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Hodgkin lymphoma, classical

MedGen UID:
798528
Concept ID:
CN204952
Disease or Syndrome
Synonyms: Classical Hodgkin disease; Classical Hodgkin's disease; Classical Hodgkin's lymphoma
Modes of inheritance:
Inheritance with unknown mechanism
MedGen UID:
831588
Concept ID:
CN227389
Intellectual Product
Describes an inherited disorder with unknown mode of inheritance.
 
Orphanet: ORPHA391

Definition

Classical Hodgkin lymphoma (CHL) is a B-cell lymphoma characterized histologically by the presence of large mononuclear Hodgkin cells and multinucleated Reed-Sternberg (HRS) cells. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGHodgkin lymphoma, classical

Recent clinical studies

Etiology

Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS
Cancer 2014 Jul 15;120(14):2122-9. Epub 2014 Apr 7 doi: 10.1002/cncr.28698. [Epub ahead of print] PMID: 24711253
Leventaki V, Drakos E, Karanikou M, Psatha K, Lin P, Schlette E, Eliopoulos A, Vassilakopoulos TP, Papadaki H, Patsouris E, Medeiros LJ, Rassidakis GZ
Hum Pathol 2014 Mar;45(3):565-72. Epub 2013 Oct 31 doi: 10.1016/j.humpath.2013.10.024. [Epub ahead of print] PMID: 24457077
Florentine BD, Cohen AN
Diagn Cytopathol 2014 Mar;42(3):238-41. Epub 2011 Sep 30 doi: 10.1002/dc.21829. [Epub ahead of print] PMID: 21965120
Xavier AC, Armeson KE, Hill EG, Costa LJ
Cancer 2013 Sep 15;119(18):3385-92. Epub 2013 Jun 24 doi: 10.1002/cncr.28194. [Epub ahead of print] PMID: 23797978Free PMC Article
Hartmann S, Jakobus C, Rengstl B, Döring C, Newrzela S, Brodt HR, Wolf T, Hansmann ML
Mod Pathol 2013 May;26(5):648-57. Epub 2013 Jan 11 doi: 10.1038/modpathol.2012.217. [Epub ahead of print] PMID: 23307058

Diagnosis

Hollman-Hewgley D, Lazare M, Bordwell A, Zebadua E, Tripathi P, Ross AS, Fisher D, Adams A, Bouman D, O'Malley DP, Weiss LM
Am J Surg Pathol 2014 Sep;38(9):1193-202. doi: 10.1097/PAS.0000000000000242. PMID: 24854113
Schild MH, Wong WW, Valdez R, Leis JF
J Surg Oncol 2014 Sep;110(3):341-4. Epub 2014 Apr 29 doi: 10.1002/jso.23624. [Epub ahead of print] PMID: 24777934
Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS
Cancer 2014 Jul 15;120(14):2122-9. Epub 2014 Apr 7 doi: 10.1002/cncr.28698. [Epub ahead of print] PMID: 24711253
Goel A, Fan W, Patel AA, Devabhaktuni M, Grossbard ML
Clin Lymphoma Myeloma Leuk 2014 Aug;14(4):261-70. Epub 2014 Feb 3 doi: 10.1016/j.clml.2014.01.006. [Epub ahead of print] PMID: 24650975
Bohn O, Maeda T, Filatov A, Lunardi A, Pandolfi PP, Teruya-Feldstein J
Int J Surg Pathol 2014 Feb;22(1):6-11. Epub 2013 Dec 10 doi: 10.1177/1066896913513833. [Epub ahead of print] PMID: 24326827Free PMC Article

Therapy

Schild MH, Wong WW, Valdez R, Leis JF
J Surg Oncol 2014 Sep;110(3):341-4. Epub 2014 Apr 29 doi: 10.1002/jso.23624. [Epub ahead of print] PMID: 24777934
Xing KH, Connors JM, Lai A, Al-Mansour M, Sehn LH, Villa D, Klasa R, Shenkier T, Gascoyne RD, Skinnider B, Savage KJ
Blood 2014 Jun 5;123(23):3567-73. Epub 2014 Apr 8 doi: 10.1182/blood-2013-12-541078. [Epub ahead of print] PMID: 24713929
Follows GA, Ardeshna KM, Barrington SF, Culligan DJ, Hoskin PJ, Linch D, Sadullah S, Williams MV, Wimperis JZ; British Committee for Standards in Haematology
Br J Haematol 2014 Jul;166(1):34-49. Epub 2014 Apr 9 doi: 10.1111/bjh.12878. [Epub ahead of print] PMID: 24712411
Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS
Cancer 2014 Jul 15;120(14):2122-9. Epub 2014 Apr 7 doi: 10.1002/cncr.28698. [Epub ahead of print] PMID: 24711253
Oki Y, Chuang H, Chasen B, Jessop A, Pan T, Fanale M, Dabaja B, Fowler N, Romaguera J, Fayad L, Hagemeister F, Rodriguez MA, Neelapu S, Samaniego F, Kwak L, Younes A
Br J Haematol 2014 Apr;165(1):112-6. Epub 2014 Jan 6 doi: 10.1111/bjh.12715. [Epub ahead of print] PMID: 24386943

