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Results: 7

1.

olanzapine

a drug used to treat schizophrenia [from CHV]

MedGen UID:
104292
Concept ID:
C0171023
Pharmacologic Substance
2.

ziprasidone

A benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone also inhibits the synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors. [from NCI]

MedGen UID:
93402
Concept ID:
C0380393
Pharmacologic Substance
3.

Schizophrenia

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease (104300). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, van Os and Kapur (2009) noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome. [from OMIM]

MedGen UID:
48574
Concept ID:
C0036341
Mental or Behavioral Dysfunction
4.

Symptoms of depression

MedGen UID:
39170
Concept ID:
C0086132
Sign or Symptom
5.

Schizoaffective Disorder

Mental disorder characterized by the presence of both affective disorder and schizophrenia-like symptoms. [from PSY]

MedGen UID:
11334
Concept ID:
C0036337
Mental or Behavioral Dysfunction
6.

Schizophrenia

A mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3-0.7%. [from HPO]

MedGen UID:
506532
Concept ID:
CN117643
Finding
7.

Olanzapine

MedGen UID:
450006
Concept ID:
CN077531
Pharmacologic Substance

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