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Abnormal motor neuron morphology

MedGen UID:
446444
Concept ID:
CN002224
Finding
 

Definition

Any structural anomal that affects the motor neuron. [from HPO]

Recent clinical studies

Etiology

Liu X, Chen J, Liu W, Li X, Chen Q, Liu T, Gao S, Deng M
Neurogenetics 2015 Jul;16(3):223-31. Epub 2015 Apr 26 doi: 10.1007/s10048-015-0448-y. [Epub ahead of print] PMID: 25912081
Sleutjes BT, Montfoort I, van Doorn PA, Visser GH, Blok JH
Clin Neurophysiol 2015 Jul;126(7):1440-5. Epub 2014 Oct 30 doi: 10.1016/j.clinph.2014.10.145. [Epub ahead of print] PMID: 25468238
Saporta MA, Dang V, Volfson D, Zou B, Xie XS, Adebola A, Liem RK, Shy M, Dimos JT
Exp Neurol 2015 Jan;263:190-9. Epub 2014 Oct 30 doi: 10.1016/j.expneurol.2014.10.005. [Epub ahead of print] PMID: 25448007Free PMC Article
Yamashita T, Kwak S
Brain Res 2014 Oct 10;1584:28-38. Epub 2013 Dec 16 doi: 10.1016/j.brainres.2013.12.011. [Epub ahead of print] PMID: 24355598
Benatar M, Wuu J, Fernandez C, Weihl CC, Katzen H, Steele J, Oskarsson B, Taylor JP
Neurology 2013 May 14;80(20):1874-80. Epub 2013 May 1 doi: 10.1212/WNL.0b013e3182929fc3. [Epub ahead of print] PMID: 23635965Free PMC Article

Diagnosis

Sleutjes BT, Montfoort I, van Doorn PA, Visser GH, Blok JH
Clin Neurophysiol 2015 Jul;126(7):1440-5. Epub 2014 Oct 30 doi: 10.1016/j.clinph.2014.10.145. [Epub ahead of print] PMID: 25468238
Viollet L, Melki J
Handb Clin Neurol 2013;113:1395-411. doi: 10.1016/B978-0-444-59565-2.00010-1. PMID: 23622363
Furtula J, Johnsen B, Frandsen J, Rodell A, Christensen PB, Pugdahl K, Fuglsang-Frederiksen A
J Neurol 2013 Jun;260(6):1535-44. Epub 2013 Jan 9 doi: 10.1007/s00415-012-6824-8. [Epub ahead of print] PMID: 23299622
Nagao S, Yokota O, Nanba R, Takata H, Haraguchi T, Ishizu H, Ikeda C, Takeda N, Oshima E, Sakane K, Terada S, Ihara Y, Uchitomi Y
J Neurol Sci 2012 Dec 15;323(1-2):147-53. Epub 2012 Sep 29 doi: 10.1016/j.jns.2012.09.005. [Epub ahead of print] PMID: 23026537
Fisher KM, Zaaimi B, Williams TL, Baker SN, Baker MR
Brain 2012 Sep;135(Pt 9):2849-64. Epub 2012 Jun 22 doi: 10.1093/brain/aws150. [Epub ahead of print] PMID: 22734124Free PMC Article

Therapy

Ando H, Mochiki E, Ohno T, Yanai M, Toyomasu Y, Ogata K, Tabe Y, Aihara R, Nakabayashi T, Asao T, Kuwano H
World J Gastroenterol 2014 Nov 14;20(42):15691-702. doi: 10.3748/wjg.v20.i42.15691. PMID: 25400453Free PMC Article
Jee MK, Jung JS, Im YB, Jung SJ, Kang SK
Hum Gene Ther 2012 May;23(5):508-20. Epub 2012 Apr 23 doi: 10.1089/hum.2011.121. [Epub ahead of print] PMID: 22182208
Ido A, Fukuyama H, Urushitani M
Int J Mol Sci 2011;12(10):6980-7003. Epub 2011 Oct 19 doi: 10.3390/ijms12106980. PMID: 22072931Free PMC Article
Seo JS, Leem YH, Lee KW, Kim SW, Lee JK, Han PL
J Alzheimers Dis 2010;21(1):263-76. doi: 10.3233/JAD-2010-091528. PMID: 20421695
Doi H, Kikuchi H, Murai H, Kawano Y, Shigeto H, Ohyagi Y, Kira J
Neurology 2006 Nov 28;67(10):1894-5. doi: 10.1212/01.wnl.0000244489.65670.9f. PMID: 17130437

