Format

Send to:

Choose Destination

Links from PubMed

Genetic predisposition

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
Synonyms: Genetic Predisposition; Genetic Predisposition to Disease; Genetic Predispositions; Genetic Susceptibilities; Genetic Susceptibility; Predisposition, Genetic; Predispositions, Genetic; Susceptibilities, Genetic; Susceptibility, Genetic
SNOMED CT: Genetic predisposition (47708004)
 

Definition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

Professional guidelines

PubMed

Obstet Gynecol 2012 Jun;119(6):1318-9. doi: 10.1097/AOG.0b013e31825af3c6. PMID: 22617616

Recent clinical studies

Etiology

Zlatohlávek L, Hubáček JA, Vrablík M, Pejšová H, Lánská V, Češka R
Cent Eur J Public Health 2015 Nov;23 Suppl:S62-6. doi: 10.21101/cejph.a4191. PMID: 26849546
Park HY, Choi HJ, Hong YC
J Korean Med Sci 2015 Aug;30(8):1101-9. Epub 2015 Jul 15 doi: 10.3346/jkms.2015.30.8.1101. PMID: 26240488Free PMC Article
Masschelein E, Puype J, Broos S, Van Thienen R, Deldicque L, Lambrechts D, Hespel P, Thomis M
High Alt Med Biol 2015 Mar;16(1):34-42. Epub 2015 Mar 11 doi: 10.1089/ham.2014.1083. [Epub ahead of print] PMID: 25761120
Babushok DV, Bessler M
Best Pract Res Clin Haematol 2015 Mar;28(1):55-68. Epub 2014 Nov 12 doi: 10.1016/j.beha.2014.11.004. [Epub ahead of print] PMID: 25659730Free PMC Article
Eysturoy AN, Skov L, Debes NM
J Child Neurol 2015 Mar;30(3):320-5. Epub 2014 Aug 24 doi: 10.1177/0883073814538668. [Epub ahead of print] PMID: 25156665

Diagnosis

Park HY, Choi HJ, Hong YC
J Korean Med Sci 2015 Aug;30(8):1101-9. Epub 2015 Jul 15 doi: 10.3346/jkms.2015.30.8.1101. PMID: 26240488Free PMC Article
Masschelein E, Puype J, Broos S, Van Thienen R, Deldicque L, Lambrechts D, Hespel P, Thomis M
High Alt Med Biol 2015 Mar;16(1):34-42. Epub 2015 Mar 11 doi: 10.1089/ham.2014.1083. [Epub ahead of print] PMID: 25761120
Babushok DV, Bessler M
Best Pract Res Clin Haematol 2015 Mar;28(1):55-68. Epub 2014 Nov 12 doi: 10.1016/j.beha.2014.11.004. [Epub ahead of print] PMID: 25659730Free PMC Article
Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK
Am J Hypertens 2015 Jul;28(7):915-23. Epub 2014 Dec 17 doi: 10.1093/ajh/hpu242. [Epub ahead of print] PMID: 25523295Free PMC Article
Eysturoy AN, Skov L, Debes NM
J Child Neurol 2015 Mar;30(3):320-5. Epub 2014 Aug 24 doi: 10.1177/0883073814538668. [Epub ahead of print] PMID: 25156665

Therapy

Pinto N, Hawkins DS
Pediatr Blood Cancer 2016 Feb;63(2):189-90. Epub 2015 Oct 27 doi: 10.1002/pbc.25776. [Epub ahead of print] PMID: 26505490
Cuellar-Partida G, Lu Y, Kho PF, Hewitt AW, Wichmann HE, Yazar S, Stambolian D, Bailey-Wilson JE, Wojciechowski R, Wang JJ, Mitchell P, Mackey DA, MacGregor S
Genet Epidemiol 2016 Jan;40(1):66-72. Epub 2015 Oct 26 doi: 10.1002/gepi.21936. [Epub ahead of print] PMID: 26497973Free PMC Article
Reddy YN, Abraham G, Sundaram V, Reddy PP, Mathew M, Nagarajan P, Mehra N, Ramachandran A, Ali AA, Reddy YN
Saudi J Kidney Dis Transpl 2015 Nov;26(6):1113-20. doi: 10.4103/1319-2442.168558. PMID: 26586047
Babushok DV, Bessler M
Best Pract Res Clin Haematol 2015 Mar;28(1):55-68. Epub 2014 Nov 12 doi: 10.1016/j.beha.2014.11.004. [Epub ahead of print] PMID: 25659730Free PMC Article
Larsen SC, Ängquist L, Ahluwalia TS, Skaaby T, Roswall N, Tjønneland A, Halkjær J, Overvad K, Pedersen O, Hansen T, Linneberg A, Husemoen LL, Toft U, Heitmann BL, Sørensen TIa
Am J Clin Nutr 2014 Apr;99(4):957-65. Epub 2014 Feb 5 doi: 10.3945/ajcn.113.076596. [Epub ahead of print] PMID: 24500147

