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Results: 5

1.

mRNA Decay

MedGen UID:
226188
Concept ID:
C1257758
Molecular Function
2.

Instability

MedGen UID:
731956
Concept ID:
C1444783
Finding
3.

Upshaw-Schulman syndrome

The classic pentad of TTP includes hemolytic anemia with fragmentation of erythrocytes, thrombocytopenia, diffuse and nonfocal neurologic findings, decreased renal function, and fever. Congenital TTP, also known as Schulman-Upshaw syndrome, is characterized by neonatal onset, response to fresh plasma infusion, and frequent relapses (Savasan et al., 2003; Kokame et al., 2002). Acquired TTP, which is usually sporadic, usually occurs in adults and is caused by an IgG inhibitor against the von Willebrand factor-cleaving protease. [from OMIM]

MedGen UID:
224783
Concept ID:
C1268935
Disease or Syndrome
4.

Ro-23-6019

MedGen UID:
214655
Concept ID:
C0919268
Pharmacologic Substance
5.

Protein binding

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. [from MeSH]

MedGen UID:
18704
Concept ID:
C0033618
Molecular Function

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