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fidarestat

MedGen UID:
172751
Concept ID:
C0905478
Pharmacologic Substance
Synonyms: (2S,4S)-6-fluoro-2',5'-dioxospiro(chroman-4,4'-imidazolidine)-2-carboxamide; Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 6-fluoro-2,3-dihydro-2',5'-dioxo-, (2S-cis)-
 

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGfidarestat

Recent clinical studies

Etiology

Saxena A, Shoeb M, Tammali R, Ramana KV, Srivastava SK
Cancer Lett 2014 Dec 1;355(1):141-7. Epub 2014 Sep 10 doi: 10.1016/j.canlet.2014.09.006. [Epub ahead of print] PMID: 25218594
Fournier B, Bendeif el-E, Guillot B, Podjarny A, Lecomte C, Jelsch C
J Am Chem Soc 2009 Aug 12;131(31):10929-41. doi: 10.1021/ja8095015. PMID: 19594152
Petrova T, Steuber H, Hazemann I, Cousido-Siah A, Mitschler A, Chung R, Oka M, Klebe G, El-Kabbani O, Joachimiak A, Podjarny A
J Med Chem 2005 Sep 8;48(18):5659-65. doi: 10.1021/jm050424+. PMID: 16134934
Asano T, Saito Y, Kawakami M, Yamada N; Fidarestat Clinical Pharmacology Study Group
J Diabetes Complications 2002 Mar-Apr;16(2):133-8. PMID: 12039395
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. PMID: 11574441

Diagnosis

Srivastava SK, Yadav UC, Reddy AB, Saxena A, Tammali R, Shoeb M, Ansari NH, Bhatnagar A, Petrash MJ, Srivastava S, Ramana KV
Chem Biol Interact 2011 May 30;191(1-3):330-8. Epub 2011 Feb 24 doi: 10.1016/j.cbi.2011.02.023. [Epub ahead of print] PMID: 21354119Free PMC Article

Therapy

Yadav UC, Mishra R, Aguilera-Aguirre L, Sur S, Bolodgh I, Ramana KV, Srivatsava SK
Inflamm Allergy Drug Targets 2013 Jun;12(3):178-86. PMID: 23360251
Yadav UC, Srivastava SK, Ramana KV
J Diabetes Complications 2012 Sep-Oct;26(5):369-77. Epub 2012 May 31 doi: 10.1016/j.jdiacomp.2012.04.017. [Epub ahead of print] PMID: 22658411Free PMC Article
Asano T, Saito Y, Kawakami M, Yamada N, Sekino H, Hasegawa S; Fidarestat Clinical Pharmacology Study Group
J Diabetes Complications 2004 Nov-Dec;18(6):336-42. doi: 10.1016/j.diacomp.2004.04.003. PMID: 15531183
Asano T, Saito Y, Kawakami M, Yamada N; Fidarestat Clinical Pharmacology Study Group
J Diabetes Complications 2002 Mar-Apr;16(2):133-8. PMID: 12039395
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. PMID: 11574441

Prognosis

Darmanin C, Chevreux G, Potier N, Van Dorsselaer A, Hazemann I, Podjarny A, El-Kabbani O
Bioorg Med Chem 2004 Jul 15;12(14):3797-806. doi: 10.1016/j.bmc.2004.05.014. PMID: 15210146
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. PMID: 11574441

Clinical prediction guides

Tammali R, Reddy AB, Saxena A, Rychahou PG, Evers BM, Qiu S, Awasthi S, Ramana KV, Srivastava SK
Carcinogenesis 2011 Aug;32(8):1259-67. Epub 2011 Jun 3 doi: 10.1093/carcin/bgr102. [Epub ahead of print] PMID: 21642355Free PMC Article
Asano T, Saito Y, Kawakami M, Yamada N, Sekino H, Hasegawa S; Fidarestat Clinical Pharmacology Study Group
J Diabetes Complications 2004 Nov-Dec;18(6):336-42. doi: 10.1016/j.diacomp.2004.04.003. PMID: 15531183
El-Kabbani O, Darmanin C, Oka M, Schulze-Briese C, Tomizaki T, Hazemann I, Mitschler A, Podjarny A
J Med Chem 2004 Aug 26;47(18):4530-7. doi: 10.1021/jm0497794. PMID: 15317464
Podjarny A, Cachau RE, Schneider T, Van Zandt M, Joachimiak A
Cell Mol Life Sci 2004 Apr;61(7-8):763-73. doi: 10.1007/s00018-003-3404-1. PMID: 15095001
Oka M, Matsumoto Y, Sugiyama S, Tsuruta N, Matsushima M
J Med Chem 2000 Jun 15;43(12):2479-83. PMID: 10882376

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