Prognosis

Magrané J, Cortez C, Gan WB, Manfredi G
Hum Mol Genet 2014 Mar 15;23(6):1413-24. Epub 2013 Oct 23 doi: 10.1093/hmg/ddt528. [Epub ahead of print] PMID: 24154542Free PMC Article
Viollet L, Melki J
Handb Clin Neurol 2013;113:1395-411. doi: 10.1016/B978-0-444-59565-2.00010-1. PMID: 23622363
Qiu L, Qiao T, Beers M, Tan W, Wang H, Yang B, Xu Z
Mol Neurodegener 2013 Jan 3;8:1. doi: 10.1186/1750-1326-8-1. [Epub ahead of print] PMID: 23281774Free PMC Article
Martínez-Hernández R, Bernal S, Also-Rallo E, Alías L, Barceló MJ, Hereu M, Esquerda JE, Tizzano EF
J Pathol 2013 Jan;229(1):49-61. doi: 10.1002/path.4080. PMID: 22847626
Nagao S, Yokota O, Nanba R, Takata H, Haraguchi T, Ishizu H, Ikeda C, Takeda N, Oshima E, Sakane K, Terada S, Ihara Y, Uchitomi Y
J Neurol Sci 2012 Dec 15;323(1-2):147-53. Epub 2012 Sep 29 doi: 10.1016/j.jns.2012.09.005. [Epub ahead of print] PMID: 23026537

Clinical prediction guides

Carrasco DI, Bahr BA, Seburn KL, Pinter MJ
Exp Neurol 2016 Apr;278:116-26. Epub 2016 Feb 4 doi: 10.1016/j.expneurol.2016.02.002. [Epub ahead of print] PMID: 26853136Free PMC Article
Saporta MA, Dang V, Volfson D, Zou B, Xie XS, Adebola A, Liem RK, Shy M, Dimos JT
Exp Neurol 2015 Jan;263:190-9. Epub 2014 Oct 30 doi: 10.1016/j.expneurol.2014.10.005. [Epub ahead of print] PMID: 25448007Free PMC Article
Qiu L, Qiao T, Beers M, Tan W, Wang H, Yang B, Xu Z
Mol Neurodegener 2013 Jan 3;8:1. doi: 10.1186/1750-1326-8-1. [Epub ahead of print] PMID: 23281774Free PMC Article
Fisher KM, Zaaimi B, Williams TL, Baker SN, Baker MR
Brain 2012 Sep;135(Pt 9):2849-64. Epub 2012 Jun 22 doi: 10.1093/brain/aws150. [Epub ahead of print] PMID: 22734124Free PMC Article
Spalloni A, Origlia N, Sgobio C, Trabalza A, Nutini M, Berretta N, Bernardi G, Domenici L, Ammassari-Teule M, Longone P
Cereb Cortex 2011 Apr;21(4):796-805. Epub 2010 Aug 23 doi: 10.1093/cercor/bhq152. [Epub ahead of print] PMID: 20732897

Recent systematic reviews

Ramaswamy S, Shannon KM, Kordower JH
Cell Transplant 2007;16(3):301-12. PMID: 17503740
Gouveia RG, Pinto A, Evangelista T, Atalaia A, Conceição I, de Carvalho M
Amyotroph Lateral Scler 2006 Mar;7(1):57-60. doi: 10.1080/14660820510012031. PMID: 16546760
Warren NM, Piggott MA, Perry EK, Burn DJ
Brain 2005 Feb;128(Pt 2):239-49. Epub 2005 Jan 13 doi: 10.1093/brain/awh391. [Epub ahead of print] PMID: 15649952
Vodusek DB
Mov Disord 2001 Jul;16(4):600-7. PMID: 11481682

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