Prognosis

Vilander LM, Kaunisto MA, Pettilä V
BMC Nephrol 2015 Dec 2;16:197. doi: 10.1186/s12882-015-0190-6. [Epub ahead of print] PMID: 26627480Free PMC Article
Lu X, Huang J, Wang L, Chen S, Yang X, Li J, Cao J, Chen J, Li Y, Zhao L, Li H, Liu F, Huang C, Shen C, Shen J, Yu L, Xu L, Mu J, Wu X, Ji X, Guo D, Zhou Z, Yang Z, Wang R, Yang J, Yan W, Gu D
Hypertension 2015 Oct;66(4):786-92. Epub 2015 Aug 17 doi: 10.1161/HYPERTENSIONAHA.115.05961. [Epub ahead of print] PMID: 26283040
Park HY, Choi HJ, Hong YC
J Korean Med Sci 2015 Aug;30(8):1101-9. Epub 2015 Jul 15 doi: 10.3346/jkms.2015.30.8.1101. PMID: 26240488Free PMC Article
Huang T, Qi Q, Zheng Y, Ley SH, Manson JE, Hu FB, Qi L
Diabetes Care 2015 Jul;38(7):1306-11. Epub 2015 Apr 7 doi: 10.2337/dc14-3084. [Epub ahead of print] PMID: 25852209Free PMC Article
Masschelein E, Puype J, Broos S, Van Thienen R, Deldicque L, Lambrechts D, Hespel P, Thomis M
High Alt Med Biol 2015 Mar;16(1):34-42. Epub 2015 Mar 11 doi: 10.1089/ham.2014.1083. [Epub ahead of print] PMID: 25761120

Clinical prediction guides

Park HY, Choi HJ, Hong YC
J Korean Med Sci 2015 Aug;30(8):1101-9. Epub 2015 Jul 15 doi: 10.3346/jkms.2015.30.8.1101. PMID: 26240488Free PMC Article
Walker CG, Solis-Trapala I, Holzapfel C, Ambrosini GL, Fuller NR, Loos RJ, Hauner H, Caterson ID, Jebb SA
PLoS One 2015;10(7):e0131681. Epub 2015 Jul 8 doi: 10.1371/journal.pone.0131681. PMID: 26154605Free PMC Article
Huang T, Qi Q, Zheng Y, Ley SH, Manson JE, Hu FB, Qi L
Diabetes Care 2015 Jul;38(7):1306-11. Epub 2015 Apr 7 doi: 10.2337/dc14-3084. [Epub ahead of print] PMID: 25852209Free PMC Article
Masschelein E, Puype J, Broos S, Van Thienen R, Deldicque L, Lambrechts D, Hespel P, Thomis M
High Alt Med Biol 2015 Mar;16(1):34-42. Epub 2015 Mar 11 doi: 10.1089/ham.2014.1083. [Epub ahead of print] PMID: 25761120
Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK
Am J Hypertens 2015 Jul;28(7):915-23. Epub 2014 Dec 17 doi: 10.1093/ajh/hpu242. [Epub ahead of print] PMID: 25523295Free PMC Article

Recent systematic reviews

Vilander LM, Kaunisto MA, Pettilä V
BMC Nephrol 2015 Dec 2;16:197. doi: 10.1186/s12882-015-0190-6. [Epub ahead of print] PMID: 26627480Free PMC Article
Oldridge DA, Wood AC, Weichert-Leahey N, Crimmins I, Sussman R, Winter C, McDaniel LD, Diamond M, Hart LS, Zhu S, Durbin AD, Abraham BJ, Anders L, Tian L, Zhang S, Wei JS, Khan J, Bramlett K, Rahman N, Capasso M, Iolascon A, Gerhard DS, Guidry Auvil JM, Young RA, Hakonarson H, Diskin SJ, Look AT, Maris JM
Nature 2015 Dec 17;528(7582):418-21. Epub 2015 Nov 11 doi: 10.1038/nature15540. [Epub ahead of print] PMID: 26560027Free PMC Article
Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hopper JL, Provenzano E, Apicella C, Wesseling J, Cornelissen S, Keeman R, Fasching PA, Jud SM, Ekici AB, Beckmann MW, Kerin MJ, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T, Laurent-Puig P, Kerbrat P, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Benitez J, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Lochmann M, Brauch H, Fischer HP, Ko YD; GENICA Network, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Bogdanova NV, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Chenevix-Trench G, Investigators K, Lambrechts D, Weltens C, Van Limbergen E, Hatse S, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Volorio S, Giles GG, Severi G, Baglietto L, McLean CA, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Kristensen V, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devillee P, Tollenaar RA, Seynaeve CM, Kriege M, Figueroa J, Chanock SJ, Sherman ME, Hooning MJ, Hollestelle A, van den Ouweland AM, van Deurzen CH, Li J, Czene K, Humphreys K, Cox A, Cross SS, Reed MW, Shah M, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Couch FJ, Hallberg E, González-Neira A, Pita G, Alonso MR, Tessier DC, Vincent D, Bacot F, Bolla MK, Wang Q, Dennis J, Michailidou K, Dunning AM, Hall P, Easton D, Pharoah P, Schmidt MK, Tomlinson I, Garcia-Closas M
PLoS Genet 2014 Apr;10(4):e1004285. Epub 2014 Apr 17 doi: 10.1371/journal.pgen.1004285. PMID: 24743323Free PMC Article
Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; CARDIoGRAM
Hypertension 2013 May;61(5):995-1001. Epub 2013 Mar 11 doi: 10.1161/HYPERTENSIONAHA.111.00275. [Epub ahead of print] PMID: 23478099Free PMC Article
Qi Q, Forman JP, Jensen MK, Flint A, Curhan GC, Rimm EB, Hu FB, Qi L
Diabetes 2012 Nov;61(11):3026-32. Epub 2012 Jul 24 doi: 10.2337/db12-0225. [Epub ahead of print] PMID: 22829449Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...