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Results: 1 to 20 of 26

1.

bisindolylmaleimide

MedGen UID:
74003
Concept ID:
C0256431
Pharmacologic Substance
2.

Insulin resistance

Decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia. [from NCI]

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
3.

wortmannin

A potent fungal metabolite isolated from Penicillium wortmannin that selectively inhibits phosphatidylinositol 3-kinase and affects the signal transduction pathway. (NCI) [from NCI]

MedGen UID:
37076
Concept ID:
C0078517
Pharmacologic Substance
4.

triacsin C

MedGen UID:
35491
Concept ID:
C0076992
Pharmacologic Substance
5.

Obesity

Obesity means having too much body fat. It is different from being overweight, which means weighing too much. The weight may come from muscle, bone, fat, and/or body water. Both terms mean that a person's weight is greater than what's considered healthy for his or her height. . Obesity occurs over time when you eat more calories than you use. The balance between calories-in and calories-out differs for each person. Factors that might affect your weight include your genetic makeup, overeating, eating high-fat foods, and not being physically active. . Being obese increases your risk of diabetes, heart disease, stroke, arthritis, and some cancers. If you are obese, losing even 5 to 10 percent of your weight can delay or prevent some of these diseases. For example, that means losing 10 to 20 pounds if you weigh 200 pounds. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
18127
Concept ID:
C0028754
Disease or Syndrome
6.

Necrosis

A permanent cessation of all vital functions of a tissue. [GOC:dph] [from GO]

MedGen UID:
10199
Concept ID:
C0027540
Pathologic Function
7.

Inflammation

A microscopic finding indicating the presence of acute, subacute or chronic inflammation in a tissue sample. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
8.

Insulin

Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism. [from NCI]

MedGen UID:
5827
Concept ID:
C0021641
Pharmacologic Substance
9.

Fetal anticonvulsant syndrome

MedGen UID:
798104
Concept ID:
CN204838
Disease or Syndrome
10.

Insulin resistance

Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
504630
Concept ID:
CN000801
Finding
11.

Error occurred: cannot get document summary

ID:
449670

12.

Obesity

MedGen UID:
368429
Concept ID:
C1963185
Finding
13.

Dystonia 10

Familial paroxysmal kinesigenic dyskinesia (referred to as familial PKD in this entry) is characterized by unilateral or bilateral involuntary movements precipitated by other sudden movements such as standing up from a sitting position, being startled, or changes in velocity; attacks include combinations of dystonia, choreoathetosis, and ballism, are sometimes preceded by an aura, and do not involve loss of consciousness. Attacks can be as frequent as 100 per day to as few as one per month. Attacks are usually a few seconds to five minutes in duration but can last several hours. Age of onset, severity and combinations of symptoms vary. Age of onset, typically in childhood and adolescence, ranges from four months to 57 years. The phenotype of PKD can include benign familial infantile epilepsy (BFIE), infantile convulsions and choreoathetosis (ICCA), hemiplegic migraine, migraine with and without aura, and episodic ataxia. Familial PKD is predominantly seen in males. [from GeneReviews]

MedGen UID:
358268
Concept ID:
C1868682
Disease or Syndrome
14.

Acyl-CoA thioester hydrolase, long-chain, 1

MedGen UID:
351308
Concept ID:
C1865144
15.

Docosahexaenoic acid

A polyunsaturated very long-chain fatty acid with a 22-carbon backbone and 6 double bonds. Four separate isomers can be called by this name. [from NCI]

MedGen UID:
107523
Concept ID:
C0556150
Pharmacologic Substance
16.

Generalized

Inverse of Specializes. Only included as a derived relationship. [from HL7]

MedGen UID:
104661
Concept ID:
C0205246
17.

Localized

Restricted to the site of origin, without evidence of spread. [from NCI_NCI-GLOSS]

MedGen UID:
98236
Concept ID:
C0392752
18.

Oncolysis

The lysis (breakdown) of cancer cells. This can be caused by chemical or physical means (for example, strong detergents or high-energy sound waves) or by infection with a strain of virus that can lyse cells. [from NCI]

MedGen UID:
90709
Concept ID:
C0333516
Neoplastic Process
19.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
20.

Mitogens

any of a class of substances that stimulate mitosis and cell transformation, especially lymphocyte transformation. [from CRISP]

MedGen UID:
7665
Concept ID:
C0026249
Pharmacologic Substance

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