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Substance abuse

MedGen UID:
152849
•Concept ID:
C0740858
•
Mental or Behavioral Dysfunction
Synonyms: Abuse, Substance; Substance Abuse; Substance Abuses
SNOMED CT: Substance abuse (66214007); Harmful substance use (66214007)
 
Monarch Initiative: MONDO:0002491

Definition

Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance abuse

Professional guidelines

PubMed

Borderline Personality Disorder: Clinical Guidelines for Treatment.
Stone MH
Psychodyn Psychiatry 2022 Spring;50(1):45-63. doi: 10.1521/pdps.2022.50.1.45. PMID: 35235397
Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017.
Hiemke C, Bergemann N, Clement HW, Conca A, Deckert J, Domschke K, Eckermann G, Egberts K, Gerlach M, Greiner C, Gründer G, Haen E, Havemann-Reinecke U, Hefner G, Helmer R, Janssen G, Jaquenoud E, Laux G, Messer T, Mössner R, Müller MJ, Paulzen M, Pfuhlmann B, Riederer P, Saria A, Schoppek B, Schoretsanitis G, Schwarz M, Gracia MS, Stegmann B, Steimer W, Stingl JC, Uhr M, Ulrich S, Unterecker S, Waschgler R, Zernig G, Zurek G, Baumann P
Pharmacopsychiatry 2018 Jan;51(1-02):9-62. Epub 2017 Sep 14 doi: 10.1055/s-0043-116492. PMID: 28910830
Nonpharmacologic Management of Chronic Insomnia.
Maness DL, Khan M
Am Fam Physician 2015 Dec 15;92(12):1058-64. PMID: 26760592

Curated

UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

Recent clinical studies

Etiology

Adolescent Substance Abuse.
Garofoli M
Prim Care 2020 Jun;47(2):383-394. Epub 2020 Feb 21 doi: 10.1016/j.pop.2020.02.013. PMID: 32423721
Employment services and substance abuse treatment.
Sherba RT, Coxe KA, Gersper BE, Linley JV
J Subst Abuse Treat 2018 Apr;87:70-78. Epub 2018 Feb 8 doi: 10.1016/j.jsat.2018.01.015. PMID: 29471929
Substance Abuse Prevention, Assessment, and Treatment for Lesbian, Gay, Bisexual, and Transgender Youth.
Aromin RA Jr
Pediatr Clin North Am 2016 Dec;63(6):1057-1077. Epub 2016 Oct 12 doi: 10.1016/j.pcl.2016.07.007. PMID: 27865333
Substance Use and Substance Abuse--What's in a Name?
Savage CL
J Addict Nurs 2016 Jan-Mar;27(1):47-50. doi: 10.1097/JAN.0000000000000111. PMID: 26950842
Alcohol and other substance abuse and impairment among physicians in residency training.
Aach RD, Girard DE, Humphrey H, McCue JD, Reuben DB, Smith JW, Wallenstein L, Ginsburg J
Ann Intern Med 1992 Feb 1;116(3):245-54. doi: 10.7326/0003-4819-116-3-245. PMID: 1728207

Diagnosis

Community-acquired skin and soft-tissue infections in people who inject drugs.
Allaw F, Zakhour J, Kanj SS
Curr Opin Infect Dis 2023 Apr 1;36(2):67-73. Epub 2023 Jan 25 doi: 10.1097/QCO.0000000000000902. PMID: 36718912
Application of Metabonomics in Substance Abuse Toxicology Research.
Yan XY, Xiang P, Yu ZG, Yan H
Fa Yi Xue Za Zhi 2022 Jun 25;38(3):400-407. doi: 10.12116/j.issn.1004-5619.2019.391203. PMID: 36221836
Adolescent Substance Abuse.
Garofoli M
Prim Care 2020 Jun;47(2):383-394. Epub 2020 Feb 21 doi: 10.1016/j.pop.2020.02.013. PMID: 32423721
Developing a plan of care using the Roper, Logan and Tierney model.
Mooney M, O'Brien F
Br J Nurs 2006 Sep 14-27;15(16):887-92. doi: 10.12968/bjon.2006.15.16.21854. PMID: 17108861
Substance abuse and criminality.
Sinha R, Easton C
J Am Acad Psychiatry Law 1999;27(4):513-26. PMID: 10638781

