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Prostaglandins

MedGen UID:
18692
Concept ID:
C0033554
Pharmacologic Substance
Synonyms: Prostanoids
SNOMED CT: Prostaglandin (26351002); Prostaglandin product (350067007); PG - Prostaglandin (26351002)
 

Definition

One of several hormone-like substances made by the body. Different PGs control blood pressure, contraction of smooth muscles, and other processes within tissues where they are made. Certain PGs are being studied as cancer biomarkers. [from NCI]

Recent clinical studies

Etiology

Schmitz T, Pourcelot AG, Moutafoff C, Biran V, Sibony O, Oury JF
PLoS One 2013;8(11):e80903. Epub 2013 Nov 19 doi: 10.1371/journal.pone.0080903. PMID: 24260505Free PMC Article
Motaze NV, Mbuagbaw L, Young T
Cochrane Database Syst Rev 2013 Nov 11;11:CD010087. doi: 10.1002/14651858.CD010087.pub2. PMID: 24218013
Małysz-Cymborska I, Ziecik AJ, Waclawik A, Andronowska A
Reprod Domest Anim 2013 Dec;48(6):1034-42. Epub 2013 Jul 22 doi: 10.1111/rda.12210. [Epub ahead of print] PMID: 23876032
Gerli S, Favilli A, Giordano C, Bini V, Di Renzo GC
J Obstet Gynaecol Res 2013 May;39(5):926-31. Epub 2013 Feb 4 doi: 10.1111/jog.12000. [Epub ahead of print] PMID: 23379910
Lopez MG, Silva BM, Joyner MJ, Casey DP
Eur J Appl Physiol 2013 Jun;113(6):1449-56. Epub 2012 Dec 19 doi: 10.1007/s00421-012-2570-y. [Epub ahead of print] PMID: 23250568

Diagnosis

Konstas AG, Quaranta L, Katsanos A, Riva I, Tsai JC, Giannopoulos T, Voudouragkaki IC, Paschalinou E, Floriani I, Haidich AB
Br J Ophthalmol 2013 Dec;97(12):1510-5. Epub 2013 May 16 doi: 10.1136/bjophthalmol-2012-303026. [Epub ahead of print] PMID: 23681371
Prasain JK, Arabshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S
J Chromatogr B Analyt Technol Biomed Life Sci 2013 Jan 15;913-914:161-8. Epub 2012 Dec 20 doi: 10.1016/j.jchromb.2012.12.009. [Epub ahead of print] PMID: 23314354Free PMC Article
Cunningham C, Skelly DT
J Neuroimmune Pharmacol 2012 Mar;7(1):60-73. Epub 2011 Sep 20 doi: 10.1007/s11481-011-9312-5. [Epub ahead of print] PMID: 21932048Free PMC Article
Dias A, Garcia C, Majewski M, Wallner G, McCallum RW, Poplawski C, Sarosiek J
Dig Dis Sci 2011 Nov;56(11):3220-5. Epub 2011 Jun 22 doi: 10.1007/s10620-011-1758-z. [Epub ahead of print] PMID: 21695403Free PMC Article
Daham K, Song WL, Lawson JA, Kupczyk M, Gülich A, Dahlén SE, FitzGerald GA, Dahlén B
Clin Exp Allergy 2011 Jan;41(1):36-45. Epub 2010 Sep 28 doi: 10.1111/j.1365-2222.2010.03617.x. [Epub ahead of print] PMID: 20880055

Therapy

Motaze NV, Mbuagbaw L, Young T
Cochrane Database Syst Rev 2013 Nov 11;11:CD010087. doi: 10.1002/14651858.CD010087.pub2. PMID: 24218013
Reina E, Ramos FA, Castellanos L, Aragón M, Ospina LF
J Pharm Pharmacol 2013 Nov;65(11):1643-52. doi: 10.1111/jphp.12138. PMID: 24118067
Agas D, Marchetti L, Capitani M, Sabbieti MG
Am J Physiol Endocrinol Metab 2013 Nov 15;305(10):E1185-94. Epub 2013 Sep 17 doi: 10.1152/ajpendo.00290.2013. [Epub ahead of print] PMID: 24045870
Gerli S, Favilli A, Giordano C, Bini V, Di Renzo GC
J Obstet Gynaecol Res 2013 May;39(5):926-31. Epub 2013 Feb 4 doi: 10.1111/jog.12000. [Epub ahead of print] PMID: 23379910
Lopez MG, Silva BM, Joyner MJ, Casey DP
Eur J Appl Physiol 2013 Jun;113(6):1449-56. Epub 2012 Dec 19 doi: 10.1007/s00421-012-2570-y. [Epub ahead of print] PMID: 23250568

