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Results: 3

1.

zaleplon

A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding. [from NCI]

MedGen UID:
117853
Concept ID:
C0251504
Pharmacologic Substance
2.

Insomnia

MedGen UID:
409589
Concept ID:
C1963237
Finding
3.

Insomnia

Insomnia is a common sleep disorder. If you have it, you may have trouble falling asleep, staying asleep, or both. As a result, you may get too little sleep or have poor-quality sleep. You may not feel refreshed when you wake up. Symptoms of insomnia include:: -Lying awake for a long time before you fall asleep. - Sleeping for only short periods. -Being awake for much of the night. -Feeling as if you haven't slept at all. -Waking up too early. Your doctor will diagnose insomnia based on your medical and sleep histories and a physical exam. He or she also may recommend a sleep study. A sleep study measures how well you sleep and how your body responds to sleep problems. Treatments include lifestyle changes, counseling, and medicines. NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
214589
Concept ID:
C0917801
Sign or Symptom

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