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Polyradiculoneuropathy, Chronic Inflammatory Demyelinating(CIDP)

MedGen UID:
98292
Concept ID:
C0393819
Disease or Syndrome
Synonyms: Chronic Inflammatory Demyelinating Polyradiculoneuropathy; Chronic Inflammatory Polyradiculoneuropathies; Chronic Inflammatory Polyradiculoneuropathy; Chronic Inflammatory Polyradiculopathies; Chronic Inflammatory Polyradiculopathy; CIDP; Inflammatory Polyradiculopathies, Chronic; Inflammatory Polyradiculopathy, Chronic; Polyneuropathy, Inflammatory Demyelinating, Chronic; Polyradiculoneuropathies, Chronic Inflammatory; Polyradiculoneuropathy, Chronic Inflammatory; Polyradiculopathies, Chronic Inflammatory; Polyradiculopathy, Chronic Inflammatory
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: CIDP - Chronic inflammatory demyelinating polyradiculoneuropathy (128209004); CIDP (128209004); Chronic inflammatory demyelinating polyradiculoneuropathy (128209004); Chronic inflammatory demyelinating polyneuropathy (444728005); CIDP (Chronic inflammatory demyelinating polyneuropathy) (444728005)
 
OMIM®: 139393
Orphanet: ORPHA2932

Definition

An immunologic inflammatory disorder characterized by loss of myelin in the peripheral nerves. Patients present with progressive weakness and loss of sensory function in the legs and arms. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolyradiculoneuropathy, Chronic Inflammatory Demyelinating
Follow this link to review classifications for Polyradiculoneuropathy, Chronic Inflammatory Demyelinating in Orphanet.

Recent clinical studies

Etiology

Devaux JJ, Miura Y, Fukami Y, Inoue T, Manso C, Belghazi M, Sekiguchi K, Kokubun N, Ichikawa H, Wong AH, Yuki N
Neurology 2016 Mar 1;86(9):800-7. Epub 2016 Feb 3 doi: 10.1212/WNL.0000000000002418. [Epub ahead of print] PMID: 26843559Free PMC Article
Allen JA, Lewis RA
Neurology 2015 Aug 11;85(6):498-504. Epub 2015 Jul 15 doi: 10.1212/WNL.0000000000001833. [Epub ahead of print] PMID: 26180143
Dyck PJ, Taylor BV, Davies JL, Mauermann ML, Litchy WJ, Klein CJ, Dyck PJ
Muscle Nerve 2015 Oct;52(4):488-97. Epub 2015 Aug 13 doi: 10.1002/mus.24707. [Epub ahead of print] PMID: 25976871Free PMC Article
Cabasson S, Tardieu M, Meunier A, Rouanet-Larriviere MF, Boulay C, Pedespan JM
Brain Dev 2015 Nov;37(10):943-51. Epub 2015 Apr 25 doi: 10.1016/j.braindev.2015.04.001. [Epub ahead of print] PMID: 25921353
Miura Y, Devaux JJ, Fukami Y, Manso C, Belghazi M, Wong AH, Yuki N; CNTN1-CIDP Study Group
Brain 2015 Jun;138(Pt 6):1484-91. Epub 2015 Mar 25 doi: 10.1093/brain/awv054. [Epub ahead of print] PMID: 25808373Free PMC Article

Diagnosis

Devaux JJ, Miura Y, Fukami Y, Inoue T, Manso C, Belghazi M, Sekiguchi K, Kokubun N, Ichikawa H, Wong AH, Yuki N
Neurology 2016 Mar 1;86(9):800-7. Epub 2016 Feb 3 doi: 10.1212/WNL.0000000000002418. [Epub ahead of print] PMID: 26843559Free PMC Article
Shah A, Rison RA, Beydoun SR
J Clin Neuromuscul Dis 2015 Dec;17(2):78-83. doi: 10.1097/CND.0000000000000094. PMID: 26583495
Allen JA, Lewis RA
Neurology 2015 Aug 11;85(6):498-504. Epub 2015 Jul 15 doi: 10.1212/WNL.0000000000001833. [Epub ahead of print] PMID: 26180143
Cabasson S, Tardieu M, Meunier A, Rouanet-Larriviere MF, Boulay C, Pedespan JM
Brain Dev 2015 Nov;37(10):943-51. Epub 2015 Apr 25 doi: 10.1016/j.braindev.2015.04.001. [Epub ahead of print] PMID: 25921353
Névoret ML, Vinik AI
J Diabetes Complications 2015 Mar;29(2):313-7. Epub 2014 Nov 6 doi: 10.1016/j.jdiacomp.2014.10.012. [Epub ahead of print] PMID: 25466645

