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Results: 1 to 20 of 34

1.

Insulin resistance

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. [from MeSH]

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
2.

Obesity

A disorder characterized by having a high amount of body fat. [from NCI]

MedGen UID:
18127
Concept ID:
C0028754
Disease or Syndrome
3.

Insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [from MeSH]

MedGen UID:
5827
Concept ID:
C0021641
Pharmacologic Substance
4.

Insulin resistance

`Increased resistance` (PATO:0001650) towards `insulin` (PRO:000009054), that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
504630
Concept ID:
CN000801
Finding
5.

Error occurred: cannot get document summary

ID:
449670

6.

Obesity

MedGen UID:
368429
Concept ID:
C1963185
Finding
7.

Insulin Sensitivity

MedGen UID:
452799
Concept ID:
C0920563
Pathologic Function
8.

Glucose

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. [from MeSH]

MedGen UID:
42238
Concept ID:
C0017725
Pharmacologic Substance
9.

Inflammation

A microscopic finding indicating the presence of acute, subacute or chronic inflammation in a tissue sample. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
10.

Hepatic steatosis

The presence of `steatosis` (MPATH:622) in the `liver` (FMA:7197). [from HPO]

MedGen UID:
427871
Concept ID:
CN001278
Finding
11.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
12.

Fatty degeneration

A morphologic finding indicating intracytoplasmic fat accumulation in the liver parenchyma. [from NCI]

MedGen UID:
57759
Concept ID:
C0152254
Pathologic Function
13.

Steatohepatitis

Inflammation of the liver related to lipid accumulation in fatty liver. [from MeSH]

MedGen UID:
398225
Concept ID:
C2711227
Disease or Syndrome
14.

Disorder of glucose metabolism

Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM. [from MeSH]

MedGen UID:
226229
Concept ID:
C1257958
Disease or Syndrome
15.

Disorder of hyperalimentation

An imbalanced nutritional status resulted from excessive intake of nutrients. Generally, overnutrition generates an energy imbalance between food consumption and energy expenditure leading to disorders such as OBESITY. [from MeSH]

MedGen UID:
219760
Concept ID:
C1257763
Disease or Syndrome
16.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
17.

Course of illness

Stages or progression of physical or mental disorders. Compare PROGNOSIS. [from PSY]

MedGen UID:
116631
Concept ID:
C0242656
Pathologic Function
18.

Overweight

BMI 25 [from CHV]

MedGen UID:
105424
Concept ID:
C0497406
Sign or Symptom
19.

Carbohydrate Metabolism

Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES. [from MeSH]

MedGen UID:
86224
Concept ID:
C0302820
Molecular Function
20.

Malnutrition

Disorders caused by nutritional imbalance, either overnutrition or undernutrition. [from MeSH]

MedGen UID:
56429
Concept ID:
C0162429
Disease or Syndrome

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