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Results: 19

1.

Necrosis

A permanent cessation of all vital functions of a tissue. [GOC:dph] [from GO]

MedGen UID:
10199
Concept ID:
C0027540
Pathologic Function
2.

Migraine

Migraine is a chronic neurological disorder characterized by episodic attacks of headache and associated symptoms. [from HPO]

MedGen UID:
505085
Concept ID:
CN001878
Finding
3.

Tumor necrosis

The lysis (breakdown) of cancer cells. This can be caused by chemical or physical means (for example, strong detergents or high-energy sound waves) or by infection with a strain of virus that can lyse cells. [from NCI]

MedGen UID:
90709
Concept ID:
C0333516
Neoplastic Process
4.

Migraine

Migraine is the most common type of chronic, episodic headache, as summarized by Featherstone (1985). One locus for migraine with or without aura (MGR1) has been identified on chromosome 4q24. Other loci for migraine have been identified on 6p21.1-p12.2 (MGR3; 607498), 14q21.2-q22.3 (MGR4; 607501), 19p13 (MGR5; 607508), 1q31 (MGR6; 607516), 15q11-q13 (MGR7; 609179), 5q21 (with or without aura, MGR8, 609570; with aura, MGR9, 609670), 17p13 (MGR10; 610208), 18q12 (MGR11; 610209), 10q22-q23 (MGR12; 611706), and the X chromosome (MGR2; 300125). Mutation in the KCNK18 gene (613655) on chromosome 10q25 causes migraine with aura (MGR13; 613656). A subtype of autosomal dominant migraine with aura (MA), familial hemiplegic migraine (FHM; see 141500), is caused by mutation in the CACNA1A gene (601011) on chromosome 19p13 (FHM1; 141500), by mutation in the ATP1A2 gene (182340) on chromosome 1q21 (FHM2; 602481), or by mutation in the SCN1A gene (182389) on chromosome 2q24 (FHM3; 609634). Another locus for FHM has been mapped to chromosome 1q31 (FHM4; see 607516). There is evidence that a polymorphism in the estrogen receptor gene (ESR1; 133430.0005) and a polymorphism in the TNF gene (191160.0004) may confer susceptibility to migraine. A polymorphism in the endothelin receptor type A gene (EDNRA; 131243.0001) may confer resistance to migraine. [from OMIM]

MedGen UID:
57451
Concept ID:
C0149931
Disease or Syndrome
5.

Recurrent unilateral pulsatile headaches, not preceded or accompanied by an aura, in attacks lasting 4-72 hours. It is characterized by PAIN of moderate to severe intensity; aggravated by physical activity; and associated with NAUSEA and / or PHOTOPHOBIA and PHONOPHOBIA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) [from MeSH]

MedGen UID:
137899
Concept ID:
C0338480
6.

Auras

Sensations experienced immediately prior to the onset of a seizure, migraine headache, or other nervous system disorder symptoms. Also, the patient's recognition of the beginning of an epileptic attack. Use PARAPSYCHOLOGY or PARAPSYCHOLOGICAL PHENOMENA to access references on psychic auras and halos. [from PSY]

MedGen UID:
65921
Concept ID:
C0236018
Finding
7.

Migraine with aura

A subtype of migraine disorder, characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred VISION; HALLUCINATIONS; VERTIGO; NUMBNESS; and difficulty in concentrating and speaking. Aura is usually followed by features of the COMMON MIGRAINE, such as PHOTOPHOBIA; PHONOPHOBIA; and NAUSEA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) [from MeSH]

MedGen UID:
57822
Concept ID:
C0154723
Disease or Syndrome
8.

Migraine without aura

Repeated headache attacks lasting 4-72 h fulfilling at least two of the following criteria: 1) unilateral location, 2) pulsating quality, 3) moderate or severe pain intensity, and 4) aggravation by or causing avoidance of routine physical activity such as climbing stairs. Headache attacks are commonly accompanied by nausea, vomiting, photophobia, or phonophobia. [from HPO]

MedGen UID:
505090
Concept ID:
CN001884
Finding
9.

Migraine with aura

A type of `migraine` (HP:0002076) in which there is an aura characterized by focal neurological phenomena that usually proceed, but may accompany or occur in the absence of, the headache. The symptoms of an aura may include fully reversible visual, sensory, and speech symptoms but not motor weakness. Visual symptoms may include flickering lights, spots and lines and/or loss of vision and/or unilateral sensory symptoms such as paresthesias or numbness. At least one of the symptoms of an aura develops gradually over 5 or more minutes and/or different symptoms occur in succession. [from HPO]

MedGen UID:
505086
Concept ID:
CN001879
Finding
10.

Headache Disorders, Primary

Conditions in which the primary symptom is HEADACHE and the headache cannot be attributed to any known causes. [from MeSH]

MedGen UID:
297452
Concept ID:
C1565106
Disease or Syndrome
11.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
12.

MedGen UID:
156011
Concept ID:
C0752149
13.

Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) [from MeSH]

MedGen UID:
140743
Concept ID:
C0393735
14.

Disorder of nervous system

A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. [from NCI]

MedGen UID:
14336
Concept ID:
C0027765
Disease or Syndrome
15.

Disorder of brain

A non-neoplastic or neoplastic disorder that affects the brain. [from NCI]

MedGen UID:
14214
Concept ID:
C0006111
Disease or Syndrome
16.

Disorder of the central nervous system

Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord. [from MeSH]

MedGen UID:
3306
Concept ID:
C0007682
Disease or Syndrome
17.

Brain Pathology

Acute or chronic brain damage or dysfunction. [from MeSH]

MedGen UID:
2340
Concept ID:
C0006119
Pathologic Function
18.

Migraine variant with headache

MedGen UID:
677057
Concept ID:
C0744644
Disease or Syndrome
19.

Migraine with or without aura 3

MedGen UID:
375283
Concept ID:
C1843782
Finding

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