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Results: 1 to 20 of 52

1.

Cause of Death

The circumstance or condition that results in the death of a living being. (NCI) [from NCI]

MedGen UID:
40147
Concept ID:
C0007465
Finding
2.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
3.

Complication Aspects

Used with diseases to indicate conditions that co-exist or follow, i.e., co-existing diseases, complications, or sequelae. [from MeSH]

MedGen UID:
223946
Concept ID:
C1171258
Pathologic Function
4.

Infection

Unknown contamination with disease-producing germs. [from HHCC]

MedGen UID:
43874
Concept ID:
C0021311
Disease or Syndrome
5.

Histoplasmosis

Histoplasmosis is a disease caused by a fungus (or mold.) The fungus is common in the eastern and central United States. It grows in soil and material contaminated with bat or bird droppings. You get infected by breathing the fungal spores. You cannot get the infection from someone else. Histoplasmosis is often mild, with no symptoms. If you do get sick, it usually affects your lungs. Symptoms include feeling ill, fever, chest pains, and a dry cough. In severe cases, histoplasmosis spreads to other organs; this is called disseminated disease. Disseminated disease is more common in infants, young children, seniors, and people with immune system problems. Tests for histoplasmosis include blood or urine tests and tissue samples. Chest x-rays and CT scans may also help to diagnose it. Mild cases usually get better without treatment. Treatment of severe or chronic cases is with antifungal drugs. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
42468
Concept ID:
C0019655
Disease or Syndrome
6.

Necrosis

A permanent cessation of all vital functions of a tissue. [GOC:dph] [from GO]

MedGen UID:
10199
Concept ID:
C0027540
Pathologic Function
7.

Mycosis

If you have ever had athlete's foot or a yeast infection, you can blame a fungus. A fungus is a primitive organism. Mushrooms, mold and mildew are examples. Fungi live in air, in soil, on plants and in water. Some live in the human body. Only about half of all types of fungi are harmful. Some fungi reproduce through tiny spores in the air. You can inhale the spores or they can land on you. As a result, fungal infections often start in the lungs or on the skin. You are more likely to get a fungal infection if you have a weakened immune system or take antibiotics. Fungi can be difficult to kill. For skin and nail infections, you can apply medicine directly to the infected area. Oral antifungal medicines are also available for serious infections. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
6486
Concept ID:
C0026946
Disease or Syndrome
8.

Arthritis

If you feel pain and stiffness in your body or have trouble moving around, you might have arthritis. Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Over time, a swollen joint can become severely damaged. Some kinds of arthritis can also cause problems in your organs, such as your eyes or skin. Types of arthritis include: -Osteoarthritis is the most common type of arthritis. It's often related to aging or to an injury. -Autoimmune arthritis happens when your body's immune system attacks healthy cells in your body by mistake. Rheumatoid arthritis is the most common form of this kind of arthritis. Juvenile rheumatoid arthritis is a form of the disease that happens in children. -Infectious arthritis is an infection that has spread from another part of the body to the joint. -Psoriatic arthritis affects people with psoriasis. -Gout is a painful type of arthritis that happens when too much uric acid builds up in the body. It often starts in the big toe. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases.  [from MedlinePlus]

MedGen UID:
2043
Concept ID:
C0003864
Disease or Syndrome
9.

Histoplasmosis

MedGen UID:
799301
Concept ID:
CN204943
Disease or Syndrome
10.

Related

MedGen UID:
619805
Concept ID:
C0445223
Finding
11.

Rheumatoid arthritis

Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, as well as atrophy and rarefaction of bony structures. [from HPO]

MedGen UID:
504816
Concept ID:
CN001255
Finding
12.

Arthritis

Inflammation of a joint. [from HPO]

MedGen UID:
504815
Concept ID:
CN001254
Finding
13.

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Group of systemic vasculitis with a strong association with ANCA. The disorders are characterized by necrotizing inflammation of small and medium size vessels, with little or no immune-complex deposits in vessel walls. [from MeSH]

MedGen UID:
403453
Concept ID:
C2717865
Disease or Syndrome
14.

Oncolysis

The lysis (breakdown) of cancer cells. This can be caused by chemical or physical means (for example, strong detergents or high-energy sound waves) or by infection with a strain of virus that can lyse cells. [from NCI]

MedGen UID:
90709
Concept ID:
C0333516
Neoplastic Process
15.

Infantile neuroaxonal dystrophy

PLA2G6-associated neurodegeneration (PLAN) comprises a continuum of three phenotypes with overlapping clinical and radiologic features: Classic infantile neuroaxonal dystrophy (INAD). Atypical neuroaxonal dystrophy (atypical NAD). PLA2G6-related dystonia-parkinsonism. INAD usually begins between ages six months and three years with developmental regression, hypotonia, progressive psychomotor delay, and progressive spastic tetraparesis. Strabismus, nystagmus, and optic atrophy are common. Disease progression is rapid. Many affected children never learn to walk or lose the ability shortly after attaining it. Severe spasticity, progressive cognitive decline, and visual impairment typically result in death during the first decade. Atypical NAD shows more phenotypic variability than INAD. In general, onset is in early childhood but can be as late as the end of the second decade. The presenting signs may be gait instability or ataxia (as in the classic form) or speech delay and autistic features, which are sometimes the only evidence of disease for a year or more. The course is fairly stable during early childhood and resembles static encephalopathy but is followed by neurologic deterioration between ages seven and 12 years. PLA2G6-related dystonia-parkinsonism presents with subacute onset of dystonia-parkinsonism in late adolescence/early adulthood. Other findings are eye movement abnormalities, pyramidal tract signs, and marked cognitive decline. [from GeneReviews]

MedGen UID:
82852
Concept ID:
C0270724
Disease or Syndrome
16.

Hemorrhage

Bleeding is the loss of blood. It can happen inside or outside the body. Bleeding can be a reaction to a cut or other wound. It can also result from an injury to internal organs. There are many situations in which you might bleed. A bruise is bleeding under the skin. Some strokes are caused by bleeding in the brain. Other bleeding, such as gastrointestinal bleeding, coughing up blood, or vaginal bleeding, can be a symptom of a disease. Normally, when you bleed, your blood forms clots to stop the bleeding. Severe bleeding may require first aid or a trip to the emergency room. If you have a bleeding disorder, your blood does not form clots normally.  [from MedlinePlus]

MedGen UID:
5503
Concept ID:
C0019080
Pathologic Function
17.

Rheumatoid arthritis

Rheumatoid arthritis is an inflammatory disease, primarily of the joints, with autoimmune features and a complex genetic component. [from OMIM]

MedGen UID:
2078
Concept ID:
C0003873
Disease or Syndrome
18.

Immunomodulators

agents of both drug and biological origin often used in immunotherapy to stimulate, potentiate, or depress the immune response; also used to inhibit or enhance specific subclasses of immunocytes. [from CRISP]

MedGen UID:
282900
Concept ID:
C1527392
Pharmacologic Substance
19.

Enthesopathy

Disorder occurring at the site of insertion of tendons or ligaments into bones or joint capsules [from SNOMED CT]

MedGen UID:
66909
Concept ID:
C0242490
Disease or Syndrome
20.

Fatal Outcome

Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept. [from MeSH]

MedGen UID:
61558
Concept ID:
C0206277
Pathologic Function

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