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Acetylation

MedGen UID:
7840
Concept ID:
C0001038
Molecular Function
Synonyms: Acetylations
 

Definition

A chemical reaction in which a small molecule called an acetyl group is added to other molecules. Acetylation of proteins may affect how they act in the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGAcetylation

Recent clinical studies

Etiology

Ghanta S, Grossmann RE, Brenner C
Crit Rev Biochem Mol Biol 2013 Nov-Dec;48(6):561-74. Epub 2013 Sep 19 doi: 10.3109/10409238.2013.838204. [Epub ahead of print] PMID: 24050258Free PMC Article
Ge Y, Gong Z, Olson JR, Xu P, Buck MJ, Ren X
Toxicology 2013 Oct 4;312:30-5. Epub 2013 Jul 26 doi: 10.1016/j.tox.2013.07.011. [Epub ahead of print] PMID: 23891734
Lupisan S, Limkittikul K, Sosa N, Chanthavanich P, Bianco V, Baine Y, Van der Wielen M, Miller JM
Clin Vaccine Immunol 2013 Oct;20(10):1499-507. Epub 2013 Jul 24 doi: 10.1128/CVI.00162-13. [Epub ahead of print] PMID: 23885033Free PMC Article
Lodewick J, Sampaio C, Boxus M, Rinaldi AS, Coulonval K, Willems L, Roger PP, Bex F
Retrovirology 2013 Jul 23;10:75. doi: 10.1186/1742-4690-10-75. [Epub ahead of print] PMID: 23880157Free PMC Article
Elfert S, Weise A, Bruser K, Biniossek ML, Jägle S, Senghaas N, Hecht A
PLoS One 2013;8(4):e61867. Epub 2013 Apr 15 doi: 10.1371/journal.pone.0061867. PMID: 23613959Free PMC Article

Diagnosis

Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M
Nat Rev Mol Cell Biol 2014 Aug;15(8):536-50. doi: 10.1038/nrm3841. PMID: 25053359
Haaland I, Opsahl JA, Berven FS, Reikvam H, Fredly HK, Haugse R, Thiede B, McCormack E, Lain S, Bruserud O, Gjertsen BT
Mol Cancer 2014 May 21;13:116. doi: 10.1186/1476-4598-13-116. [Epub ahead of print] PMID: 24885082Free PMC Article
Ghanta S, Grossmann RE, Brenner C
Crit Rev Biochem Mol Biol 2013 Nov-Dec;48(6):561-74. Epub 2013 Sep 19 doi: 10.3109/10409238.2013.838204. [Epub ahead of print] PMID: 24050258Free PMC Article
Loureiro AI, Fernandes-Lopes C, Bonifácio MJ, Wright LC, Soares-da-Silva P
Drug Metab Dispos 2013 Dec;41(12):2081-6. Epub 2013 Sep 6 doi: 10.1124/dmd.113.053736. [Epub ahead of print] PMID: 24013186
Ge Y, Gong Z, Olson JR, Xu P, Buck MJ, Ren X
Toxicology 2013 Oct 4;312:30-5. Epub 2013 Jul 26 doi: 10.1016/j.tox.2013.07.011. [Epub ahead of print] PMID: 23891734

Therapy

Sethi G, Chatterjee S, Rajendran P, Li F, Shanmugam MK, Wong KF, Kumar AP, Senapati P, Behera AK, Hui KM, Basha J, Natesh N, Luk JM, Kundu TK
Mol Cancer 2014 Mar 21;13:66. doi: 10.1186/1476-4598-13-66. [Epub ahead of print] PMID: 24655440Free PMC Article
Pramanik KC, Fofaria NM, Gupta P, Srivastava SK
Mol Cancer Ther 2014 Mar;13(3):687-98. Epub 2014 Jan 13 doi: 10.1158/1535-7163.MCT-13-0863. [Epub ahead of print] PMID: 24419059Free PMC Article
Parbin S, Kar S, Shilpi A, Sengupta D, Deb M, Rath SK, Patra SK
J Histochem Cytochem 2014 Jan;62(1):11-33. Epub 2013 Sep 18 doi: 10.1369/0022155413506582. [Epub ahead of print] PMID: 24051359Free PMC Article
Lupisan S, Limkittikul K, Sosa N, Chanthavanich P, Bianco V, Baine Y, Van der Wielen M, Miller JM
Clin Vaccine Immunol 2013 Oct;20(10):1499-507. Epub 2013 Jul 24 doi: 10.1128/CVI.00162-13. [Epub ahead of print] PMID: 23885033Free PMC Article
Rajendran P, Kidane AI, Yu TW, Dashwood WM, Bisson WH, Löhr CV, Ho E, Williams DE, Dashwood RH
Epigenetics 2013 Jun;8(6):612-23. Epub 2013 Apr 26 doi: 10.4161/epi.24710. [Epub ahead of print] PMID: 23770684Free PMC Article

