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Results: 7

1.

Thyroid carcinoma

Your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. It makes hormones that help the body work normally. There are several types of cancer of the thyroid gland. You are at greater risk if you: -Are between ages 25 and 65. -Are a woman. -Are Asian. -Have a family member who has had thyroid disease. -Have had radiation treatments to your head or neck. You should see a doctor if you have a lump or swelling in your neck. Doctors use a physical exam, blood tests, imaging tests, and a biopsy to diagnose thyroid cancer. Treatment depends on the type of cancer you have and how far the cancer has spread. Many patients receive a combination of treatments. They may include surgery, radioactive iodine, hormone treatment, radiation therapy, chemotherapy, or targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
107811
Concept ID:
C0549473
Neoplastic Process
2.

Iodine

A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. [from MeSH]

MedGen UID:
5877
Concept ID:
C0021968
Pharmacologic Substance
3.

Carcinoma

type of cancer [from CHV]

MedGen UID:
2867
Concept ID:
C0007097
Neoplastic Process
4.

Papillary thyroid carcinoma

The presence of a `papillary adenocarcinoma` (MPATH:295) of the `thyroid gland` (FMA:9603). [from HPO]

MedGen UID:
505394
Concept ID:
CN002618
Finding
5.

Thyroid carcinoma

The presence of a `carcinoma` (MPATH:549) of the `thyroid gland` (FMA:9603). [from HPO]

MedGen UID:
505391
Concept ID:
CN002613
Finding
6.

Radioactive Iodine

A radioactive form of iodine, often used for imaging tests or to treat an overactive thyroid, thyroid cancer, and certain other cancers. For imaging tests, the patient takes a small dose of radioactive iodine that collects in thyroid cells and certain kinds of tumors and can be detected by a scanner. To treat thyroid cancer, the patient takes a large dose of radioactive iodine, which kills thyroid cells. Radioactive iodine is also used in internal radiation therapy for prostate cancer, intraocular (eye) melanoma, and carcinoid tumors. Radioactive iodine is given by mouth as a liquid or in capsules, by infusion, or sealed in seeds, which are placed in or near the tumor to kill cancer cells. [from NCI]

MedGen UID:
254819
Concept ID:
C1441129
Pharmacologic Substance
7.

Papillary thyroid carcinoma

Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin and accounts for more than 95% of all thyroid cancer cases (summary by Vriens et al., 2009). The remaining cancers originate from parafollicular cells (medullary thyroid cancer, MTC; 155240). NMTC is classified into 4 groups: papillary, follicular (188470), Hurthle cell (607464), and anaplastic. Approximately 5% of NMTC is hereditary, occurring as a component of a familial cancer syndrome (e.g., familial adenomatous polyposis 175100, Carney complex 160980) or as a primary feature (familial NMTC or FNMTC). Papillary thyroid cancer (PTC) is the most common histologic subtype of FNMTC, accounting for approximately 85% of cases. PTC is characterized by distinctive nuclear alterations including pseudoinclusions, grooves, and chromatin clearing (summary by Bonora et al., 2010). PTCs smaller than 1 cm are referred to as papillary microcarcinomas. These tumors have been identified in up to 35% of individuals at autopsy, suggesting that they may be extremely common although rarely clinically relevant. PTC can also be multifocal but is typically slow-growing with a tendency to spread to lymph nodes and usually has an excellent prognosis. [from OMIM]

MedGen UID:
66773
Concept ID:
C0238463
Neoplastic Process

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