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Results: 14

1.

Urokinase

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES. [from MeSH]

MedGen UID:
21790
Concept ID:
C0042071
Pharmacologic Substance
2.

Plasminogen

Plasminogen (810 aa, ~91 kDa) is encoded by the human PLG gene. This protein is involved in fibrinolysis, platelet activation and tissue remodeling. [from NCI]

MedGen UID:
10793
Concept ID:
C0032140
Pharmacologic Substance
3.

Thyroid hormone plasma membrane transport defect

MedGen UID:
396060
Concept ID:
C1861101
Disease or Syndrome
4.

Vacuolar Protein Sorting

The process of directing proteins towards the vacuole, usually using signals contained within the protein. [GOC:curators] [from GO]

MedGen UID:
275569
Concept ID:
C1519906
Molecular Function
5.

Proteolytic Processing

Generally irreversible, Proteolytic Processing involves removal of peptide segments from proteins, usually from the N- or C-terminus and often during polypeptide maturation, to regulate activity, location, or stability. [from NCI]

MedGen UID:
271417
Concept ID:
C1514570
Molecular Function
6.

Plasminogen Activator

A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation. [from MeSH]

MedGen UID:
18508
Concept ID:
C0032144
Pharmacologic Substance
7.

Does not

MedGen UID:
721427
Concept ID:
C1299585
Finding
8.

Mutant

An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or more alterations (mutations). [from NCI]

MedGen UID:
109303
Concept ID:
C0596988
Cell or Molecular Dysfunction
9.

Abbokinase

MedGen UID:
148791
Concept ID:
C0701941
Pharmacologic Substance
10.

Renokinase

MedGen UID:
147293
Concept ID:
C0701940
Pharmacologic Substance
11.

Sequence Deletion

Deletion of sequences of nucleic acids from the genetic material of an individual. [from MeSH]

MedGen UID:
102460
Concept ID:
C0162773
Cell or Molecular Dysfunction
12.

Mutagenesis Process

Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS. [from MeSH]

MedGen UID:
86969
Concept ID:
C0079866
Molecular Function
13.

Endopeptidases

nonEC category which corresponds to EC 3.4.21, EC 3.4.22, EC 3.4.23, EC 3.4.24, and EC 3.4.99. [from CRISP]

MedGen UID:
45389
Concept ID:
C0030946
Pharmacologic Substance
14.

Blood clotting factor

Endogenous substances, usually proteins, that are involved in the blood coagulation process. [from MeSH]

MedGen UID:
605
Concept ID:
C0005789
Pharmacologic Substance

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