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Results: 1 to 20 of 23

1.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Pharmacologic Substance
2.

Ethanol

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. [from MeSH]

MedGen UID:
186
Concept ID:
C0001962
Pharmacologic Substance
3.

N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine

MedGen UID:
229992
Concept ID:
C1312379
Pharmacologic Substance
4.

agonists

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
5.

phenol

An antiseptic and disinfectant aromatic alcohol. [from MeSH]

MedGen UID:
74524
Concept ID:
C0070570
Pharmacologic Substance
6.

Water

Chemical compound that is liquid at room temperature and is composed two hydrogen atoms connected to an oxygen atom. [from NCI]

MedGen UID:
22697
Concept ID:
C0043047
Pharmacologic Substance
7.

Baclofen

A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. [from MeSH]

MedGen UID:
481
Concept ID:
C0004609
Pharmacologic Substance
8.

Alcohol dependence

MedGen UID:
426875
Concept ID:
CN028882
Disease or Syndrome
9.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
10.

Alcoholic Intoxication, Chronic

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) [from MeSH]

MedGen UID:
1801
Concept ID:
C0001973
Mental or Behavioral Dysfunction
11.

Chemically-Induced Disorders

Disorders caused by the intentional or unintentional ingestion or exposure to chemical substances such as PHARMACEUTICAL PREPARATIONS; NOXAE; and PESTICIDES. [from MeSH]

MedGen UID:
772538
Concept ID:
C3658339
Disease or Syndrome
12.

GABA-B Receptor Agonists

Endogenous compounds and drugs that bind to and activate GABA-B RECEPTORS. [from MeSH]

MedGen UID:
423621
Concept ID:
C2936800
Pharmacologic Substance
13.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
14.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction
15.

GABA Agonists

Endogenous compounds and drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA). [from MeSH]

MedGen UID:
116712
Concept ID:
C0242974
Pharmacologic Substance
16.

Neurotransmitter Agents

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. [from MeSH]

MedGen UID:
69321
Concept ID:
C0243051
Pharmacologic Substance
17.

Alcohol-induced organic mental disorder

Disorders related to or resulting from abuse or mis-use of alcohol. [from MeSH]

MedGen UID:
68632
Concept ID:
C0236664
Mental or Behavioral Dysfunction
18.

GABA Modulators

Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here. [from MeSH]

MedGen UID:
67022
Concept ID:
C0242976
Pharmacologic Substance
19.

GABA Agents

Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. [from MeSH]

MedGen UID:
67004
Concept ID:
C0242898
Pharmacologic Substance
20.

Substance-Related Disorders

Disorders related to substance abuse, the side effects of a medication, or toxin exposure. [from MeSH]

MedGen UID:
66746
Concept ID:
C0236969
Mental or Behavioral Dysfunction

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