: 23084105

Recent systematic reviews

Munsell MF, Sprague BL, Berry DA, Chisholm G, Trentham-Dietz A
Epidemiol Rev 2014;36(1):114-36. doi: 10.1093/epirev/mxt010. PMID: 24375928Free PMC Article
Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm EB, Danaei G
Lancet 2014 Mar 15;383(9921):970-83. Epub 2013 Nov 22 doi: 10.1016/S0140-6736(13)61836-X. [Epub ahead of print] PMID: 24269108Free PMC Article
Chen Y, Copeland WK, Vedanthan R, Grant E, Lee JE, Gu D, Gupta PC, Ramadas K, Inoue M, Tsugane S, Tamakoshi A, Gao YT, Yuan JM, Shu XO, Ozasa K, Tsuji I, Kakizaki M, Tanaka H, Nishino Y, Chen CJ, Wang R, Yoo KY, Ahn YO, Ahsan H, Pan WH, Chen CS, Pednekar MS, Sauvaget C, Sasazuki S, Yang G, Koh WP, Xiang YB, Ohishi W, Watanabe T, Sugawara Y, Matsuo K, You SL, Park SK, Kim DH, Parvez F, Chuang SY, Ge W, Rolland B, McLerran D, Sinha R, Thornquist M, Kang D, Feng Z, Boffetta P, Zheng W, He J, Potter JD
BMJ 2013 Oct 1;347:f5446. PMID: 24473060Free PMC Article
Min J, Chiu DT, Wang Y
Obes Rev 2013 Nov;14(11):871-82. Epub 2013 Aug 27 doi: 10.1111/obr.12065. [Epub ahead of print] PMID: 23980914
Hooley M, Skouteris H, Boganin C, Satur J, Kilpatrick N
Syst Rev 2012 Nov 21;1:57. doi: 10.1186/2046-4053-1-57. [Epub ahead of print] PMID: 23171603Free PMC Article

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