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Results: 1 to 20 of 40

1.

Amyloidosis

A group of diseases in which protein is deposited in specific organs or throughout the body. [from CHV]

MedGen UID:
272
Concept ID:
C0002726
Disease or Syndrome
2.

Amyloidosis

The presence of `amyloid deposition` (MPATH:34) in one or more tissues. Amyloidosis may be defined as the extracellular deposition of amyloid in one or more sites of the body. [from HPO]

MedGen UID:
506428
Concept ID:
CN116766
Finding
3.

Green Tea Extract

A defined, decaffeinated green tea polyphenol mixture isolated from Camellia sinensis, a plant native to Asia, with antiviral and antioxidant activities and potential chemopreventive activity. Green tea extract contains antioxidant compounds, including flavonoids, vitamins and polyphenols such as epigallocatechin-3-gallate (EGCG), which may have antineoplastic properties. Consumption of green tea extract may confer chemopreventive protection against various cancers including those of the prostate, stomach, and esophagus. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42958&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42958&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38689" NCI Thesaurus) [from PDQ]

MedGen UID:
309941
Concept ID:
C1704263
Pharmacologic Substance
4.

Error occurred: cannot get document summary

ID:
167048

5.

Proteolysis

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah] [from GO]

MedGen UID:
108934
Concept ID:
C0597304
Molecular Function
6.

Murine

MedGen UID:
108834
Concept ID:
C0591833
Pharmacologic Substance
7.

Neurodegenerative Disorders

A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [from NCI]

MedGen UID:
101195
Concept ID:
C0524851
Disease or Syndrome
8.

Necrosis

A permanent cessation of all vital functions of a tissue. [GOC:dph] [from GO]

MedGen UID:
10199
Concept ID:
C0027540
Pathologic Function
9.

Senile plaques

Senile plaques are extracellular deposits of amyloid in the gray matter of the brain. [from HPO]

MedGen UID:
506458
Concept ID:
CN117152
Finding
10.

Neurodegeneration

Progressive loss of neural cells and tissue. [from HPO]

MedGen UID:
505144
Concept ID:
CN001976
Finding
11.

Mutant

An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or more alterations (mutations). [from NCI]

MedGen UID:
109303
Concept ID:
C0596988
Cell or Molecular Dysfunction
12.

Tumor necrosis

The lysis (breakdown) of cancer cells. This can be caused by chemical or physical means (for example, strong detergents or high-energy sound waves) or by infection with a strain of virus that can lyse cells. [from NCI]

MedGen UID:
90709
Concept ID:
C0333516
Neoplastic Process
13.

Alzheimer's disease

Alzheimer disease (AD) is characterized by dementia that typically begins with subtle and poorly recognized failure of memory and slowly becomes more severe and, eventually, incapacitating. Other common findings include confusion, poor judgment, language disturbance, agitation, withdrawal, and hallucinations. Occasionally, seizures, Parkinsonian features, increased muscle tone, myoclonus, incontinence, and mutism occur. Death usually results from general inanition, malnutrition, and pneumonia. The typical clinical duration of the disease is eight to ten years, with a range from one to 25 years. Approximately 25% of all AD is familial (i.e., =2 persons in a family have AD) of which approximately 95% is late onset (age >60-65 years) and 5% is early onset (age <65 years). [from GeneReviews]

MedGen UID:
1853
Concept ID:
C0002395
Disease or Syndrome
14.

Proteostasis Deficiencies

Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins. [from MeSH]

MedGen UID:
403490
Concept ID:
C2718000
Cell or Molecular Dysfunction
15.

Amyloid protein

extracellular glycoprotein that accumulates in certain pathological conditions, e.g., the paired helical filaments of neuritic plaques in Alzheimer's disease and Down's syndrome; use this term for both the precursor and beta form. [from CRISP]

MedGen UID:
306111
Concept ID:
C1456454
Pharmacologic Substance
16.

Plant Preparations

Material prepared from plants. [from MeSH]

MedGen UID:
183699
Concept ID:
C0949854
Pharmacologic Substance
17.

Tauopathies

Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration. [from MeSH]

MedGen UID:
181880
Concept ID:
C0949664
Disease or Syndrome
18.

(+)-Cyanidanol-3

MedGen UID:
181518
Concept ID:
C0917995
Pharmacologic Substance
19.

KB-53

MedGen UID:
163890
Concept ID:
C0878496
Pharmacologic Substance
20.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction

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