Format

Send to:

Choose Destination

MedGen for PubMed (Select 17936445)

Tetanus

MedGen UID:
21489
Concept ID:
C0039614
Disease or Syndrome
Synonyms: Infection due to Clostridium tetani
SNOMED CT: Tetanus (76902006); Infection due to Clostridium tetani (276202003)
 
Orphanet: ORPHA3299

Definition

Tetanus is a serious illness caused by Clostridium bacteria. The bacteria live in soil, saliva, dust, and manure. The bacteria can enter the body through a deep cut, like those you might get from stepping on a nail, or through a burn. The infection causes painful tightening of the muscles, usually all over the body. It can lead to locking of the jaw. This makes it impossible to open your mouth or swallow. Tetanus is a medical emergency. You need to get treatment in a hospital. A vaccine can prevent tetanus. It is given as a part of routine childhood immunization. Adults should get a tetanus shot, or booster, every 10 years. If you get a bad cut or burn, see your doctor - you may need a booster. Immediate and proper wound care can prevent tetanus infection.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGTetanus
Follow this link to review classifications for Tetanus in Orphanet.

Recent clinical studies

Etiology

Khan EA, Khan R, Iqbal MT, Hasan Q, Farrukh S, Rana MS, Khan WM
J Ayub Med Coll Abbottabad 2015 Jan-Mar;27(1):220-2. PMID: 26182781
Orsi GB, Modini C, Principe MA, Di Muzio M, Moriconi A, Amato MG, Calderale SM
Ann Ig 2015 Mar-Apr;27(2):467-74. PMID: 26051145
Thwaites CL, Beeching NJ, Newton CR
Lancet 2015 Jan 24;385(9965):362-70. Epub 2014 Aug 19 doi: 10.1016/S0140-6736(14)60236-1. [Epub ahead of print] PMID: 25149223
Boles EE, Chiuzan C, Ragucci D, Hudspeth MP
Pediatr Transplant 2014 Dec;18(8):882-8. Epub 2014 Sep 22 doi: 10.1111/petr.12361. [Epub ahead of print] PMID: 25243374
Rohde KA, Cunningham KC, Henriquez KM, Nielsen AR, Worzella SL, Hayney MS
Transpl Infect Dis 2014 Dec;16(6):871-7. Epub 2014 Sep 2 doi: 10.1111/tid.12288. [Epub ahead of print] PMID: 25180932

Diagnosis

Yen C, Murray E, Zipprich J, Winter K, Harriman K; Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2015 Mar 13;64(9):243-6. PMID: 25763876
Thwaites CL, Beeching NJ, Newton CR
Lancet 2015 Jan 24;385(9965):362-70. Epub 2014 Aug 19 doi: 10.1016/S0140-6736(14)60236-1. [Epub ahead of print] PMID: 25149223
N'Diaye DS, Schwarzinger M, Obach D, Poissy J, Matheron S, Casalino E, Yazdanpanah Y
BMC Infect Dis 2014 Nov 19;14:603. doi: 10.1186/s12879-014-0603-3. [Epub ahead of print] PMID: 25407690Free PMC Article
McCabe J, La Varis T, Mason D
N Z Med J 2014 Aug 15;127(1400):98-100. PMID: 25145370
Sule SS, Nkem-Uchendu C, Onajole AT, Ogunowo BE
Niger Postgrad Med J 2014 Jun;21(2):107-14. PMID: 25126863

Therapy

Orsi GB, Modini C, Principe MA, Di Muzio M, Moriconi A, Amato MG, Calderale SM
Ann Ig 2015 Mar-Apr;27(2):467-74. PMID: 26051145
Yen C, Murray E, Zipprich J, Winter K, Harriman K; Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2015 Mar 13;64(9):243-6. PMID: 25763876
Demir NA, Sumer S, Ural O, Ozturk S, Celik JB
Trop Doct 2015 Jan;45(1):46-8. Epub 2014 Sep 18 doi: 10.1177/0049475514550063. [Epub ahead of print] PMID: 25234426
Thwaites CL, Beeching NJ, Newton CR
Lancet 2015 Jan 24;385(9965):362-70. Epub 2014 Aug 19 doi: 10.1016/S0140-6736(14)60236-1. [Epub ahead of print] PMID: 25149223
Rohde KA, Cunningham KC, Henriquez KM, Nielsen AR, Worzella SL, Hayney MS
Transpl Infect Dis 2014 Dec;16(6):871-7. Epub 2014 Sep 2 doi: 10.1111/tid.12288. [Epub ahead of print] PMID: 25180932