Therapy

Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.
Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Lithium treatment of Bipolar disorder in adults: A systematic review of randomized trials and meta-analyses.
Fountoulakis KN, Tohen M, Zarate CA Jr
Eur Neuropsychopharmacol 2022 Jan;54:100-115. doi: 10.1016/j.euroneuro.2021.10.003. PMID: 34980362Free PMC Article
The Role of New Technologies to Prevent Suicide in Adolescence: A Systematic Review of the Literature.
Forte A, Sarli G, Polidori L, Lester D, Pompili M
Medicina (Kaunas) 2021 Jan 26;57(2) doi: 10.3390/medicina57020109. PMID: 33530342Free PMC Article
Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.
Crippa JA, Guimarães FS, Campos AC, Zuardi AW
Front Immunol 2018;9:2009. Epub 2018 Sep 21 doi: 10.3389/fimmu.2018.02009. PMID: 30298064Free PMC Article
Prevention, early intervention, harm reduction, and treatment of substance use in young people.
Stockings E, Hall WD, Lynskey M, Morley KI, Reavley N, Strang J, Patton G, Degenhardt L
Lancet Psychiatry 2016 Mar;3(3):280-96. Epub 2016 Feb 18 doi: 10.1016/S2215-0366(16)00002-X. PMID: 26905481

Prognosis

A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders.
Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ, Mortensen PB, Eaton WW
JAMA Psychiatry 2014 May;71(5):573-81. doi: 10.1001/jamapsychiatry.2014.16. PMID: 24806211
Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis.
Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA
BMJ 2011 Feb 22;342:d671. doi: 10.1136/bmj.d671. PMID: 21343207Free PMC Article
Not mission impossible.
Parsons J
Aust Fam Physician 2009 Mar;38(3):85. PMID: 19283243
Impaired healthcare professional.
Baldisseri MR
Crit Care Med 2007 Feb;35(2 Suppl):S106-16. doi: 10.1097/01.CCM.0000252918.87746.96. PMID: 17242598
Aboriginal health.
MacMillan HL, MacMillan AB, Offord DR, Dingle JL
CMAJ 1996 Dec 1;155(11):1569-78. PMID: 8956834Free PMC Article

Clinical prediction guides

Algorithms to Identify Nonmedical Opioid Use.
Brondeel KC, Malone KT, Ditmars FR, Vories BA, Ahmadzadeh S, Tirumala S, Fox CJ, Shekoohi S, Cornett EM, Kaye AD
Curr Pain Headache Rep 2023 May;27(5):81-88. Epub 2023 Apr 6 doi: 10.1007/s11916-023-01104-7. PMID: 37022564
Co-occurring mental and substance abuse disorders: a review on the potential predictors and clinical outcomes.
Najt P, Fusar-Poli P, Brambilla P
Psychiatry Res 2011 Apr 30;186(2-3):159-64. Epub 2010 Aug 21 doi: 10.1016/j.psychres.2010.07.042. PMID: 20728943
Urine drug screening: practical guide for clinicians.
Moeller KE, Lee KC, Kissack JC
Mayo Clin Proc 2008 Jan;83(1):66-76. doi: 10.4065/83.1.66. PMID: 18174009
Screening for serious mental illness in the general population.
Kessler RC, Barker PR, Colpe LJ, Epstein JF, Gfroerer JC, Hiripi E, Howes MJ, Normand SL, Manderscheid RW, Walters EE, Zaslavsky AM
Arch Gen Psychiatry 2003 Feb;60(2):184-9. doi: 10.1001/archpsyc.60.2.184. PMID: 12578436
The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test.
Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA
Arch Intern Med 1998 Sep 14;158(16):1789-95. doi: 10.1001/archinte.158.16.1789. PMID: 9738608

Recent systematic reviews

Supervised Injection Facilities as Harm Reduction: A Systematic Review.
Levengood TW, Yoon GH, Davoust MJ, Ogden SN, Marshall BDL, Cahill SR, Bazzi AR
Am J Prev Med 2021 Nov;61(5):738-749. Epub 2021 Jul 1 doi: 10.1016/j.amepre.2021.04.017. PMID: 34218964Free PMC Article
The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis.
Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM
J Hepatol 2020 Sep;73(3):523-532. Epub 2020 Apr 23 doi: 10.1016/j.jhep.2020.04.008. PMID: 32335166Free PMC Article
Motivational interviewing for substance abuse.
Smedslund G, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K
Cochrane Database Syst Rev 2011 May 11;2011(5):CD008063. doi: 10.1002/14651858.CD008063.pub2. PMID: 21563163Free PMC Article
Schizophrenia and violence: systematic review and meta-analysis.
Fazel S, Gulati G, Linsell L, Geddes JR, Grann M
PLoS Med 2009 Aug;6(8):e1000120. Epub 2009 Aug 11 doi: 10.1371/journal.pmed.1000120. PMID: 19668362Free PMC Article
Research on religion, spirituality, and mental health: a review.
Koenig HG
Can J Psychiatry 2009 May;54(5):283-91. doi: 10.1177/070674370905400502. PMID: 19497160

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Practice guidelines

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    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
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    • PMC Articles
      Related information in PubMed Central Links
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