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Results: 1 to 20 of 32

1.

Malignant melanoma

Melanoma is the most serious type of skin cancer. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or ugly looking.. Thinking of ABCDE can help you remember what to watch for:: - Asymmetry - the shape of one half does not match the other. - Border - the edges are ragged, blurred or irregular. - Color - the color is uneven and may include shades of black, brown and tan. - Diameter - there is a change in size, usually an increase. -Evolving - the mole has changed over the past few weeks or months. Surgery is the first treatment of all stages of melanoma. Other treatments include chemotherapy and radiation, biologic, and targeted therapies. Biologic therapy boosts your body's own ability to fight cancer. Targeted therapy uses substances that attack cancer cells without harming normal cells. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
9944
Concept ID:
C0025202
Neoplastic Process
2.

Diagnosis

The process of identifying a disease, such as cancer, from its signs and symptoms. [from NCI]

MedGen UID:
8354
Concept ID:
C0011900
Finding
3.

Melanoma

The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea). [from HPO]

MedGen UID:
505377
Concept ID:
CN002586
Finding
4.

Lesion

An area of abnormal tissue. A lesion may be benign (not cancer) or malignant (cancer). [from NCI]

MedGen UID:
65128
Concept ID:
C0221198
Finding
5.

Probe brand of methazole herbicide

brand name of methazole herbicide [from CHV]

MedGen UID:
152600
Concept ID:
C0728863
Pharmacologic Substance
6.

Methylation

A chemical reaction in which a small molecule called a methyl group is added to other molecules. Methylation of proteins or nucleic acids may affect how they act in the body. [from NCI]

MedGen UID:
44400
Concept ID:
C0025723
Molecular Function
7.

Error occurred: cannot get document summary

ID:
775793

8.

Nevus

A nevus is a type of hamartoma that is a circumscribed stable malformation of the skin. [from HPO]

MedGen UID:
425158
Concept ID:
CN003400
Finding
9.

Cyclin-Dependent Kinase Inhibitor Agents

Agents that inhibit Cyclin-dependent Kinase, enzymes that regulate cell cycle progression, and may promote differentiation, induce apoptosis, and inhibit angiogenesis. [from NCI]

MedGen UID:
267474
Concept ID:
C1511576
Pharmacologic Substance
10.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
11.

Cancer, Embryonal

MedGen UID:
199639
Concept ID:
C0751364
Neoplastic Process
12.

Neuroendocrine neoplasm

Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. [from MeSH]

MedGen UID:
64652
Concept ID:
C0206754
Neoplastic Process
13.

Nevi and Melanomas

A collective term for the various types of nevi and melanomas. [from MeSH]

MedGen UID:
61679
Concept ID:
C0206769
Neoplastic Process
14.

Spitz Nevus

A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumor presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in color from pink-tan to purplish red, often with surface telangiectasia. (Dorland, 27th ed) [from MeSH]

MedGen UID:
61671
Concept ID:
C0206739
Neoplastic Process
15.

Spindle Cell Nevus

A nevus characterized by the presence of spindle-shaped melanocytes. [from NCI]

MedGen UID:
60220
Concept ID:
C0206738
Neoplastic Process
16.

Neuroectodermal neoplasm

A tumor of the central or peripheral nervous system. [from NCI]

MedGen UID:
60072
Concept ID:
C0206093
Neoplastic Process
17.

Skin and Connective Tissue Diseases

A collective term for diseases of the skin and its appendages and of connective tissue. [from MeSH]

MedGen UID:
59786
Concept ID:
C0175166
Disease or Syndrome
18.

Nevus

Moles are growths on the skin. They happen when pigment cells in the skin, called melanocytes, grow in clusters. Moles are very common. Most people have between 10 and 40 moles. A person may develop new moles from time to time, usually until about age 40. In older people, they tend to fade away. Moles are usually pink, tan or brown. They can be flat or raised. They are usually round or oval and no larger than a pencil eraser. About one out of every ten people has at least one unusual (or atypical) mole that looks different from an ordinary mole. They are called dysplastic nevi. They may be more likely than ordinary moles to develop into melanoma, a type of skin cancer. You should have a health care professional check your moles if they look unusual, grow larger, change in color or outline, or in any other way. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
45074
Concept ID:
C0027960
Neoplastic Process
19.

Embryonal Neoplasm

new abnormal embryonic tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease. [from CRISP]

MedGen UID:
45034
Concept ID:
C0027654
Neoplastic Process
20.

Disorder of skin

Did you know that your skin is the largest organ of your body? It is, in terms of both weight, between 6 and 9 pounds, and surface area, about 2 square yards. Your skin separates the inside of your body from the outside world. It: -Protects you from bacteria and viruses that can cause infections. -Helps you sense the outside world, such as whether it is hot or cold, wet or dry. -Regulates your body temperature . Conditions that irritate, clog or inflame your skin can cause symptoms such as redness, swelling, burning and itching. Allergies, irritants, your genetic makeup and certain diseases and immune system problems can cause dermatitis, hives and other skin conditions. Many skin problems, such as acne, also affect your appearance.  [from MedlinePlus]

MedGen UID:
20777
Concept ID:
C0037274
Disease or Syndrome

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