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Fetal alcohol syndrome

MedGen UID:
8820
Concept ID:
C0015923
Disease or Syndrome
Synonyms: Fetal Alcohol Syndrome; Fetal Alcohol Syndromes; Syndrome, Fetal Alcohol
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Foetal alcohol syndrome (205788004); FAS - Foetal alcohol syndrome (205788004); Fetal alcohol syndrome (205788004); FAS - Fetal alcohol syndrome (205788004)
 
Orphanet: ORPHA1915

Definition

Alcohol can harm your baby at any stage during a pregnancy. That includes the earliest stages before you even know you are pregnant. Drinking alcohol can cause a group of conditions called fetal alcohol spectrum disorders (FASDs). Effects can include physical and behavioral problems such as trouble with. -Learning and remembering. -Understanding and following directions. -Controlling emotions. -Communicating and socializing. -Daily life skills, such as feeding and bathing. Fetal alcohol syndrome is the most serious type of FASD. People with fetal alcohol syndrome have facial abnormalities, including wide-set and narrow eyes, growth problems and nervous system abnormalities. FASDs last a lifetime. There is no cure for FASDs. Treatments can help. These include medicines to help with some symptoms and behavior therapy. No one treatment is right for every child. Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal alcohol syndrome
Follow this link to review classifications for Fetal alcohol syndrome in Orphanet.

Recent clinical studies

Etiology

Urban MF, Olivier L, Viljoen D, Lombard C, Louw JG, Drotsky LM, Temmerman M, Chersich MF
Alcohol Clin Exp Res 2015 Jun;39(6):1016-26. Epub 2015 May 2 doi: 10.1111/acer.12726. [Epub ahead of print] PMID: 25941030
O'Leary LA, Ortiz L, Montgomery A, Fox DJ, Cunniff C, Ruttenber M, Breen A, Pettygrove S, Klumb D, Druschel C, Frías JL, Robinson LK, Bertrand J, Ferrara K, Kelly M, Gilboa SM, Meaney FJ; FASSNetII
Birth Defects Res A Clin Mol Teratol 2015 Mar;103(3):196-202. Epub 2015 Mar 12 doi: 10.1002/bdra.23335. [Epub ahead of print] PMID: 25761572Free PMC Article
Rangmar J, Sandberg AD, Aronson M, Fahlke C
Nord J Psychiatry 2015 Aug;69(6):472-8. Epub 2015 Feb 20 doi: 10.3109/08039488.2015.1009487. [Epub ahead of print] PMID: 25697067
Fitzpatrick JP, Latimer J, Carter M, Oscar J, Ferreira ML, Carmichael Olson H, Lucas BR, Doney R, Salter C, Try J, Hawkes G, Fitzpatrick E, Hand M, Watkins RE, Martiniuk AL, Bower C, Boulton J, Elliott EJ
J Paediatr Child Health 2015 Apr;51(4):450-7. Epub 2015 Jan 15 doi: 10.1111/jpc.12814. [Epub ahead of print] PMID: 25594247
Moberg DP, Bowser J, Burd L, Elliott AJ, Punyko J, Wilton G; Fetal Alcohol Syndrome Surveillance Program-FASSLink Team
Birth Defects Res A Clin Mol Teratol 2014 Sep;100(9):663-9. Epub 2014 Apr 16 doi: 10.1002/bdra.23245. [Epub ahead of print] PMID: 24737611Free PMC Article

Diagnosis

May PA, Keaster C, Bozeman R, Goodover J, Blankenship J, Kalberg WO, Buckley D, Brooks M, Hasken J, Gossage JP, Robinson LK, Manning M, Hoyme HE
Drug Alcohol Depend 2015 Oct 1;155:118-27. Epub 2015 Aug 14 doi: 10.1016/j.drugalcdep.2015.08.006. [Epub ahead of print] PMID: 26321671Free PMC Article
Urban MF, Olivier L, Viljoen D, Lombard C, Louw JG, Drotsky LM, Temmerman M, Chersich MF
Alcohol Clin Exp Res 2015 Jun;39(6):1016-26. Epub 2015 May 2 doi: 10.1111/acer.12726. [Epub ahead of print] PMID: 25941030
Rangmar J, Sandberg AD, Aronson M, Fahlke C
Nord J Psychiatry 2015 Aug;69(6):472-8. Epub 2015 Feb 20 doi: 10.3109/08039488.2015.1009487. [Epub ahead of print] PMID: 25697067
Fitzpatrick JP, Latimer J, Carter M, Oscar J, Ferreira ML, Carmichael Olson H, Lucas BR, Doney R, Salter C, Try J, Hawkes G, Fitzpatrick E, Hand M, Watkins RE, Martiniuk AL, Bower C, Boulton J, Elliott EJ
J Paediatr Child Health 2015 Apr;51(4):450-7. Epub 2015 Jan 15 doi: 10.1111/jpc.12814. [Epub ahead of print] PMID: 25594247
Moberg DP, Bowser J, Burd L, Elliott AJ, Punyko J, Wilton G; Fetal Alcohol Syndrome Surveillance Program-FASSLink Team
Birth Defects Res A Clin Mol Teratol 2014 Sep;100(9):663-9. Epub 2014 Apr 16 doi: 10.1002/bdra.23245. [Epub ahead of print] PMID: 24737611Free PMC Article

