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Results: 12

1.

Chromosomal Rearrangement

MedGen UID:
273151
Concept ID:
C1516520
Cell or Molecular Dysfunction
2.

Chromosomal structural abnormalities

Any change in the structure of one or more chromosomes. [from NCI]

MedGen UID:
271516
Concept ID:
C1515001
Cell or Molecular Dysfunction
3.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
4.

Genomic Instability

An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional. [from MeSH]

MedGen UID:
182518
Concept ID:
C0919532
Cell or Molecular Dysfunction
5.

Methyl Methanesulfonate

An alkylating agent in cancer therapy that may also act as a mutagen by interfering with and causing damage to DNA. [from MeSH]

MedGen UID:
7596
Concept ID:
C0025706
Pharmacologic Substance
6.

DNA damage

Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS. [from MeSH]

MedGen UID:
3880
Concept ID:
C0012860
Cell or Molecular Dysfunction
7.

Instability

MedGen UID:
731956
Concept ID:
C1444783
Finding
8.

Strand breaks

MedGen UID:
549441
Concept ID:
C0301647
Molecular Function
9.

Visual Suppression

MedGen UID:
526147
Concept ID:
C0221103
Pathologic Function
10.

Recruitment

MedGen UID:
78772
Concept ID:
C0271510
Disease or Syndrome
11.

Protein binding

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. [from MeSH]

MedGen UID:
18704
Concept ID:
C0033618
Molecular Function
12.

Alkyl sulfonate antineoplastic

MedGen UID:
580009
Concept ID:
C0360106
Pharmacologic Substance

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