Prognosis

Khan EA, Khan R, Iqbal MT, Hasan Q, Farrukh S, Rana MS, Khan WM
J Ayub Med Coll Abbottabad 2015 Jan-Mar;27(1):220-2. PMID: 26182781
Thwaites CL, Beeching NJ, Newton CR
Lancet 2015 Jan 24;385(9965):362-70. Epub 2014 Aug 19 doi: 10.1016/S0140-6736(14)60236-1. [Epub ahead of print] PMID: 25149223
Boles EE, Chiuzan C, Ragucci D, Hudspeth MP
Pediatr Transplant 2014 Dec;18(8):882-8. Epub 2014 Sep 22 doi: 10.1111/petr.12361. [Epub ahead of print] PMID: 25243374
Zieliński A
Przegl Epidemiol 2014;68(2):271-3, 373-4. PMID: 25135513
Narang M, Khurana A, Gomber S, Choudhary N
J Infect Public Health 2014 Mar-Apr;7(2):121-4. Epub 2013 Nov 24 doi: 10.1016/j.jiph.2013.07.006. [Epub ahead of print] PMID: 24284024

Clinical prediction guides

Khan EA, Khan R, Iqbal MT, Hasan Q, Farrukh S, Rana MS, Khan WM
J Ayub Med Coll Abbottabad 2015 Jan-Mar;27(1):220-2. PMID: 26182781
Boles EE, Chiuzan C, Ragucci D, Hudspeth MP
Pediatr Transplant 2014 Dec;18(8):882-8. Epub 2014 Sep 22 doi: 10.1111/petr.12361. [Epub ahead of print] PMID: 25243374
Orimadegun AE, Adepoju AA, Akinyinka OO
Ital J Pediatr 2014 Mar 17;40(1):29. doi: 10.1186/1824-7288-40-29. [Epub ahead of print] PMID: 24636576Free PMC Article
Chopra A, Cevc G
Eur J Pharm Sci 2014 Jun 2;56:55-64. Epub 2014 Feb 18 doi: 10.1016/j.ejps.2014.01.006. [Epub ahead of print] PMID: 24560940
Filia A, Bella A, von Hunolstein C, Pinto A, Alfarone G, Declich S, Rota MC
Vaccine 2014 Feb 3;32(6):639-44. Epub 2013 Dec 25 doi: 10.1016/j.vaccine.2013.12.012. [Epub ahead of print] PMID: 24370712

Recent systematic reviews

Hemilä H, Koivula T
Cochrane Database Syst Rev 2013 Nov 13;11:CD006665. doi: 10.1002/14651858.CD006665.pub3. PMID: 24226506
Lambo JA, Anokye EA
Int J Infect Dis 2013 Dec;17(12):e1100-10. Epub 2013 Oct 19 doi: 10.1016/j.ijid.2013.05.016. [Epub ahead of print] PMID: 24145010
Demicheli V, Barale A, Rivetti A
Cochrane Database Syst Rev 2013 May 31;5:CD002959. doi: 10.1002/14651858.CD002959.pub3. PMID: 23728640
Khan AA, Zahidie A, Rabbani F
BMC Public Health 2013 Apr 9;13:322. doi: 10.1186/1471-2458-13-322. [Epub ahead of print] PMID: 23570611Free PMC Article
Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2012 Jun 29;61(25):468-70. PMID: 22739778

Supplemental Content

Table of contents

    Outreach and support

    PubMed Health

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...