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Recombinant Interleukin-6

MedGen UID:
282851
Concept ID:
C1527132
Pharmacologic Substance
Synonyms: B Cell Differentiation Factor 2; B-Cell Stimulatory Factor-2; Hepatocyte Stimulating Factor; HPGF; HSF; Hybridoma Growth Factor; IFN Beta 2; IL-6; Interleukin-6; Myeloid Differentiation Inducing Protein; Plasmacytoma Growth Factor
 

Definition

Interleukin-6. A type of biological response modifier (a substance that can improve the body's natural response to infection and disease). These substances are normally produced by the body, but they can also be made in the laboratory. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGRecombinant Interleukin-6

Recent clinical studies

Etiology

Olencki T, Finke J, Tubbs R, Elson P, McLain D, Herzog P, Budd GT, Gunn H, Bukowski RM
J Immunother 2000 Sep-Oct;23(5):549-56. PMID: 11001548
Bouffet E, Philip T, Negrier C, Ffrench M, Frappaz D, Gentilhomme O, Gianella-Borradori A, Brunat-Mentigny M, Blay JY
Eur J Cancer 1997 Sep;33(10):1620-6. PMID: 9389924
Pessina GP, Paulesu L, Corradeschi F, Aldinucci C, Luzzi E, Bocci V
J Pharm Pharmacol 1996 Oct;48(10):1063-7. PMID: 8953509
Waddick KG, Finnegan DM, Chelstrom LM, Uckun FM
Leuk Lymphoma 1995 Sep;19(1-2):121-8. doi: 10.3109/10428199509059665. PMID: 8574156
May LT, Patel K, García D, Ndubuisi MI, Ferrone S, Mittelman A, Mackiewicz A, Sehgal PB
Blood 1994 Sep 15;84(6):1887-95. PMID: 8080995

Diagnosis

Chadwick DE, Jean LF, Jamal N, Messner HA, Murphy JR, Minden MD
Br J Haematol 1993 Sep;85(1):25-36. PMID: 8251407
Elliott GR, Van de Meent D, Van Dijk J
Eur J Pharmacol 1992 Apr 22;214(2-3):253-9. PMID: 1516641

Therapy

Aquino VM, Mustafa MM, Vaickus L, Wooley R, Buchanan GR
J Pediatr Hematol Oncol 1998 Sep-Oct;20(5):474-6. PMID: 9787323
Späth-Schwalbe E, Schrezenmeier H, Bornstein S, Burger K, Porzsolt F, Born J
Neuroendocrinology 1996 Mar;63(3):237-43. PMID: 8677012
Mastorakos G, Weber JS, Magiakou MA, Gunn H, Chrousos GP
J Clin Endocrinol Metab 1994 Oct;79(4):934-9. doi: 10.1210/jcem.79.4.7962300. PMID: 7962300
Mastorakos G, Chrousos GP, Weber JS
J Clin Endocrinol Metab 1993 Dec;77(6):1690-4. doi: 10.1210/jcem.77.6.8263159. PMID: 8263159
Givon T, Slavin S, Haran-Ghera N, Michalevicz R, Revel M
Blood 1992 May 1;79(9):2392-8. PMID: 1571551

Prognosis

Olencki T, Finke J, Tubbs R, Elson P, McLain D, Herzog P, Budd GT, Gunn H, Bukowski RM
J Immunother 2000 Sep-Oct;23(5):549-56. PMID: 11001548
Haverty AA, Harmey JH, Redmond HP, Bouchier-Hayes DJ
J Surg Res 1997 Apr;69(1):145-9. doi: 10.1006/jsre.1997.5036. PMID: 9202661
Mastorakos G, Chrousos GP, Weber JS
J Clin Endocrinol Metab 1993 Dec;77(6):1690-4. doi: 10.1210/jcem.77.6.8263159. PMID: 8263159
Novick D, Engelmann H, Wallach D, Leitner O, Revel M, Rubinstein M
J Chromatogr 1990 Jun 27;510:331-7. PMID: 2144854
Castell JV, Gómez-Lechón MJ, David M, Fabra R, Trullenque R, Heinrich PC
Hepatology 1990 Nov;12(5):1179-86. PMID: 1699862

Clinical prediction guides

Mastorakos G, Weber JS, Magiakou MA, Gunn H, Chrousos GP
J Clin Endocrinol Metab 1994 Oct;79(4):934-9. doi: 10.1210/jcem.79.4.7962300. PMID: 7962300
Givon T, Slavin S, Haran-Ghera N, Michalevicz R, Revel M
Blood 1992 May 1;79(9):2392-8. PMID: 1571551
Ikeda M, Ikeda U, Ohara T, Kusano E, Kano S
Am J Pathol 1992 Aug;141(2):327-34. PMID: 1497090Free PMC Article
Hill RJ, Warren MK, Stenberg P, Levin J, Corash L, Drummond R, Baker G, Levin F, Mok Y
Blood 1991 Jan 1;77(1):42-8. PMID: 1984802
Tsang KY, Finch MD, Primus FJ, Schlom J
Cancer Immunol Immunother 1991;34(1):9-16. PMID: 1836975

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