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Rabies

MedGen UID:
48308
Concept ID:
C0034494
Disease or Syndrome
Synonyms: Hydrophobia; Lyssa; Lyssas
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Describes a disorder that is not inherited.
SNOMED CT: Rabies (14168008); Hydrophobia (14168008); Lyssa (14168008)
 
Orphanet: ORPHA770

Definition

Rabies is a deadly animal disease caused by a virus. It can happen in wild animals, including raccoons, skunks, bats and foxes, or in dogs, cats or farm animals. People get it from the bite of an infected animal. . In people, symptoms of rabies include fever, headache and fatigue, then confusion, hallucinations and paralysis. Once the symptoms begin, the disease is usually fatal. A series of shots can prevent rabies in people exposed to the virus. You need to get them right away. If an animal bites you, wash the wound well; then get medical care. . To help prevent rabies: - Vaccinate your pet. Rabies vaccines are available for dogs, cats and farm animals. - Don't let pets roam. - Don't approach stray animals. Animals with rabies might be aggressive and vicious, or tired and weak. Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

Recent clinical studies

Etiology

Song M, Tang Q, Rayner S, Tao XY, Shen XX, Liang GD
Biomed Environ Sci 2014 Aug;27(8):627-32. doi: 10.3967/bes2014.095. PMID: 25189609
Webber BJ, Ayers KJ, Winterton BS, Yun HC, Cropper TL, Foster J Jr, Kren MC, Meek BY, Oliver TA, Hudson CM; Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2014 Aug 29;63(34):749-52. PMID: 25166925
Stahl JP, Gautret P, Ribadeau-Dumas F, Strady C, Le Moal G, Souala F, Maslin J, Fremont B, Bourhy H
Med Mal Infect 2014 Jul;44(7):292-301. Epub 2014 Jul 8 doi: 10.1016/j.medmal.2014.05.002. [Epub ahead of print] PMID: 25011930
Cliquet F, Picard-Meyer E, Robardet E
Expert Rev Anti Infect Ther 2014 Aug;12(8):905-8. Epub 2014 May 22 doi: 10.1586/14787210.2014.921570. [Epub ahead of print] PMID: 24847903
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934

Diagnosis

Voehl KM, Saturday GA
US Army Med Dep J 2014 Jul-Sep:27-32. PMID: 25074599
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934
Jemima EA, Manoharan S, Kumanan K
Arch Virol 2014 Aug;159(8):1987-93. Epub 2014 Mar 4 doi: 10.1007/s00705-014-2033-3. [Epub ahead of print] PMID: 24590567
Wiltzer L, Okada K, Yamaoka S, Larrous F, Kuusisto HV, Sugiyama M, Blondel D, Bourhy H, Jans DA, Ito N, Moseley GW
J Infect Dis 2014 Jun 1;209(11):1744-53. Epub 2013 Dec 23 doi: 10.1093/infdis/jit829. [Epub ahead of print] PMID: 24367042
Mani RS, Madhusudana SN, Mahadevan A, Reddy V, Belludi AY, Shankar SK
J Med Virol 2014 Oct;86(10):1804-12. Epub 2013 Oct 17 doi: 10.1002/jmv.23814. [Epub ahead of print] PMID: 24136727

Therapy

Sittichanbuncha Y, Chairat C, Sawanyawisuth K, Senthong V
Southeast Asian J Trop Med Public Health 2014 Sep;45(5):1048-52. PMID: 25417505
Stahl JP, Gautret P, Ribadeau-Dumas F, Strady C, Le Moal G, Souala F, Maslin J, Fremont B, Bourhy H
Med Mal Infect 2014 Jul;44(7):292-301. Epub 2014 Jul 8 doi: 10.1016/j.medmal.2014.05.002. [Epub ahead of print] PMID: 25011930
Houimel M
Hum Immunol 2014 Aug;75(8):745-55. Epub 2014 May 24 doi: 10.1016/j.humimm.2014.05.005. [Epub ahead of print] PMID: 24862931
Cliquet F, Picard-Meyer E, Robardet E
Expert Rev Anti Infect Ther 2014 Aug;12(8):905-8. Epub 2014 May 22 doi: 10.1586/14787210.2014.921570. [Epub ahead of print] PMID: 24847903
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934

