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Sciatica

MedGen UID:
19893
Concept ID:
C0036396
Sign or Symptom
Synonyms: Neuralgia, Sciatic; Neuralgias, Sciatic; Sciatic Neuralgia; Sciatic Neuralgias
SNOMED CT: Sciatica neuralgia (23056005); Sciatica (23056005); Neuralgia-neuritis of sciatic nerve (23056005); Sciatic neuralgia (23056005)
 
HPO: HP:0011868

Definition

Sciatica is a symptom of a problem with the sciatic nerve, the largest nerve in the body. It controls muscles in the back of your knee and lower leg and provides feeling to the back of your thigh, part of your lower leg, and the sole of your foot. When you have sciatica, you have pain, weakness, numbness, or tingling. It can start in the lower back and extend down your leg to your calf, foot, or even your toes. It's usually on only one side of your body. Causes of sciatica include. -A ruptured intervertebral disk. -Narrowing of the spinal canal that puts pressure on the nerve, called spinal stenosis. -An injury such as a pelvic fracture. In many cases no cause can be found. Sometimes sciatica goes away on its own. Treatment, if needed, depends on the cause of the problem. It may include exercises, medicines, and surgery.  [from MedlinePlus]

Recent clinical studies

Etiology

Skorupska E, Rychlik M, Pawelec W, Bednarek A, Samborski W
BMC Res Notes 2014 Sep 9;7:620. doi: 10.1186/1756-0500-7-620. [Epub ahead of print] PMID: 25201416Free PMC Article
Bucknor MD, Steinbach LS, Saloner D, Chin CT
J Neurosurg 2014 Aug;121(2):408-14. Epub 2014 May 30 doi: 10.3171/2014.4.JNS13940. [Epub ahead of print] PMID: 24878283
el Barzouhi A, Vleggeert-Lankamp CL, Lycklama à Nijeholt GJ, Van der Kallen BF, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Nov 1;14(11):2598-607. Epub 2014 Feb 21 doi: 10.1016/j.spinee.2014.02.028. [Epub ahead of print] PMID: 24561397
Cook CE, Taylor J, Wright A, Milosavljevic S, Goode A, Whitford M
Physiother Res Int 2014 Jun;19(2):65-78. Epub 2013 Dec 11 doi: 10.1002/pri.1572. [Epub ahead of print] PMID: 24327326
el Barzouhi A, Vleggeert-Lankamp CL, van der Kallen BF, Lycklama à Nijeholt GJ, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Feb 1;14(2):225-33. Epub 2013 Nov 13 doi: 10.1016/j.spinee.2013.08.058. [Epub ahead of print] PMID: 24239802

Diagnosis

Skorupska E, Rychlik M, Pawelec W, Bednarek A, Samborski W
BMC Res Notes 2014 Sep 9;7:620. doi: 10.1186/1756-0500-7-620. [Epub ahead of print] PMID: 25201416Free PMC Article
Bucknor MD, Steinbach LS, Saloner D, Chin CT
J Neurosurg 2014 Aug;121(2):408-14. Epub 2014 May 30 doi: 10.3171/2014.4.JNS13940. [Epub ahead of print] PMID: 24878283
Savage NJ, Fritz JM, Thackeray A
J Orthop Sports Phys Ther 2014 Jul;44(7):508-17. Epub 2014 May 22 doi: 10.2519/jospt.2014.5002. [Epub ahead of print] PMID: 24853922
Cook CE, Taylor J, Wright A, Milosavljevic S, Goode A, Whitford M
Physiother Res Int 2014 Jun;19(2):65-78. Epub 2013 Dec 11 doi: 10.1002/pri.1572. [Epub ahead of print] PMID: 24327326
el Barzouhi A, Vleggeert-Lankamp CL, van der Kallen BF, Lycklama à Nijeholt GJ, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Feb 1;14(2):225-33. Epub 2013 Nov 13 doi: 10.1016/j.spinee.2013.08.058. [Epub ahead of print] PMID: 24239802

Therapy

Savage NJ, Fritz JM, Thackeray A
J Orthop Sports Phys Ther 2014 Jul;44(7):508-17. Epub 2014 May 22 doi: 10.2519/jospt.2014.5002. [Epub ahead of print] PMID: 24853922
Fitzsimmons D, Phillips CJ, Bennett H, Jones M, Williams N, Lewis R, Sutton A, Matar HE, Din N, Burton K, Nafees S, Hendry M, Rickard I, Wilkinson C
Pain 2014 Jul;155(7):1318-27. Epub 2014 Apr 13 doi: 10.1016/j.pain.2014.04.008. [Epub ahead of print] PMID: 24726924
el Barzouhi A, Vleggeert-Lankamp CL, Lycklama à Nijeholt GJ, Van der Kallen BF, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Nov 1;14(11):2598-607. Epub 2014 Feb 21 doi: 10.1016/j.spinee.2014.02.028. [Epub ahead of print] PMID: 24561397
el Barzouhi A, Vleggeert-Lankamp CL, van der Kallen BF, Lycklama à Nijeholt GJ, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Feb 1;14(2):225-33. Epub 2013 Nov 13 doi: 10.1016/j.spinee.2013.08.058. [Epub ahead of print] PMID: 24239802
Grøvle L, Haugen AJ, Keller A, Ntvig B, Brox JI, Grotle M
Spine J 2013 Dec;13(12):1849-57. Epub 2013 Sep 21 doi: 10.1016/j.spinee.2013.07.433. [Epub ahead of print] PMID: 24060231

