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Results: 1 to 20 of 41

1.

Hyperplasia

An abnormal increase in the number of cells in an organ or tissue. [from NCI]

MedGen UID:
43784
Concept ID:
C0020507
Pathologic Function
2.

Preleukemia

Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. If you have a myelodysplastic syndrome, the stem cells do not mature into healthy blood cells. This leaves less room for healthy cells, which can lead to infection, anemia, or easy bleeding. Myelodysplastic syndromes often do not cause early symptoms and are sometimes found during a routine blood test. If you have symptoms, they may include: -Shortness of breath. -Weakness or feeling tired. -Skin that is paler than usual. -Easy bruising or bleeding. -Pinpoint spots under the skin caused by bleeding. -Fever or frequent infections. Myelodysplastic syndromes are rare. People at higher risk are over 60, have had chemotherapy or radiation therapy, or have been exposed to certain chemicals. Treatment options include transfusions, drug therapy, chemotherapy, and blood or bone marrow stem cell transplants. NIH National Cancer Institute.  [from MedlinePlus]

MedGen UID:
19454
Concept ID:
C0033027
Neoplastic Process
3.

Myelodysplastic-Myeloproliferative Diseases

A category of clonal myeloid disorders that have both myelodysplastic and chronic myeloproliferative features at the time of initial presentation. (WHO, 2001) [from NCI]

MedGen UID:
226981
Concept ID:
C1301355
Neoplastic Process
4.

Myeloproliferative disorder

A clonal (malignant) proliferation of myeloid (erythroid, granulocytic, or megakaryocytic) cells originating from a primitive stem cell. [from NCI]

MedGen UID:
10147
Concept ID:
C0027022
Neoplastic Process
5.

Erythropoietin

a hormone produced in the adult kidney [from CHV]

MedGen UID:
41863
Concept ID:
C0014822
Pharmacologic Substance
6.

Eosinophilia

Abnormal increase of EOSINOPHILS in the blood, tissues or organs. [from MeSH]

MedGen UID:
41824
Concept ID:
C0014457
Disease or Syndrome
7.

leukemia

A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) [from MeSH]

MedGen UID:
9725
Concept ID:
C0023418
Neoplastic Process
8.

Diagnosis

The process of identifying a disease, such as cancer, from its signs and symptoms. [from NCI]

MedGen UID:
8354
Concept ID:
C0011900
Finding
9.

Fibrosis

The formation of fibrous tissue; fibroid or fibrous degeneration. [from NCI]

MedGen UID:
5179
Concept ID:
C0016059
Pathologic Function
10.

Leukemia

A cancer of the blood and bone marrow characterized by an abnormal proliferation of leukocytes. [from HPO]

MedGen UID:
505002
Concept ID:
CN001727
Finding
11.

Eosinophilia

A condition in which the number of eosinophils (a type of white blood cell) in the blood is greatly increased. Eosinophilia is often a response to infection or allergens (substances that cause an allergic response). [from NCI]

MedGen UID:
412195
Concept ID:
C2240374
Finding
12.

Erythroleukemia, Familial

MedGen UID:
377038
Concept ID:
C1851482
Neoplastic Process
13.

B-Symptoms

Features commonly associated with lymphoma, including fever above 38C, drenching night sweats, and weight loss of more than 10% of body mass in the previous 6 months. B symptoms are signs of a poor prognosis in patients with lymphoma. [from NCI]

MedGen UID:
353402
Concept ID:
C1706867
Finding
14.

Thymic epithelial neoplasm

MedGen UID:
220416
Concept ID:
C1266101
Neoplastic Process
15.

Proliferation

Growth and reproduction of new similar forms, e.g. cells, buds, or offspring. [from NCI]

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
16.

Dysplasia

Cells that look abnormal under a microscope but are not cancer. [from NCI]

MedGen UID:
87191
Concept ID:
C0334044
Pathologic Function
17.

Acute

Symptoms or signs that begin and worsen quickly; not chronic. [from NCI]

MedGen UID:
61381
Concept ID:
C0205178
18.

Acute myeloid leukemia, M6 type

Familial erythroleukemia is a leukemic or preleukemic state in which red cell proliferation is the predominant feature. Hematologic characteristics include particularly ineffective and hyperplastic erythropoiesis with megaloblastic components accompanied by myeloblastic proliferation of varying degree (Park et al., 2002). Park et al. (2002) discussed the evolution of the definition of 'erythroleukemia,' which is considered by most to be a subtype of acute myelogenous leukemia (AML; 601626). Controversy about the precise definition of erythroleukemia revolves around the number or percentage of erythroblasts and myeloblasts found in the bone marrow and peripheral circulation. In the French-American-British (FAB) classification system (Bennett et al., 1985), it is known as AML-M6, whereas in the revised World Health Organization (WHO) classification system (Harris et al., 1999), it is known as 'AML, not otherwise categorized' (Zini and D'Onofrio, 2004). [from OMIM]

MedGen UID:
7316
Concept ID:
C0023440
Neoplastic Process
19.

Acute Myeloid Leukemia (AML-M2)

An acute myeloid leukemia (AML) characterized by blasts with evidence of maturation to more mature neutrophils. Patients often present with anemia, neutropenia, and thrombocytopenia. AML with the t(8;21) is usually AML with maturation. This type of AML frequently responds to aggressive therapy. (WHO, 2001) [from NCI]

MedGen UID:
361829
Concept ID:
C1879321
Neoplastic Process
20.

Cirrhosis

MedGen UID:
351476
Concept ID:
C1623038
Disease or Syndrome

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