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gamma-Tocopherol

MedGen UID:
5315
Concept ID:
C0017054
Pharmacologic Substance
Synonyms: 3,4-Dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
SNOMED CT: Gamma tocopherol (116778000); gamma-Tocopherol preparation (45888006)
 

Definition

A natural tocopherol with less antioxidant activity than ALPHA-TOCOPHEROL. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. As in BETA-TOCOPHEROL, it also has three methyl groups on the 6-chromanol nucleus but at different sites. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGgamma-Tocopherol

Recent clinical studies

Etiology

Cui R, Liu ZQ, Xu Q
PLoS One 2014;9(3):e93044. Epub 2014 Mar 25 doi: 10.1371/journal.pone.0093044. PMID: 24667740Free PMC Article
Marchese ME, Kumar R, Colangelo LA, Avila PC, Jacobs DR Jr, Gross M, Sood A, Liu K, Cook-Mills JM
Respir Res 2014 Mar 15;15:31. doi: 10.1186/1465-9921-15-31. [Epub ahead of print] PMID: 24629024Free PMC Article
Grebenstein N, Schumacher M, Graeve L, Frank J
Mol Nutr Food Res 2014 May;58(5):1052-60. Epub 2014 Jan 13 doi: 10.1002/mnfr.201300756. [Epub ahead of print] PMID: 24420818
Hernandez ML, Wagner JG, Kala A, Mills K, Wells HB, Alexis NE, Lay JC, Jiang Q, Zhang H, Zhou H, Peden DB
Free Radic Biol Med 2013 Jul;60:56-62. Epub 2013 Feb 9 doi: 10.1016/j.freeradbiomed.2013.02.001. [Epub ahead of print] PMID: 23402870Free PMC Article
Prokopowicz A, Sobczak A, Szuła M, Anczyk E, Kurek J, Olszowy Z, Radek M, Pawlas N, Ochota P, Szołtysek-Bołdys I
Occup Environ Med 2013 Jun;70(6):365-71. Epub 2013 Feb 1 doi: 10.1136/oemed-2012-100979. [Epub ahead of print] PMID: 23378446

Diagnosis

Marchese ME, Kumar R, Colangelo LA, Avila PC, Jacobs DR Jr, Gross M, Sood A, Liu K, Cook-Mills JM
Respir Res 2014 Mar 15;15:31. doi: 10.1186/1465-9921-15-31. [Epub ahead of print] PMID: 24629024Free PMC Article
Bauer SR, Richman EL, Sosa E, Weinberg V, Song X, Witte JS, Carroll PR, Chan JM
Prostate 2013 Dec;73(16):1786-95. Epub 2013 Aug 29 doi: 10.1002/pros.22717. [Epub ahead of print] PMID: 24038157
Geiser M, Lay JC, Bennett WD, Zhou H, Wang X, Peden DB, Alexis NE
J Innate Immun 2013;5(6):613-24. Epub 2013 May 8 doi: 10.1159/000350234. [Epub ahead of print] PMID: 23689260Free PMC Article
Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund LO, Simmons A, Mecocci P; AddNeuroMed consortium
J Intern Med 2013 Jun;273(6):602-21. Epub 2013 Feb 28 doi: 10.1111/joim.12037. [Epub ahead of print] PMID: 23343471
Yang WC, Regnier FE, Jiang Q, Adamec J
J Chromatogr A 2010 Jan 29;1217(5):667-75. Epub 2009 Dec 4 doi: 10.1016/j.chroma.2009.12.002. [Epub ahead of print] PMID: 20006340Free PMC Article

Therapy

Marchese ME, Kumar R, Colangelo LA, Avila PC, Jacobs DR Jr, Gross M, Sood A, Liu K, Cook-Mills JM
Respir Res 2014 Mar 15;15:31. doi: 10.1186/1465-9921-15-31. [Epub ahead of print] PMID: 24629024Free PMC Article
Shamim AA, Kabir A, Merrill RD, Ali H, Rashid M, Schulze K, Labrique A, West KP Jr, Christian P
Public Health Nutr 2013 Aug;16(8):1354-61. Epub 2013 Mar 7 doi: 10.1017/S1368980013000475. [Epub ahead of print] PMID: 23469947
Hernandez ML, Wagner JG, Kala A, Mills K, Wells HB, Alexis NE, Lay JC, Jiang Q, Zhang H, Zhou H, Peden DB
Free Radic Biol Med 2013 Jul;60:56-62. Epub 2013 Feb 9 doi: 10.1016/j.freeradbiomed.2013.02.001. [Epub ahead of print] PMID: 23402870Free PMC Article
Prokopowicz A, Sobczak A, Szuła M, Anczyk E, Kurek J, Olszowy Z, Radek M, Pawlas N, Ochota P, Szołtysek-Bołdys I
Occup Environ Med 2013 Jun;70(6):365-71. Epub 2013 Feb 1 doi: 10.1136/oemed-2012-100979. [Epub ahead of print] PMID: 23378446
Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund LO, Simmons A, Mecocci P; AddNeuroMed consortium
J Intern Med 2013 Jun;273(6):602-21. Epub 2013 Feb 28 doi: 10.1111/joim.12037. [Epub ahead of print] PMID: 23343471