Prognosis

Law BM, Spain VA, Leinster VH, Chia R, Beilina A, Cho HJ, Taymans JM, Urban MK, Sancho RM, Blanca Ramírez M, Biskup S, Baekelandt V, Cai H, Cookson MR, Berwick DC, Harvey K
J Biol Chem 2014 Jan 10;289(2):895-908. Epub 2013 Nov 25 doi: 10.1074/jbc.M113.507913. [Epub ahead of print] PMID: 24275654Free PMC Article
Ghanta S, Grossmann RE, Brenner C
Crit Rev Biochem Mol Biol 2013 Nov-Dec;48(6):561-74. Epub 2013 Sep 19 doi: 10.3109/10409238.2013.838204. [Epub ahead of print] PMID: 24050258Free PMC Article
Zhang X, Qu X, Sun YB, Caruana G, Bertram JF, Nikolic-Paterson DJ, Li J
PLoS One 2013;8(6):e67471. Epub 2013 Jun 28 doi: 10.1371/journal.pone.0067471. PMID: 23840712Free PMC Article
Li J, Wang W, Liu C, Wang W, Li W, Shu Q, Chen ZJ, Sun K
J Clin Endocrinol Metab 2013 Jul;98(7):E1189-97. Epub 2013 May 28 doi: 10.1210/jc.2012-4291. [Epub ahead of print] PMID: 23714681
Di Cerbo V, Schneider R
Brief Funct Genomics 2013 May;12(3):231-43. Epub 2013 Jan 15 doi: 10.1093/bfgp/els065. [Epub ahead of print] PMID: 23325510

Clinical prediction guides

Legartová S, Kozubek S, Franek M, Zdráhal Z, Lochmanová G, Martinet N, Bártová E
Biochem Cell Biol 2014 Apr;92(2):85-93. Epub 2014 Jan 17 doi: 10.1139/bcb-2013-0082. [Epub ahead of print] PMID: 24697692
Zerzaihi O, Chriett S, Vidal H, Pirola L
Biochem Cell Biol 2014 Feb;92(1):61-7. Epub 2013 Nov 4 doi: 10.1139/bcb-2013-0071. [Epub ahead of print] PMID: 24471919
Zhao Y, Fang X, Wang Y, Zhang J, Jiang S, Liu Z, Ma Z, Xu L, Li E, Zhang K
Curr Pharm Des 2014;20(11):1866-73. PMID: 23888955
Montagnac G, Meas-Yedid V, Irondelle M, Castro-Castro A, Franco M, Shida T, Nachury MV, Benmerah A, Olivo-Marin JC, Chavrier P
Nature 2013 Oct 24;502(7472):567-70. Epub 2013 Oct 6 doi: 10.1038/nature12571. [Epub ahead of print] PMID: 24097348Free PMC Article
Loureiro AI, Fernandes-Lopes C, Bonifácio MJ, Wright LC, Soares-da-Silva P
Drug Metab Dispos 2013 Dec;41(12):2081-6. Epub 2013 Sep 6 doi: 10.1124/dmd.113.053736. [Epub ahead of print] PMID: 24013186

Recent systematic reviews

Rudenko A, Tsai LH
Neuropharmacology 2014 May;80:70-82. Epub 2014 Feb 1 doi: 10.1016/j.neuropharm.2014.01.043. [Epub ahead of print] PMID: 24495398
Wang Y, Zhang Q, Zhang M, Wang C
Mol Biol Rep 2014 Mar;41(3):1849-55. Epub 2014 Jan 19 doi: 10.1007/s11033-014-3034-8. [Epub ahead of print] PMID: 24442317
Pesch B, Gawrych K, Rabstein S, Weiss T, Casjens S, Rihs HP, Ding H, Angerer J, Illig T, Klopp N, Bueno-de-Mesquita B, Ros MM, Kaaks R, Chang-Claude J, Roswall N, Tjønneland A, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Dossus L, Boeing H, Weikert S, Trichopoulos D, Palli D, Sieri S, Tumino R, Panico S, Quirós JR, González C, Sánchez MJ, Dorronsoro M, Navarro C, Barricarte A, Ljungberg B, Johansson M, Ulmert D, Ehrnström R, Khaw KT, Wareham N, Key TJ, Ferrari P, Romieu I, Riboli E, Brüning T, Vineis P
Cancer Epidemiol Biomarkers Prev 2013 Nov;22(11):2055-65. Epub 2013 Oct 3 doi: 10.1158/1055-9965.EPI-13-0119-T. [Epub ahead of print] PMID: 24092628
Li Y, Alam HB
J Biomed Biotechnol 2011;2011:523481. Epub 2011 Feb 15 doi: 10.1155/2011/523481. PMID: 21403879Free PMC Article
Moore LE, Baris DR, Figueroa JD, Garcia-Closas M, Karagas MR, Schwenn MR, Johnson AT, Lubin JH, Hein DW, Dagnall CL, Colt JS, Kida M, Jones MA, Schned AR, Cherala SS, Chanock SJ, Cantor KP, Silverman DT, Rothman N
Carcinogenesis 2011 Feb;32(2):182-9. Epub 2010 Oct 29 doi: 10.1093/carcin/bgq223. [Epub ahead of print] PMID: 21037224Free PMC Article

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