Prognosis

Savage NJ, Fritz JM, Thackeray A
J Orthop Sports Phys Ther 2014 Jul;44(7):508-17. Epub 2014 May 22 doi: 10.2519/jospt.2014.5002. [Epub ahead of print] PMID: 24853922
el Barzouhi A, Vleggeert-Lankamp CL, Lycklama à Nijeholt GJ, Van der Kallen BF, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Nov 1;14(11):2598-607. Epub 2014 Feb 21 doi: 10.1016/j.spinee.2014.02.028. [Epub ahead of print] PMID: 24561397
Cook CE, Taylor J, Wright A, Milosavljevic S, Goode A, Whitford M
Physiother Res Int 2014 Jun;19(2):65-78. Epub 2013 Dec 11 doi: 10.1002/pri.1572. [Epub ahead of print] PMID: 24327326
el Barzouhi A, Vleggeert-Lankamp CL, van der Kallen BF, Lycklama à Nijeholt GJ, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Feb 1;14(2):225-33. Epub 2013 Nov 13 doi: 10.1016/j.spinee.2013.08.058. [Epub ahead of print] PMID: 24239802
Grøvle L, Haugen AJ, Keller A, Ntvig B, Brox JI, Grotle M
Spine J 2013 Dec;13(12):1849-57. Epub 2013 Sep 21 doi: 10.1016/j.spinee.2013.07.433. [Epub ahead of print] PMID: 24060231

Clinical prediction guides

Skorupska E, Rychlik M, Pawelec W, Bednarek A, Samborski W
BMC Res Notes 2014 Sep 9;7:620. doi: 10.1186/1756-0500-7-620. [Epub ahead of print] PMID: 25201416Free PMC Article
Savage NJ, Fritz JM, Thackeray A
J Orthop Sports Phys Ther 2014 Jul;44(7):508-17. Epub 2014 May 22 doi: 10.2519/jospt.2014.5002. [Epub ahead of print] PMID: 24853922
el Barzouhi A, Vleggeert-Lankamp CL, Lycklama à Nijeholt GJ, Van der Kallen BF, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Nov 1;14(11):2598-607. Epub 2014 Feb 21 doi: 10.1016/j.spinee.2014.02.028. [Epub ahead of print] PMID: 24561397
Cook CE, Taylor J, Wright A, Milosavljevic S, Goode A, Whitford M
Physiother Res Int 2014 Jun;19(2):65-78. Epub 2013 Dec 11 doi: 10.1002/pri.1572. [Epub ahead of print] PMID: 24327326
el Barzouhi A, Vleggeert-Lankamp CL, van der Kallen BF, Lycklama à Nijeholt GJ, van den Hout WB, Koes BW, Peul WC; Leiden–The Hague Spine Intervention Prognostic Study Group
Spine J 2014 Feb 1;14(2):225-33. Epub 2013 Nov 13 doi: 10.1016/j.spinee.2013.08.058. [Epub ahead of print] PMID: 24239802

Recent systematic reviews

Fitzsimmons D, Phillips CJ, Bennett H, Jones M, Williams N, Lewis R, Sutton A, Matar HE, Din N, Burton K, Nafees S, Hendry M, Rickard I, Wilkinson C
Pain 2014 Jul;155(7):1318-27. Epub 2014 Apr 13 doi: 10.1016/j.pain.2014.04.008. [Epub ahead of print] PMID: 24726924
Shiri R, Lallukka T, Karppinen J, Viikari-Juntura E
Am J Epidemiol 2014 Apr 15;179(8):929-37. Epub 2014 Feb 24 doi: 10.1093/aje/kwu007. [Epub ahead of print] PMID: 24569641
Cook CE, Taylor J, Wright A, Milosavljevic S, Goode A, Whitford M
Physiother Res Int 2014 Jun;19(2):65-78. Epub 2013 Dec 11 doi: 10.1002/pri.1572. [Epub ahead of print] PMID: 24327326
Wegner I, Widyahening IS, van Tulder MW, Blomberg SE, de Vet HC, Brønfort G, Bouter LM, van der Heijden GJ
Cochrane Database Syst Rev 2013 Aug 19;8:CD003010. doi: 10.1002/14651858.CD003010.pub5. PMID: 23959683
Verwoerd AJ, Luijsterburg PA, Lin CW, Jacobs WC, Koes BW, Verhagen AP
Eur J Pain 2013 Sep;17(8):1126-37. Epub 2013 Mar 14 doi: 10.1002/j.1532-2149.2013.00301.x. [Epub ahead of print] PMID: 23494852

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