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Results: 4

1.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
2.

NSC-32946

MedGen UID:
163888
Concept ID:
C0878487
Pharmacologic Substance
3.

Mitoguazone

A guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39500&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39500&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C661" NCI Thesaurus) [from PDQ]

MedGen UID:
7666
Concept ID:
C0026251
Pharmacologic Substance
4.

Methyl-gag

MedGen UID:
6351
Concept ID:
C0025716
Pharmacologic Substance

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