Therapy

May PA, Keaster C, Bozeman R, Goodover J, Blankenship J, Kalberg WO, Buckley D, Brooks M, Hasken J, Gossage JP, Robinson LK, Manning M, Hoyme HE
Drug Alcohol Depend 2015 Oct 1;155:118-27. Epub 2015 Aug 14 doi: 10.1016/j.drugalcdep.2015.08.006. [Epub ahead of print] PMID: 26321671Free PMC Article
Fitzpatrick JP, Latimer J, Carter M, Oscar J, Ferreira ML, Carmichael Olson H, Lucas BR, Doney R, Salter C, Try J, Hawkes G, Fitzpatrick E, Hand M, Watkins RE, Martiniuk AL, Bower C, Boulton J, Elliott EJ
J Paediatr Child Health 2015 Apr;51(4):450-7. Epub 2015 Jan 15 doi: 10.1111/jpc.12814. [Epub ahead of print] PMID: 25594247
Joya X, Garcia-Algar O, Salat-Batlle J, Pujades C, Vall O
Birth Defects Res A Clin Mol Teratol 2015 Mar;103(3):163-77. Epub 2014 Aug 18 doi: 10.1002/bdra.23290. [Epub ahead of print] PMID: 25131946
Smith SM, Garic A, Flentke GR, Berres ME
Birth Defects Res C Embryo Today 2014 Sep;102(3):210-20. Epub 2014 Sep 15 doi: 10.1002/bdrc.21078. [Epub ahead of print] PMID: 25219761Free PMC Article
Feltes BC, de Faria Poloni J, Nunes IJ, Bonatto D
OMICS 2014 Jun;18(6):344-63. Epub 2014 May 9 doi: 10.1089/omi.2013.0144. [Epub ahead of print] PMID: 24816220Free PMC Article

Prognosis

May PA, Keaster C, Bozeman R, Goodover J, Blankenship J, Kalberg WO, Buckley D, Brooks M, Hasken J, Gossage JP, Robinson LK, Manning M, Hoyme HE
Drug Alcohol Depend 2015 Oct 1;155:118-27. Epub 2015 Aug 14 doi: 10.1016/j.drugalcdep.2015.08.006. [Epub ahead of print] PMID: 26321671Free PMC Article
Urban MF, Olivier L, Viljoen D, Lombard C, Louw JG, Drotsky LM, Temmerman M, Chersich MF
Alcohol Clin Exp Res 2015 Jun;39(6):1016-26. Epub 2015 May 2 doi: 10.1111/acer.12726. [Epub ahead of print] PMID: 25941030
Rangmar J, Hjern A, Vinnerljung B, Strömland K, Aronson M, Fahlke C
Pediatrics 2015 Jan;135(1):e52-8. Epub 2014 Dec 22 doi: 10.1542/peds.2014-1915. [Epub ahead of print] PMID: 25535260
Stoos C, Nelsen L, Schissler KA, Elliott AJ, Kinney HC
J Child Neurol 2015 Apr;30(5):601-5. Epub 2014 Feb 20 doi: 10.1177/0883073814520976. [Epub ahead of print] PMID: 24563476
Agarwal R, Mehta C, Kumar A, Maqbool M
Pediatr Neurol 2014 Aug;51(2):282-3. Epub 2014 Apr 1 doi: 10.1016/j.pediatrneurol.2014.03.026. [Epub ahead of print] PMID: 25079579

Clinical prediction guides

May PA, Keaster C, Bozeman R, Goodover J, Blankenship J, Kalberg WO, Buckley D, Brooks M, Hasken J, Gossage JP, Robinson LK, Manning M, Hoyme HE
Drug Alcohol Depend 2015 Oct 1;155:118-27. Epub 2015 Aug 14 doi: 10.1016/j.drugalcdep.2015.08.006. [Epub ahead of print] PMID: 26321671Free PMC Article
Rangmar J, Sandberg AD, Aronson M, Fahlke C
Nord J Psychiatry 2015 Aug;69(6):472-8. Epub 2015 Feb 20 doi: 10.3109/08039488.2015.1009487. [Epub ahead of print] PMID: 25697067
Fitzpatrick JP, Latimer J, Carter M, Oscar J, Ferreira ML, Carmichael Olson H, Lucas BR, Doney R, Salter C, Try J, Hawkes G, Fitzpatrick E, Hand M, Watkins RE, Martiniuk AL, Bower C, Boulton J, Elliott EJ
J Paediatr Child Health 2015 Apr;51(4):450-7. Epub 2015 Jan 15 doi: 10.1111/jpc.12814. [Epub ahead of print] PMID: 25594247
Joya X, Garcia-Algar O, Salat-Batlle J, Pujades C, Vall O
Birth Defects Res A Clin Mol Teratol 2015 Mar;103(3):163-77. Epub 2014 Aug 18 doi: 10.1002/bdra.23290. [Epub ahead of print] PMID: 25131946
Petković G, Barišić I
Int J Environ Res Public Health 2013 Apr 16;10(4):1547-61. doi: 10.3390/ijerph10041547. PMID: 23591786Free PMC Article

Recent systematic reviews

Landgraf MN, Nothacker M, Kopp IB, Heinen F
Dtsch Arztebl Int 2013 Oct;110(42):703-10. Epub 2013 Oct 18 doi: 10.3238/arztebl.2013.0703. PMID: 24223670Free PMC Article
Landgraf MN, Nothacker M, Heinen F
Eur J Paediatr Neurol 2013 Sep;17(5):437-46. Epub 2013 Apr 22 doi: 10.1016/j.ejpn.2013.03.008. [Epub ahead of print] PMID: 23618613
Bertrand J, Floyd LL, Weber MK; Fetal Alcohol Syndrome Prevention Team, Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC)
MMWR Recomm Rep 2005 Oct 28;54(RR-11):1-14. PMID: 16251866
Eustace LW, Kang DH, Coombs D
J Obstet Gynecol Neonatal Nurs 2003 Mar-Apr;32(2):215-21. PMID: 12685673
Burd L, Moffatt ME
Public Health Rep 1994 Sep-Oct;109(5):688-93. PMID: 7938391Free PMC Article

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