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Post poliomyelitis syndrome

MedGen UID:
36363
Concept ID:
C0080040
Disease or Syndrome
Synonyms: Muscular Atrophies, Post-Poliomyelitis; Muscular Atrophies, Postpoliomyelitis; Muscular Atrophy, Post-Poliomyelitis; Muscular Atrophy, Postpoliomyelitis; Post Poliomyelitis Muscular Atrophy; Post Poliomyelitis Syndrome; Post-Polio Syndrome; Post-Polio Syndromes; Post-Poliomyelitis Muscular Atrophies; Post-Poliomyelitis Muscular Atrophy; Post-Poliomyelitis Syndrome; Postpoliomyelitis Muscular Atrophies; Postpoliomyelitis Muscular Atrophy; Postpoliomyelitis Syndrome
SNOMED CT: Post poliomyelitis syndrome (31097004); Postpolio syndrome (31097004); Postpolio muscular atrophy (31097004)
 

Definition

A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGPost poliomyelitis syndrome

Recent clinical studies

Etiology

Lira CA, Minozzo FC, Sousa BS, Vancini RL, Andrade Mdos S, Quadros AA, Oliveira AS, da Silva AC
J Bras Pneumol 2013 Jun-Aug;39(4):455-60. doi: 10.1590/S1806-37132013000400009. PMID: 24068267Free PMC Article
Trojan DA, Arnold DL, Shapiro S, Bar-Or A, Robinson A, Le Cruguel JP, Narayanan S, Tartaglia MC, Caramanos Z, Da Costa D
PM R 2009 May;1(5):442-9. doi: 10.1016/j.pmrj.2009.03.003. PMID: 19627931
Fordyce CB, Gagne D, Jalili F, Alatab S, Arnold DL, Da Costa D, Sawoszczuk S, Bodner C, Shapiro S, Collet JP, Robinson A, Le Cruguel JP, Lapierre Y, Bar-Or A, Trojan DA
J Neurol Sci 2008 Aug 15;271(1-2):80-6. Epub 2008 May 12 doi: 10.1016/j.jns.2008.03.015. [Epub ahead of print] PMID: 18474371
Perry J, Fontaine JD, Mulroy S
J Bone Joint Surg Am 1995 Aug;77(8):1148-53. PMID: 7642658
Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM
Arch Phys Med Rehabil 1994 Jul;75(7):770-7. PMID: 8024423

Diagnosis

Lira CA, Minozzo FC, Sousa BS, Vancini RL, Andrade Mdos S, Quadros AA, Oliveira AS, da Silva AC
J Bras Pneumol 2013 Jun-Aug;39(4):455-60. doi: 10.1590/S1806-37132013000400009. PMID: 24068267Free PMC Article
Quadros AA, Conde MT, Marin LF, Silva HC, Silva TM, Paula MB, Pereira RD, Ramos PE, Abe G, Oliveira AS
Arq Neuropsiquiatr 2012 Aug;70(8):571-3. PMID: 22899025
Ramaraj R
Br J Hosp Med (Lond) 2007 Dec;68(12):648-50. PMID: 18186398
Trojan DA, Cashman NR
Muscle Nerve 2005 Jan;31(1):6-19. doi: 10.1002/mus.20259. PMID: 15599928
Perry J, Fontaine JD, Mulroy S
J Bone Joint Surg Am 1995 Aug;77(8):1148-53. PMID: 7642658

Therapy

Allison DW, Gertsch JH, Mahan MA, Sheean GL, Brown JM
Neurodiagn J 2014 Mar;54(1):28-35. PMID: 24783748
Heim M, Yaacobi E, Azaria M
Clin Rehabil 1997 Nov;11(4):302-5. PMID: 9408670
Trojan DA, Cashman NR
Can J Neurol Sci 1995 Aug;22(3):223-7. PMID: 8529175
Dinsmore S, Dambrosia J, Dalakas MC
Ann N Y Acad Sci 1995 May 25;753:303-13. PMID: 7611639
Trojan DA, Cashman NR
Ann N Y Acad Sci 1995 May 25;753:285-95. PMID: 7611637

Prognosis

Trojan DA, Arnold DL, Shapiro S, Bar-Or A, Robinson A, Le Cruguel JP, Narayanan S, Tartaglia MC, Caramanos Z, Da Costa D
PM R 2009 May;1(5):442-9. doi: 10.1016/j.pmrj.2009.03.003. PMID: 19627931
Lin KH, Lim YW
Ann Acad Med Singapore 2005 Aug;34(7):447-9. PMID: 16123820
Heim M, Yaacobi E, Azaria M
Clin Rehabil 1997 Nov;11(4):302-5. PMID: 9408670
Trojan DA, Cashman NR
Can J Neurol Sci 1995 Aug;22(3):223-7. PMID: 8529175
Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM
Arch Phys Med Rehabil 1994 Jul;75(7):770-7. PMID: 8024423

Clinical prediction guides

Lira CA, Minozzo FC, Sousa BS, Vancini RL, Andrade Mdos S, Quadros AA, Oliveira AS, da Silva AC
J Bras Pneumol 2013 Jun-Aug;39(4):455-60. doi: 10.1590/S1806-37132013000400009. PMID: 24068267Free PMC Article
Trojan DA, Arnold DL, Shapiro S, Bar-Or A, Robinson A, Le Cruguel JP, Narayanan S, Tartaglia MC, Caramanos Z, Da Costa D
PM R 2009 May;1(5):442-9. doi: 10.1016/j.pmrj.2009.03.003. PMID: 19627931
Fordyce CB, Gagne D, Jalili F, Alatab S, Arnold DL, Da Costa D, Sawoszczuk S, Bodner C, Shapiro S, Collet JP, Robinson A, Le Cruguel JP, Lapierre Y, Bar-Or A, Trojan DA
J Neurol Sci 2008 Aug 15;271(1-2):80-6. Epub 2008 May 12 doi: 10.1016/j.jns.2008.03.015. [Epub ahead of print] PMID: 18474371
Perry J, Fontaine JD, Mulroy S
J Bone Joint Surg Am 1995 Aug;77(8):1148-53. PMID: 7642658
Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM
Arch Phys Med Rehabil 1994 Jul;75(7):770-7. PMID: 8024423

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