Prognosis

Hollman-Hewgley D, Lazare M, Bordwell A, Zebadua E, Tripathi P, Ross AS, Fisher D, Adams A, Bouman D, O'Malley DP, Weiss LM
Am J Surg Pathol 2014 Sep;38(9):1193-202. doi: 10.1097/PAS.0000000000000242. PMID: 24854113
Xing KH, Connors JM, Lai A, Al-Mansour M, Sehn LH, Villa D, Klasa R, Shenkier T, Gascoyne RD, Skinnider B, Savage KJ
Blood 2014 Jun 5;123(23):3567-73. Epub 2014 Apr 8 doi: 10.1182/blood-2013-12-541078. [Epub ahead of print] PMID: 24713929
Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS
Cancer 2014 Jul 15;120(14):2122-9. Epub 2014 Apr 7 doi: 10.1002/cncr.28698. [Epub ahead of print] PMID: 24711253
Bohn O, Maeda T, Filatov A, Lunardi A, Pandolfi PP, Teruya-Feldstein J
Int J Surg Pathol 2014 Feb;22(1):6-11. Epub 2013 Dec 10 doi: 10.1177/1066896913513833. [Epub ahead of print] PMID: 24326827Free PMC Article
Xavier AC, Armeson KE, Hill EG, Costa LJ
Cancer 2013 Sep 15;119(18):3385-92. Epub 2013 Jun 24 doi: 10.1002/cncr.28194. [Epub ahead of print] PMID: 23797978Free PMC Article

Clinical prediction guides

Vogel MJ, Xie L, Guan H, Tooze RM, Maier T, Kostezka U, Maier HJ, Holzmann K, Chan FC, Steidl C, Reichel JB, Weitzer CD, Gehringer F, Kick AB, Cesarman E, Roshal M, Gascoyne RD, Möller P, Wirth T, Ushmorov A
Blood 2014 Nov 13;124(20):3118-29. Epub 2014 Sep 17 doi: 10.1182/blood-2014-07-590570. [Epub ahead of print] PMID: 25232062
Hollman-Hewgley D, Lazare M, Bordwell A, Zebadua E, Tripathi P, Ross AS, Fisher D, Adams A, Bouman D, O'Malley DP, Weiss LM
Am J Surg Pathol 2014 Sep;38(9):1193-202. doi: 10.1097/PAS.0000000000000242. PMID: 24854113
Venkataraman G, Mirza MK, Eichenauer DA, Diehl V
Br J Haematol 2014 May;165(3):287-99. Epub 2014 Feb 4 doi: 10.1111/bjh.12759. [Epub ahead of print] PMID: 24494650
Oki Y, Chuang H, Chasen B, Jessop A, Pan T, Fanale M, Dabaja B, Fowler N, Romaguera J, Fayad L, Hagemeister F, Rodriguez MA, Neelapu S, Samaniego F, Kwak L, Younes A
Br J Haematol 2014 Apr;165(1):112-6. Epub 2014 Jan 6 doi: 10.1111/bjh.12715. [Epub ahead of print] PMID: 24386943
Hartmann S, Jakobus C, Rengstl B, Döring C, Newrzela S, Brodt HR, Wolf T, Hansmann ML
Mod Pathol 2013 May;26(5):648-57. Epub 2013 Jan 11 doi: 10.1038/modpathol.2012.217. [Epub ahead of print] PMID: 23307058

Recent systematic reviews

Lee JH, Kim Y, Choi JW, Kim YS
Arch Med Res 2014 Jul;45(5):417-31. Epub 2014 Jun 14 doi: 10.1016/j.arcmed.2014.06.001. [Epub ahead of print] PMID: 24937173
Follows GA, Ardeshna KM, Barrington SF, Culligan DJ, Hoskin PJ, Linch D, Sadullah S, Williams MV, Wimperis JZ; British Committee for Standards in Haematology
Br J Haematol 2014 Jul;166(1):34-49. Epub 2014 Apr 9 doi: 10.1111/bjh.12878. [Epub ahead of print] PMID: 24712411
Venkataraman G, Mirza MK, Eichenauer DA, Diehl V
Br J Haematol 2014 May;165(3):287-99. Epub 2014 Feb 4 doi: 10.1111/bjh.12759. [Epub ahead of print] PMID: 24494650
Collins GP, Parker AN, Pocock C, Kayani I, Sureda A, Illidge T, Ardeshna K, Linch DC, Peggs KS; British Committee for Standards in Haematology; British Society of Blood and Marrow Transplantation
Br J Haematol 2014 Jan;164(1):39-52. Epub 2013 Oct 1 doi: 10.1111/bjh.12582. [Epub ahead of print] PMID: 24117159
Hoppe RT, Advani RH, Ai WZ, Ambinder RF, Aoun P, Bello CM, Bierman PJ, Blum KA, Chen R, Dabaja B, Duron Y, Forero A, Gordon LI, Hernandez-Ilizaliturri FJ, Hochberg EP, Maloney DG, Mansur D, Mauch PM, Metzger M, Moore JO, Morgan D, Moskowitz CH, Poppe M, Pro B, Winter JN, Yahalom J, Sundar H; National Comprehensive Cancer Network
J Natl Compr Canc Netw 2012 May;10(5):589-97. PMID: 22570290

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