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Results: 13

1.

Familial Mediterranean fever

Familial Mediterranean fever (FMF) comprises two phenotypes: type 1 and type 2. FMF type 1 is characterized by recurrent short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and, rarely, pericarditis and meningitis. The symptoms and severity vary among affected individuals, sometimes even among members of the same family. Amyloidosis, which can lead to renal failure, is the most severe complication. FMF type 2 is characterized by amyloidosis as the first clinical manifestation of FMF in an otherwise asymptomatic individual. [from GeneReviews]

MedGen UID:
45811
Concept ID:
C0031069
Disease or Syndrome
2.

Vasculitis

Vasculitis is an inflammation of the blood vessels. It happens when the body's immune system attacks the blood vessel by mistake. It can happen because of an infection, a medicine, or another disease. The cause is often unknown. Vasculitis can affect arteries, veins and capillaries. Arteries are vessels that carry blood from the heart to the body's organs. Veins are the vessels that carry blood back to the heart. Capillaries are tiny blood vessels that connect the small arteries and veins. . When a blood vessel becomes inflamed, it can: - Narrow, making it more difficult for blood to get through . - Close off completely so that blood can't get through . - Stretch and weaken so much that it bulges. The bulge is called an aneurysm. If it bursts, it can cause dangerous bleeding inside the body. Symptoms of vasculitis can vary, but usually include fever, swelling and a general sense of feeling ill. The main goal of treatment is to stop the inflammation. Steroids and other medicines to stop inflammation are often helpful. NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
12054
Concept ID:
C0042384
Disease or Syndrome
3.

Glomerulonephritis

A renal disorder characterized by damage in the glomeruli. It may be acute or chronic, focal or diffuse, and it may lead to renal failure. Causes include autoimmune disorders, infections, diabetes, and malignancies. [from NCI]

MedGen UID:
6616
Concept ID:
C0017658
Disease or Syndrome
4.

Fever

A fever is a body temperature that is higher than normal. It is not an illness. It is part of your body's defense against infection. Most bacteria and viruses that cause infections do well at the body's normal temperature (98.6 F). A slight fever can make it harder for them to survive. Fever also activates your body's immune system. Infections cause most fevers. There can be many other causes, including: - Medicines. - Heat exhaustion. - Cancers. - Autoimmune diseases. Treatment depends on the cause of your fever. Your health care provider may recommend using over-the-counter medicines such as acetaminophen or ibuprofen to lower a very high fever. Adults can also take aspirin, but children with fevers should not take aspirin. It is also important to drink enough liquids to prevent dehydration.  [from MedlinePlus]

MedGen UID:
5169
Concept ID:
C0015967
Finding
5.

Familial Mediterranean fever

Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent short episodes of fever and serositis resulting in pain in the abdomen, chest, joints and muscles. [from ORDO]

MedGen UID:
797520
Concept ID:
CN204415
Disease or Syndrome
6.

Glomerulonephritis

Inflammation of the renal glomeruli. [from HPO]

MedGen UID:
504340
Concept ID:
CN000099
Finding
7.

Vasculitis

MedGen UID:
369784
Concept ID:
C1963274
Finding
8.

Rapidly progressive

MedGen UID:
334665
Concept ID:
C1843027
Finding
9.

Rapidly progressive glomerulonephritis

MedGen UID:
113155
Concept ID:
C0221239
Disease or Syndrome
10.

Macroscopic hematuria

MedGen UID:
633103
Concept ID:
C0473237
Finding
11.

Small vessel vasculitis

A type of vasculitis (inflammation of blood vessel walls) that affects blood vessels that are smaller than arteries, i.e., arterioles, venules, and capilllaries. [from HPO]

MedGen UID:
489528
Concept ID:
CN167670
Finding
12.

Necrotizing glomerulonephritis

MedGen UID:
78699
Concept ID:
C0268750
Disease or Syndrome
13.

Purpuric rash

MedGen UID:
57495
Concept ID:
C0151882
Disease or Syndrome

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