Therapy

Wong AH, Fukami Y, Sudo M, Kokubun N, Hamada S, Yuki N
J Neurol Neurosurg Psychiatry 2016 Mar;87(3):275-9. Epub 2015 Mar 26 doi: 10.1136/jnnp-2014-309964. [Epub ahead of print] PMID: 25814494
Allen JA, Lewis RA
Neurology 2015 Aug 11;85(6):498-504. Epub 2015 Jul 15 doi: 10.1212/WNL.0000000000001833. [Epub ahead of print] PMID: 26180143
Klehmet J, Staudt M, Ulm L, Unterwalder N, Meisel A, Meisel C
J Neuroimmunol 2015 Jun 15;283:17-22. Epub 2015 Apr 7 doi: 10.1016/j.jneuroim.2015.03.023. [Epub ahead of print] PMID: 26004151
Cabasson S, Tardieu M, Meunier A, Rouanet-Larriviere MF, Boulay C, Pedespan JM
Brain Dev 2015 Nov;37(10):943-51. Epub 2015 Apr 25 doi: 10.1016/j.braindev.2015.04.001. [Epub ahead of print] PMID: 25921353
Miura Y, Devaux JJ, Fukami Y, Manso C, Belghazi M, Wong AH, Yuki N; CNTN1-CIDP Study Group
Brain 2015 Jun;138(Pt 6):1484-91. Epub 2015 Mar 25 doi: 10.1093/brain/awv054. [Epub ahead of print] PMID: 25808373Free PMC Article

Prognosis

Devaux JJ, Miura Y, Fukami Y, Inoue T, Manso C, Belghazi M, Sekiguchi K, Kokubun N, Ichikawa H, Wong AH, Yuki N
Neurology 2016 Mar 1;86(9):800-7. Epub 2016 Feb 3 doi: 10.1212/WNL.0000000000002418. [Epub ahead of print] PMID: 26843559Free PMC Article
Blum S, Csurhes P, McCombe P
J Neuroimmunol 2015 Aug 15;285:53-6. Epub 2015 May 20 doi: 10.1016/j.jneuroim.2015.05.017. [Epub ahead of print] PMID: 26198918
Vallat JM, Mathis S, Ghorab K, Milor MA, Richard L, Magy L
Eur Neurol 2015;73(5-6):294-302. Epub 2015 Apr 29 doi: 10.1159/000381767. [Epub ahead of print] PMID: 25925430
Svahn J, Antoine JC, Camdessanché JP
Rev Neurol (Paris) 2014 Dec;170(12):808-17. Epub 2014 Nov 6 doi: 10.1016/j.neurol.2014.10.009. [Epub ahead of print] PMID: 25459126
Eldar AH, Chapman J
Autoimmun Rev 2014 Apr-May;13(4-5):525-30. Epub 2014 Jan 13 doi: 10.1016/j.autrev.2014.01.033. [Epub ahead of print] PMID: 24434363

Clinical prediction guides

Klehmet J, Staudt M, Ulm L, Unterwalder N, Meisel A, Meisel C
J Neuroimmunol 2015 Jun 15;283:17-22. Epub 2015 Apr 7 doi: 10.1016/j.jneuroim.2015.03.023. [Epub ahead of print] PMID: 26004151
Dyck PJ, Taylor BV, Davies JL, Mauermann ML, Litchy WJ, Klein CJ, Dyck PJ
Muscle Nerve 2015 Oct;52(4):488-97. Epub 2015 Aug 13 doi: 10.1002/mus.24707. [Epub ahead of print] PMID: 25976871Free PMC Article
Vallat JM, Mathis S, Ghorab K, Milor MA, Richard L, Magy L
Eur Neurol 2015;73(5-6):294-302. Epub 2015 Apr 29 doi: 10.1159/000381767. [Epub ahead of print] PMID: 25925430
Névoret ML, Vinik AI
J Diabetes Complications 2015 Mar;29(2):313-7. Epub 2014 Nov 6 doi: 10.1016/j.jdiacomp.2014.10.012. [Epub ahead of print] PMID: 25466645
Kerasnoudis A, Pitarokoili K, Behrendt V, Gold R, Yoon MS
Muscle Nerve 2015 Jun;51(6):846-52. Epub 2015 Apr 24 doi: 10.1002/mus.24484. [Epub ahead of print] PMID: 25297575

Recent systematic reviews

Mehndiratta MM, Hughes RA, Pritchard J
Cochrane Database Syst Rev 2015 Aug 25;(8):CD003906. doi: 10.1002/14651858.CD003906.pub4. PMID: 26305459
Cocito D, Romagnolo A, Rosso M, Peci E, Lopiano L, Merola A
J Peripher Nerv Syst 2015 Mar;20(1):1-6. doi: 10.1111/jns.12108. PMID: 25864585
Rajabally YA, Cavanna AE
J Neurol Sci 2015 Jan 15;348(1-2):18-23. Epub 2014 Nov 13 doi: 10.1016/j.jns.2014.11.005. [Epub ahead of print] PMID: 25467139
Bright RJ, Wilkinson J, Coventry BJ
BMC Neurol 2014 Feb 7;14:26. doi: 10.1186/1471-2377-14-26. [Epub ahead of print] PMID: 24507546Free PMC Article
Dalakas MC; Medscape
Nat Rev Neurol 2011 Aug 16;7(9):507-17. doi: 10.1038/nrneurol.2011.121. [Epub ahead of print] PMID: 21844897

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