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Results: 1 to 20 of 42

1.

Erythromelalgia

A peripheral arterial disease that is characterized by the triad of ERYTHEMA, burning PAIN, and increased SKIN TEMPERATURE of the extremities (or red, painful extremities). Erythromelalgia may be classified as primary or idiopathic, familial or non-familial. Secondary erythromelalgia is associated with other diseases, the most common being MYELOPROLIFERATIVE DISORDERS. [from MeSH]

MedGen UID:
8687
Concept ID:
C0014804
Disease or Syndrome
2.

Lidocaine

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE. [from MeSH]

MedGen UID:
6090
Concept ID:
C0023660
Pharmacologic Substance
3.

Primary erythromelalgia

SCN9A-related inherited erythromelalgia (SCN9A-related IEM) is characterized by recurrent attacks of bilateral and symmetric intense pain, redness, warmth, and swelling involving the feet and, less frequently, the hands. SCN9A-related IEM is not associated with an organic disease. Manifestations may vary within a family. Onset is usually in childhood or adolescence but has been recognized in infants and adults. At onset, episodes are triggered by warmth; other precipitating factors include: exercise, tight shoes, wearing socks, alcohol, spicy foods, and other vasodilating agents. In advanced disease, symptoms may occur many times a day or become constant. Some individuals have allodynia (pain evoked by a normally innocuous stimulus) and hyperalgesia (increased sensitivity to a painful stimulus). Episodes may be disabling, interfere with sleep, and severely limit normal activities such as walking, participation in sports, wearing socks and shoes, and attending school or going to work. [from GeneReviews]

MedGen UID:
8688
Concept ID:
C0014805
Disease or Syndrome
4.

Excitability

MedGen UID:
536361
Concept ID:
C0235169
Sign or Symptom
5.

Peripheral neuropathy

Peripheral neuropathy is a general term for any disorder of the `peripheral nervous system` (FMA:9903). The main clinical features used to classify peripheral neuropathy are distribution, type (mainly demyelinating versus mainly axonal), duration, and course. [from HPO]

MedGen UID:
506330
Concept ID:
CN008687
Finding
6.

Neuropathy

nervous system disorder [from CHV]

MedGen UID:
141046
Concept ID:
C0442874
Disease or Syndrome
7.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
8.

Inherited neuropathies

A hereditary disorder that affects the sensory and/or motor nerves or the autonomic nerves. [from NCI]

MedGen UID:
108622
Concept ID:
C0598589
Disease or Syndrome
9.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
10.

Pain

Unpleasant sensory and emotional experience associated with actual or potential tissue damage. [from OMS]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
11.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
12.

Topical anesthetic

Anesthetic applied on a specific site of body. [from MeSH]

MedGen UID:
452114
Concept ID:
C0040464
Pharmacologic Substance
13.

Membrane Transport Modulators

Agents that affect ION PUMPS; ION CHANNELS; ABC TRANSPORTERS; and other MEMBRANE TRANSPORT PROTEINS. [from MeSH]

MedGen UID:
288786
Concept ID:
C1563710
Pharmacologic Substance
14.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
15.

Xylesthesin

MedGen UID:
196193
Concept ID:
C0702204
Pharmacologic Substance
16.

Xylocaine

MedGen UID:
195824
Concept ID:
C0699094
Pharmacologic Substance
17.

Octocaine

MedGen UID:
181800
Concept ID:
C0949345
Pharmacologic Substance
18.

Sodium Channel Blockers

A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity. [from MeSH]

MedGen UID:
164031
Concept ID:
C0872271
Pharmacologic Substance
19.

Xylocitin

MedGen UID:
148831
Concept ID:
C0702203
Pharmacologic Substance
20.

Dalcaine

MedGen UID:
116575
Concept ID:
C0242375
Pharmacologic Substance

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