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Phobia, specific

MedGen UID:
65932
Concept ID:
C0236801
Mental or Behavioral Dysfunction
Synonyms: PHOBIA, SIMPLE
SNOMED CT: Isolated phobia (54587008); Simple phobia (54587008); Specific phobia (54587008)
 
OMIM®: 608251

Definition

An anxiety disorder characterized by an intense, irrational fear cued by the presence or anticipation of a specific object or situation. Exposure to the phobic stimulus immediately provokes an anxiety response. In adults, the specific phobia is recognized as excessive or unreasonable. [from NCI]

Recent clinical studies

Etiology

Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2016 Mar 12;3:CD011565. doi: 10.1002/14651858.CD011565.pub2. PMID: 26968204
Botella C, Pérez-Ara MÁ, Bretón-López J, Quero S, García-Palacios A, Baños RM
PLoS One 2016;11(2):e0148237. Epub 2016 Feb 17 doi: 10.1371/journal.pone.0148237. PMID: 26886423Free PMC Article
Gesi C, Abelli M, Cardini A, Lari L, Di Paolo L, Silove D, Pini S
CNS Spectr 2016 Feb;21(1):70-5. Epub 2015 Feb 23 doi: 10.1017/S1092852914000807. [Epub ahead of print] PMID: 25704393
Gregg CD, McIntosh G, Hall H, Watson H, Williams D, Hoffman CW
Spine J 2015 Dec 1;15(12):2466-71. Epub 2015 Aug 14 doi: 10.1016/j.spinee.2015.08.018. [Epub ahead of print] PMID: 26282104
Waters AM, Bradley BP, Mogg K
Psychol Med 2014 Feb;44(3):607-16. Epub 2013 Apr 17 doi: 10.1017/S0033291713000779. [Epub ahead of print] PMID: 23591000

Diagnosis

Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2016 Mar 12;3:CD011565. doi: 10.1002/14651858.CD011565.pub2. PMID: 26968204
Botella C, Pérez-Ara MÁ, Bretón-López J, Quero S, García-Palacios A, Baños RM
PLoS One 2016;11(2):e0148237. Epub 2016 Feb 17 doi: 10.1371/journal.pone.0148237. PMID: 26886423Free PMC Article
Gesi C, Abelli M, Cardini A, Lari L, Di Paolo L, Silove D, Pini S
CNS Spectr 2016 Feb;21(1):70-5. Epub 2015 Feb 23 doi: 10.1017/S1092852914000807. [Epub ahead of print] PMID: 25704393
Gregg CD, McIntosh G, Hall H, Watson H, Williams D, Hoffman CW
Spine J 2015 Dec 1;15(12):2466-71. Epub 2015 Aug 14 doi: 10.1016/j.spinee.2015.08.018. [Epub ahead of print] PMID: 26282104
Waters AM, Bradley BP, Mogg K
Psychol Med 2014 Feb;44(3):607-16. Epub 2013 Apr 17 doi: 10.1017/S0033291713000779. [Epub ahead of print] PMID: 23591000

Therapy

Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2016 Mar 12;3:CD011565. doi: 10.1002/14651858.CD011565.pub2. PMID: 26968204
Botella C, Pérez-Ara MÁ, Bretón-López J, Quero S, García-Palacios A, Baños RM
PLoS One 2016;11(2):e0148237. Epub 2016 Feb 17 doi: 10.1371/journal.pone.0148237. PMID: 26886423Free PMC Article
Fox E, Zougkou K, Ashwin C, Cahill S
J Behav Ther Exp Psychiatry 2015 Dec;49(Pt A):84-93. Epub 2015 May 13 doi: 10.1016/j.jbtep.2015.05.001. [Epub ahead of print] PMID: 26060177Free PMC Article
Acheson DT, Feifel D, Kamenski M, Mckinney R, Risbrough VB
Depress Anxiety 2015 Jun;32(6):400-7. Epub 2015 Mar 31 doi: 10.1002/da.22362. [Epub ahead of print] PMID: 25826649
Wiemer J, Schulz SM, Reicherts P, Glotzbach-Schoon E, Andreatta M, Pauli P
Soc Cogn Affect Neurosci 2015 Jul;10(7):969-77. Epub 2014 Nov 18 doi: 10.1093/scan/nsu142. [Epub ahead of print] PMID: 25411452Free PMC Article

