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Results: 1 to 20 of 37

1.

Non-nucleoside Reverse Transcriptase Inhibitor

A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication. [from NCI]

MedGen UID:
760802
Concept ID:
C3537104
Pharmacologic Substance
2.

Nucleoside Reverse Transcriptase Inhibitor

A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases. [from NCI]

MedGen UID:
760801
Concept ID:
C3537103
Pharmacologic Substance
3.

Non-Nucleoside Reverse Transcriptase Inhibitors [MoA]

MedGen UID:
473404
Concept ID:
C1373120
Molecular Function
4.

Nucleoside Reverse Transcriptase Inhibitors [MoA]

MedGen UID:
473403
Concept ID:
C1373111
Molecular Function
5.

Reverse Transcriptase Inhibitors

Any substance that inhibits the activity of viral reverse transcriptase, an RNA-dependent DNA polymerase that transcribes viral RNA into DNA during virus replication. [from NCI]

MedGen UID:
79467
Concept ID:
C0282519
Pharmacologic Substance
6.

efavirenz

A drug used with other drugs to treat infection with the human immunodeficiency virus (HIV). It blocks HIV from making copies of itself. It is a type of non-nucleoside reverse transcriptase inhibitor and a type of antiviral agent. [from NCI]

MedGen UID:
194090
Concept ID:
C0674428
Pharmacologic Substance
7.

Nevirapine

A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV infection and AIDS. [from MeSH]

MedGen UID:
51679
Concept ID:
C0132326
Pharmacologic Substance
8.

Withdrawn

MedGen UID:
602872
Concept ID:
C0424092
Finding
9.

Body mass index

Body mass index (BMI), which reflects the amount of fat, lean mass, and body build, is a heterogeneous trait influenced by both genetic and environmental factors. Several studies have estimated the heritability of body mass index to be 40 to 55% (Bouchard et al., 1998; Rice et al., 1999). [from OMIM]

MedGen UID:
449535
Concept ID:
C2240399
Finding
10.

Mass of body structure

In medicine, a lump in the body. It may be caused by the abnormal growth of cells, a cyst, hormonal changes, or an immune reaction. A mass may be benign (not cancer) or malignant (cancer). [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
11.

AIDS

A disease caused by human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system. [from NCI]

MedGen UID:
99
Concept ID:
C0001175
Disease or Syndrome
12.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
13.

Antimicrobial substance

Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). [from NCI]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
14.

BI-RG-587

MedGen UID:
152715
Concept ID:
C0733416
Pharmacologic Substance
15.

Viramune

MedGen UID:
152574
Concept ID:
C0728726
Pharmacologic Substance
16.

Nucleic Acid Synthesis Inhibitors

Compounds that inhibit cell production of DNA or RNA. [from MeSH]

MedGen UID:
138218
Concept ID:
C0376568
Pharmacologic Substance
17.

Anti-Retroviral Agents

Agents used to treat RETROVIRIDAE INFECTIONS. [from MeSH]

MedGen UID:
109361
Concept ID:
C0599685
Pharmacologic Substance
18.

Viral disease

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers. . Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick. Viral infections are hard to treat because viruses live inside your body's cells. They are protected from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
19.

Sexually Transmitted Diseases, Viral

Viral diseases which are transmitted or propagated by sexual conduct. [from MeSH]

MedGen UID:
48646
Concept ID:
C0036918
Disease or Syndrome
20.

Disease due to Retroviridae

Virus diseases caused by the RETROVIRIDAE. [from MeSH]

MedGen UID:
48440
Concept ID:
C0035369
Disease or Syndrome

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