Prognosis

Kim J, Lee S, Kim YM, Jeoung DI, Choe J
Mol Immunol 2013 Oct;55(3-4):418-23. Epub 2013 Apr 11 doi: 10.1016/j.molimm.2013.03.019. [Epub ahead of print] PMID: 23583086
Trappe TA, Liu SZ
J Appl Physiol (1985) 2013 Sep;115(6):909-19. Epub 2013 Mar 28 doi: 10.1152/japplphysiol.00061.2013. [Epub ahead of print] PMID: 23539318Free PMC Article
Favilli A, Acanfora MM, Bini V, Radicchi R, Di Renzo GC, Gerli S
J Matern Fetal Neonatal Med 2013 May;26(7):665-8. Epub 2012 Dec 12 doi: 10.3109/14767058.2012.746658. [Epub ahead of print] PMID: 23130593
Cavalcanti AB, De Vasconcelos CP, Perroni de Oliveira M, Rother ET, Ferraz L Jr
Cochrane Database Syst Rev 2011 Nov 9;(11):CD006006. doi: 10.1002/14651858.CD006006.pub2. PMID: 22071826
Martinez de Tejada B, Martillotti G, Lapaire O, Hoesli I, Irion O
J Matern Fetal Neonatal Med 2010 Sep;23(9):988-93. doi: 10.3109/14767050903443475. PMID: 19941444

Clinical prediction guides

Motaze NV, Mbuagbaw L, Young T
Cochrane Database Syst Rev 2013 Nov 11;11:CD010087. doi: 10.1002/14651858.CD010087.pub2. PMID: 24218013
Kim J, Lee S, Kim YM, Jeoung DI, Choe J
Mol Immunol 2013 Oct;55(3-4):418-23. Epub 2013 Apr 11 doi: 10.1016/j.molimm.2013.03.019. [Epub ahead of print] PMID: 23583086
Trappe TA, Liu SZ
J Appl Physiol (1985) 2013 Sep;115(6):909-19. Epub 2013 Mar 28 doi: 10.1152/japplphysiol.00061.2013. [Epub ahead of print] PMID: 23539318Free PMC Article
Gerli S, Favilli A, Giordano C, Bini V, Di Renzo GC
J Obstet Gynaecol Res 2013 May;39(5):926-31. Epub 2013 Feb 4 doi: 10.1111/jog.12000. [Epub ahead of print] PMID: 23379910
Hua R, Pease JE, Cheng W, Sooranna SR, Viney JM, Nelson SM, Myatt L, Bennett PR, Johnson MR
Am J Reprod Immunol 2013 Jan;69(1):21-32. Epub 2012 Oct 9 doi: 10.1111/aji.12025. [Epub ahead of print] PMID: 23043391

Recent systematic reviews

Motaze NV, Mbuagbaw L, Young T
Cochrane Database Syst Rev 2013 Nov 11;11:CD010087. doi: 10.1002/14651858.CD010087.pub2. PMID: 24218013
Tunçalp Ö, Hofmeyr GJ, Gülmezoglu AM
Cochrane Database Syst Rev 2012 Aug 15;8:CD000494. doi: 10.1002/14651858.CD000494.pub4. PMID: 22895917
Neeman E, Zmora O, Ben-Eliyahu S
Clin Cancer Res 2012 Sep 15;18(18):4895-902. Epub 2012 Jul 2 doi: 10.1158/1078-0432.CCR-12-1087. [Epub ahead of print] PMID: 22753587Free PMC Article
Cavalcanti AB, De Vasconcelos CP, Perroni de Oliveira M, Rother ET, Ferraz L Jr
Cochrane Database Syst Rev 2011 Nov 9;(11):CD006006. doi: 10.1002/14651858.CD006006.pub2. PMID: 22071826
Chen QJ, Hou SP, Meads C, Huang YM, Hong QQ, Zhu HP, Cheng LN; EBM-CONNECT Collaboration
Eur J Obstet Gynecol Reprod Biol 2011 Dec;159(2):247-54. Epub 2011 Jul 8 doi: 10.1016/j.ejogrb.2011.06.034. [Epub ahead of print] PMID: 21741747

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