Prognosis

Botella C, Pérez-Ara MÁ, Bretón-López J, Quero S, García-Palacios A, Baños RM
PLoS One 2016;11(2):e0148237. Epub 2016 Feb 17 doi: 10.1371/journal.pone.0148237. PMID: 26886423Free PMC Article
Gregg CD, McIntosh G, Hall H, Watson H, Williams D, Hoffman CW
Spine J 2015 Dec 1;15(12):2466-71. Epub 2015 Aug 14 doi: 10.1016/j.spinee.2015.08.018. [Epub ahead of print] PMID: 26282104
Busscher B, Spinhoven P, de Geus EJ
Psychosom Med 2015 Sep;77(7):762-74. doi: 10.1097/PSY.0000000000000209. PMID: 26186430
Münsterkötter AL, Notzon S, Redlich R, Grotegerd D, Dohm K, Arolt V, Kugel H, Zwanzger P, Dannlowski U
Depress Anxiety 2015 Sep;32(9):656-63. Epub 2015 Jun 26 doi: 10.1002/da.22382. [Epub ahead of print] PMID: 26115440
Waters AM, Bradley BP, Mogg K
Psychol Med 2014 Feb;44(3):607-16. Epub 2013 Apr 17 doi: 10.1017/S0033291713000779. [Epub ahead of print] PMID: 23591000

Clinical prediction guides

Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2016 Mar 12;3:CD011565. doi: 10.1002/14651858.CD011565.pub2. PMID: 26968204
Costa DS, Smith AB, Fardell JE
Support Care Cancer 2016 Jan;24(1):1-3. Epub 2015 Sep 16 doi: 10.1007/s00520-015-2943-y. [Epub ahead of print] PMID: 26377307
Custers JA, Gielissen MF, Janssen SH, de Wilt JH, Prins JB
Support Care Cancer 2016 Feb;24(2):555-62. Epub 2015 Jun 25 doi: 10.1007/s00520-015-2808-4. [Epub ahead of print] PMID: 26108170Free PMC Article
Gesi C, Abelli M, Cardini A, Lari L, Di Paolo L, Silove D, Pini S
CNS Spectr 2016 Feb;21(1):70-5. Epub 2015 Feb 23 doi: 10.1017/S1092852914000807. [Epub ahead of print] PMID: 25704393
Waters AM, Bradley BP, Mogg K
Psychol Med 2014 Feb;44(3):607-16. Epub 2013 Apr 17 doi: 10.1017/S0033291713000779. [Epub ahead of print] PMID: 23591000

Recent systematic reviews

Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2016 Mar 12;3:CD011565. doi: 10.1002/14651858.CD011565.pub2. PMID: 26968204
Olthuis JV, Watt MC, Bailey K, Hayden JA, Stewart SH
Cochrane Database Syst Rev 2015 Mar 5;(3):CD011565. doi: 10.1002/14651858.CD011565. PMID: 25742186
Denkinger MD, Lukas A, Nikolaus T, Hauer K
Am J Geriatr Psychiatry 2015 Jan;23(1):72-86. Epub 2014 Mar 15 doi: 10.1016/j.jagp.2014.03.002. [Epub ahead of print] PMID: 24745560
Iglesias A, Iglesias A, Iglesias A
Am J Clin Hypn 2013 Oct;56(2):143-51. PMID: 24665816
Podină IR, Koster EH, Philippot P, Dethier V, David DO
Clin Psychol Rev 2013 Dec;33(8):1172-83. Epub 2013 Oct 9 doi: 10.1016/j.cpr.2013.10.002. [Epub ahead of print] PMID: 24185091

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