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Results: 4

1.

Alcohol dependence

For most adults, moderate alcohol use is probably not harmful. However, about 18 million adult Americans are alcoholics or have alcohol problems. Alcoholism is a disease with four main features:: - Craving - a strong need to drink. - Loss of control - not being able to stop drinking once you've started. - Physical dependence - withdrawal symptoms, such as nausea, sweating, or shakiness when you don't drink. - Tolerance - the need to drink greater amounts of alcohol to feel the same effect. Alcoholism carries many serious dangers. Heavy drinking can increase the risk of certain cancers. It can cause damage to the liver, brain, and other organs. Drinking during pregnancy can harm your baby. Alcoholism also increases the risk of death from car crashes, injuries, homicide, and suicide. If you want to stop drinking, there is help. Start by talking to your health care provider. Medicines, counseling, and support groups may help you to stop drinking. NIH: National Institute on Alcohol Abuse and Alcoholism.  [from MedlinePlus]

MedGen UID:
1801
Concept ID:
C0001973
Mental or Behavioral Dysfunction
2.

Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C). [from ORDO]

MedGen UID:
798230
Concept ID:
CN205305
Disease or Syndrome
3.

Anxiety

MedGen UID:
409544
Concept ID:
C1963064
Finding
4.

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes (Reif and Lesch, 2003). Fullerton et al. (2003) stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; 167870), which is a subtype of anxiety disorder. [from OMIM]

MedGen UID:
335849
Concept ID:
C1842981
Disease or Syndrome

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