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Items: 8

1.

Myocardial infarction

Each year over a million people in the U.S. have a heart attack. About half of them die. Many people have permanent heart damage or die because they don't get help immediately. It's important to know the symptoms of a heart attack and call 9-1-1 if someone is having them. Those symptoms include. -Chest discomfort - pressure, squeezing, or pain . -Shortness of breath . -Discomfort in the upper body - arms, shoulder, neck, back . -Nausea, vomiting, dizziness, lightheadedness, sweating . These symptoms can sometimes be different in women. What exactly is a heart attack? Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat - called an arrhythmia - that causes a severe decrease in the pumping function of the heart. A blockage that is not treated within a few hours causes the affected heart muscle to die. NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
10150
Concept ID:
C0027051
Disease or Syndrome
2.

Left bundle branch block

A conduction block of the left branch of the bundle of His. This manifests as a generalized disturbance of QRS morphology on EKG. [from HPO]

MedGen UID:
7286
Concept ID:
C0023211
Disease or Syndrome
3.

Bundle branch block

Block of conduction of electrical impulses along the Bundle of His or along one of its bundle branches. [from HPO]

MedGen UID:
2752
Concept ID:
C0006384
Disease or Syndrome; Finding
4.

Left bundle branch block

A conduction block of the left branch of the bundle of His. This manifests as a generalized disturbance of QRS morphology on EKG. [from HPO]

MedGen UID:
506610
Concept ID:
CN167441
Finding
5.

Bundle branch block

Block of conduction of electrical impulses along the Bundle of His or along one of its bundle branches. [from HPO]

MedGen UID:
506607
Concept ID:
CN167438
Finding
6.

Myocardial infarction

Necrosis of the myocardium caused by an obstruction of the blood supply to the heart and often associated with chest pain, shortness of breath, palpitations, and anxiety as well as characteristic EKG findings and elevation of serum markers including creatine kinase-MB fraction and troponin. [from HPO]

MedGen UID:
504896
Concept ID:
CN001509
Finding
7.

Progressive familial heart block type 1A

Progressive familial heart block type I (PFHBI, PFHB1) is an autosomal dominant cardiac bundle branch disorder that may progress to complete heart block (Brink and Torrington, 1977; van der Merwe et al., 1986; van der Merwe et al., 1988). It is defined on electrocardiogram by evidence of bundle branch disease, i.e., right bundle branch block, left anterior or posterior hemiblock, or complete heart block, with broad QRS complexes. Progression has been shown from a normal electrocardiogram to right bundle branch block and from the latter to complete heart block. These electrocardiographic features differentiate PFHB type I from progressive familial heart block type II (PFHBII, PFHB2; 140400), in which the onset of complete heart block is associated with narrow complexes. Electrocardiographically the changes represent, respectively, bundle branch disease (PFHB1) and atrioventricular nodal disease with an atrioventricular block and an idionodal escape rhythm (PFHB2). PFHBI is manifested symptomatically when complete heart block supervenes, either with dyspnea, syncopal episodes, or sudden death. Treatment, which is best managed by regular electrocardiographic follow-up, is by the timely implantation of a pacemaker (Brink et al., 1995). Genetic Heterogeneity of Progressive Familial Heart Block Type I Progressive familial heart block type IB (PFHB1B; 604559) is caused by mutation in the TRPM4 gene (606936) on chromosome 19q13.32. [from OMIM]

MedGen UID:
406301
Concept ID:
C1879286
Disease or Syndrome
8.

ST segment elevation

An electrocardiographic anomaly in which the ST segment is observed to be located superior to the isoelectric line. [from HPO]

MedGen UID:
99256
Concept ID:
C0520886
Finding
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