Prognosis

Marchese ME, Kumar R, Colangelo LA, Avila PC, Jacobs DR Jr, Gross M, Sood A, Liu K, Cook-Mills JM
Respir Res 2014 Mar 15;15:31. doi: 10.1186/1465-9921-15-31. [Epub ahead of print] PMID: 24629024Free PMC Article
Prokopowicz A, Sobczak A, Szuła M, Anczyk E, Kurek J, Olszowy Z, Radek M, Pawlas N, Ochota P, Szołtysek-Bołdys I
Occup Environ Med 2013 Jun;70(6):365-71. Epub 2013 Feb 1 doi: 10.1136/oemed-2012-100979. [Epub ahead of print] PMID: 23378446
Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund LO, Simmons A, Mecocci P; AddNeuroMed consortium
J Intern Med 2013 Jun;273(6):602-21. Epub 2013 Feb 28 doi: 10.1111/joim.12037. [Epub ahead of print] PMID: 23343471
Tasanarong A, Vohakiat A, Hutayanon P, Piyayotai D
Nephrol Dial Transplant 2013 Feb;28(2):337-44. Epub 2013 Jan 12 doi: 10.1093/ndt/gfs525. [Epub ahead of print] PMID: 23314316
Nagao M, Moriyama Y, Yamagishi K, Iso H, Tamakoshi A; JACC Study Group
J Epidemiol 2012;22(5):402-10. Epub 2012 May 19 [Epub ahead of print] PMID: 22672959Free PMC Article

Clinical prediction guides

Grebenstein N, Schumacher M, Graeve L, Frank J
Mol Nutr Food Res 2014 May;58(5):1052-60. Epub 2014 Jan 13 doi: 10.1002/mnfr.201300756. [Epub ahead of print] PMID: 24420818
Prokopowicz A, Sobczak A, Szuła M, Anczyk E, Kurek J, Olszowy Z, Radek M, Pawlas N, Ochota P, Szołtysek-Bołdys I
Occup Environ Med 2013 Jun;70(6):365-71. Epub 2013 Feb 1 doi: 10.1136/oemed-2012-100979. [Epub ahead of print] PMID: 23378446
Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund LO, Simmons A, Mecocci P; AddNeuroMed consortium
J Intern Med 2013 Jun;273(6):602-21. Epub 2013 Feb 28 doi: 10.1111/joim.12037. [Epub ahead of print] PMID: 23343471
Tasanarong A, Vohakiat A, Hutayanon P, Piyayotai D
Nephrol Dial Transplant 2013 Feb;28(2):337-44. Epub 2013 Jan 12 doi: 10.1093/ndt/gfs525. [Epub ahead of print] PMID: 23314316
Torricelli P, Caraglia M, Abbruzzese A, Beninati S
Amino Acids 2013 Jan;44(1):45-51. Epub 2012 Mar 30 doi: 10.1007/s00726-012-1278-y. [Epub ahead of print] PMID: 22460364

Recent systematic reviews

Cui R, Liu ZQ, Xu Q
PLoS One 2014;9(3):e93044. Epub 2014 Mar 25 doi: 10.1371/journal.pone.0093044. PMID: 24667740Free PMC Article
Li P, Zhang H, Chen J, Shi Y, Cai J, Yang J, Wu Y
Int J Cancer 2014 Sep 15;135(6):1444-53. Epub 2014 Mar 4 doi: 10.1002/ijc.28777. [Epub ahead of print] PMID: 24510802
Vance TM, Su J, Fontham ET, Koo SI, Chun OK
Nutr Cancer 2013;65(6):793-801. doi: 10.1080/01635581.2013.806672. PMID: 23909722Free PMC Article
Patel CJ, Cullen MR, Ioannidis JP, Butte AJ
Int J Epidemiol 2012 Jun;41(3):828-43. Epub 2012 Mar 15 doi: 10.1093/ije/dys003. [Epub ahead of print] PMID: 22421054Free PMC Article
Major JM, Yu K, Wheeler W, Zhang H, Cornelis MC, Wright ME, Yeager M, Snyder K, Weinstein SJ, Mondul A, Eliassen H, Purdue M, Hazra A, McCarty CA, Hendrickson S, Virtamo J, Hunter D, Chanock S, Kraft P, Albanes D
Hum Mol Genet 2011 Oct 1;20(19):3876-83. Epub 2011 Jul 5 doi: 10.1093/hmg/ddr296. [Epub ahead of print] PMID: 21729881Free PMC Article

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