Prognosis

Sittichanbuncha Y, Chairat C, Sawanyawisuth K, Senthong V
Southeast Asian J Trop Med Public Health 2014 Sep;45(5):1048-52. PMID: 25417505
Kashino W, Piyaphanee W, Kittitrakul C, Tangpukdee N, Sibunruang S, Lawpoolsri S, Yamashita H, Muangnoicharoen S, Silachamroon U, Tantawichien T
J Travel Med 2014 Jul-Aug;21(4):240-7. Epub 2014 May 20 doi: 10.1111/jtm.12124. [Epub ahead of print] PMID: 24845015
Robertson K, Feldman K
Vector Borne Zoonotic Dis 2014 Jun;14(6):454-60. Epub 2014 Apr 22 doi: 10.1089/vbz.2013.1305. [Epub ahead of print] PMID: 24754462
Pathak S, Horton DL, Lucas S, Brown D, Quaderi S, Polhill S, Walker D, Nastouli E, Núñez A, Wise EL, Fooks AR, Brown M
Virol J 2014 Apr 7;11:63. doi: 10.1186/1743-422X-11-63. [Epub ahead of print] PMID: 24708671Free PMC Article
de Souza A, Madhusudana SN
J Neurol Sci 2014 Apr 15;339(1-2):8-14. Epub 2014 Feb 20 doi: 10.1016/j.jns.2014.02.013. [Epub ahead of print] PMID: 24582283

Clinical prediction guides

Sittichanbuncha Y, Chairat C, Sawanyawisuth K, Senthong V
Southeast Asian J Trop Med Public Health 2014 Sep;45(5):1048-52. PMID: 25417505
Ameh VO, Dzikwi AA, Umoh JU
Glob J Health Sci 2014 Jun 12;6(5):226-40. doi: 10.5539/gjhs.v6n5p226. PMID: 25168987
Tohma K, Saito M, Kamigaki T, Tuason LT, Demetria CS, Orbina JR, Manalo DL, Miranda ME, Noguchi A, Inoue S, Suzuki A, Quiambao BP, Oshitani H
Infect Genet Evol 2014 Apr;23:86-94. Epub 2014 Feb 7 doi: 10.1016/j.meegid.2014.01.026. [Epub ahead of print] PMID: 24512808
Ward MP
Prev Vet Med 2014 Apr 1;114(1):11-20. Epub 2014 Jan 15 doi: 10.1016/j.prevetmed.2014.01.009. [Epub ahead of print] PMID: 24485277
Davlin SL, Lapiz SM, Miranda ME, Murray KO
Epidemiol Infect 2014 Jul;142(7):1476-85. Epub 2013 Oct 7 doi: 10.1017/S0950268813002513. [Epub ahead of print] PMID: 24093635

Recent systematic reviews

Morters MK, Restif O, Hampson K, Cleaveland S, Wood JL, Conlan AJ
J Anim Ecol 2013 Jan;82(1):6-14. Epub 2012 Sep 24 doi: 10.1111/j.1365-2656.2012.02033.x. [Epub ahead of print] PMID: 23004351Free PMC Article
Kakkar M, Venkataramanan V, Krishnan S, Chauhan RS, Abbas SS; Roadmap to Combat Zoonoses in India (RCZI) initiative
PLoS Negl Trop Dis 2012;6(8):e1748. Epub 2012 Aug 7 doi: 10.1371/journal.pntd.0001748. PMID: 22880139Free PMC Article
Davlin SL, Vonville HM
Vaccine 2012 May 21;30(24):3492-502. Epub 2012 Apr 3 doi: 10.1016/j.vaccine.2012.03.069. [Epub ahead of print] PMID: 22480924
Centers for Disease Control and Prevention
Ann Emerg Med 2010 Jul;56(1):64-7. PMID: 20648715
Sudarshan MK, Gangaboraiah B, Ravish HS, Narayana DH
Hum Vaccin 2010 Jul;6(7):562-5. Epub 2010 Jul 1 [Epub ahead of print] PMID: 20523131Free PMC Article

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