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Results: 9

1.

Hypocalcemia

Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed) [from MeSH]

MedGen UID:
5705
Concept ID:
C0020598
Pathologic Function
2.

Autosomal dominant hypocalcemia

MedGen UID:
832906
Concept ID:
CN228164
Disease or Syndrome
3.

edetate

MedGen UID:
758755
Concept ID:
C3495351
Pharmacologic Substance
4.

Hypocalcemia

An abnormally decreased calcium concentration in the blood. [from HPO]

MedGen UID:
505397
Concept ID:
CN002624
Finding
5.

Edetic Acid, Disodium Salt

The disodium salt form of edetate, a heavy metal chelating agent with anti-hypercalcemic and anti-arrhythmic properties. Edetate, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes which are readily excreted by the kidneys, thereby can be used to lower serum calcium concentrations. In addition, this agent exerts a negative inotropic effect on the heart through a transiently induced hypocalcemic state, thereby antagonizing the inotropic and chronotropic effects of digitalis glycosides on the ventricles of the heart. Upon ocular administration, edetate exerts its ophthalmic effect by chelating calcium to form soluble complexes, thereby removing corneal calcium deposits. [from NCI]

MedGen UID:
8437
Concept ID:
C0012695
Pharmacologic Substance
6.

Succicaptal

MedGen UID:
327703
Concept ID:
C1564182
Pharmacologic Substance
7.

Chemet

MedGen UID:
152439
Concept ID:
C0719256
Pharmacologic Substance
8.

Ro-1-7977

MedGen UID:
149079
Concept ID:
C0729192
Pharmacologic Substance
9.

Succimer

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them. [from MeSH]

MedGen UID:
4314
Concept ID:
C0012384
Pharmacologic Substance

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