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Premature ejaculation

MedGen UID:
452112
Concept ID:
C0033038
Mental or Behavioral Dysfunction
Synonyms: Ejaculatio Praecox; Ejaculatio Praecoxs; Ejaculation, Premature; Ejaculations, Premature; Praecox, Ejaculatio; Praecoxs, Ejaculatio; Premature Ejaculation; Premature Ejaculations
SNOMED CT: Premature orgasm - male (44001008); Ejaculates too soon (44001008); Premature ejaculation (44001008); Ejaculatio praecox (44001008)
 
HPO: HP:0012876

Definition

The emission of SEMEN and seminal fluid during the act of preparation for sexual intercourse, i.e. before there is penetration, or shortly after penetration. [from MeSH]

Recent clinical studies

Etiology

Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO
J Sex Med 2014 Jun;11(6):1423-41. Epub 2014 May 22 doi: 10.1111/jsm.12524. [Epub ahead of print] PMID: 24848805
Xu G, Jiang HW, Fang J, Wen H, Gu B, Liu J, Zhang LM, Ding Q, Zhang YF
J Clin Pharm Ther 2014 Feb;39(1):84-90. Epub 2013 Dec 9 doi: 10.1111/jcpt.12115. [Epub ahead of print] PMID: 24313633
Shinghal R, Barnes A, Mahar KM, Stier B, Giancaterino L, Condreay LD, Black L, McCallum SW
J Sex Med 2013 Oct;10(10):2506-17. Epub 2013 Aug 12 doi: 10.1111/jsm.12272. [Epub ahead of print] PMID: 23937679
Lee WK, Lee SH, Cho ST, Lee YS, Oh CY, Yoo C, Cho JS, Lee SK, Yang DY
J Sex Med 2013 Nov;10(11):2832-41. Epub 2013 Aug 12 doi: 10.1111/jsm.12287. [Epub ahead of print] PMID: 23937271
McMahon CG, Giuliano F, Dean J, Hellstrom WJ, Bull S, Tesfaye F, Sharma O, Rivas DA, Aquilina JW
J Sex Med 2013 Sep;10(9):2312-25. Epub 2013 Jul 11 doi: 10.1111/jsm.12236. [Epub ahead of print] PMID: 23845016

Diagnosis

Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO
J Sex Med 2014 Jun;11(6):1423-41. Epub 2014 May 22 doi: 10.1111/jsm.12524. [Epub ahead of print] PMID: 24848805
Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO
J Sex Med 2014 Jun;11(6):1392-422. Epub 2014 May 22 doi: 10.1111/jsm.12504. [Epub ahead of print] PMID: 24848686
Xu G, Jiang HW, Fang J, Wen H, Gu B, Liu J, Zhang LM, Ding Q, Zhang YF
J Clin Pharm Ther 2014 Feb;39(1):84-90. Epub 2013 Dec 9 doi: 10.1111/jcpt.12115. [Epub ahead of print] PMID: 24313633
Shinghal R, Barnes A, Mahar KM, Stier B, Giancaterino L, Condreay LD, Black L, McCallum SW
J Sex Med 2013 Oct;10(10):2506-17. Epub 2013 Aug 12 doi: 10.1111/jsm.12272. [Epub ahead of print] PMID: 23937679
Lee WK, Lee SH, Cho ST, Lee YS, Oh CY, Yoo C, Cho JS, Lee SK, Yang DY
J Sex Med 2013 Nov;10(11):2832-41. Epub 2013 Aug 12 doi: 10.1111/jsm.12287. [Epub ahead of print] PMID: 23937271

Therapy

Akasheh G, Sirati L, Noshad Kamran AR, Sepehrmanesh Z
Urology 2014 Apr;83(4):800-4. Epub 2014 Feb 12 doi: 10.1016/j.urology.2013.12.004. [Epub ahead of print] PMID: 24529582
Xu G, Jiang HW, Fang J, Wen H, Gu B, Liu J, Zhang LM, Ding Q, Zhang YF
J Clin Pharm Ther 2014 Feb;39(1):84-90. Epub 2013 Dec 9 doi: 10.1111/jcpt.12115. [Epub ahead of print] PMID: 24313633
Shinghal R, Barnes A, Mahar KM, Stier B, Giancaterino L, Condreay LD, Black L, McCallum SW
J Sex Med 2013 Oct;10(10):2506-17. Epub 2013 Aug 12 doi: 10.1111/jsm.12272. [Epub ahead of print] PMID: 23937679
Lee WK, Lee SH, Cho ST, Lee YS, Oh CY, Yoo C, Cho JS, Lee SK, Yang DY
J Sex Med 2013 Nov;10(11):2832-41. Epub 2013 Aug 12 doi: 10.1111/jsm.12287. [Epub ahead of print] PMID: 23937271
McMahon CG, Giuliano F, Dean J, Hellstrom WJ, Bull S, Tesfaye F, Sharma O, Rivas DA, Aquilina JW
J Sex Med 2013 Sep;10(9):2312-25. Epub 2013 Jul 11 doi: 10.1111/jsm.12236. [Epub ahead of print] PMID: 23845016

Prognosis

Yazici CM, Sarifakioglu B, Guzelant A, Turker P, Ates O
Int Urol Nephrol 2013 Jun;45(3):659-67. Epub 2013 Mar 30 doi: 10.1007/s11255-013-0411-5. [Epub ahead of print] PMID: 23543125
Yang C, Tang K, Wang B
Urol Int 2013;90(2):214-8. Epub 2012 Nov 27 doi: 10.1159/000343736. [Epub ahead of print] PMID: 23207833
Limoncin E, Tomassetti M, Gravina GL, Ciocca G, Carosa E, Di Sante S, Gentile V, Mirone V, Montorsi F, Lenzi A, Jannini EA
J Urol 2013 May;189(5):1830-5. Epub 2012 Nov 6 doi: 10.1016/j.juro.2012.11.007. [Epub ahead of print] PMID: 23142691
Luján S, García-Fadrique G, Morales G, Morera J, Broseta E, Jiménez-Cruz JF
J Sex Med 2012 Feb;9(2):404-10. Epub 2011 Dec 21 doi: 10.1111/j.1743-6109.2011.02571.x. [Epub ahead of print] PMID: 22188942
Serefoglu EC, Yaman O, Cayan S, Asci R, Orhan I, Usta MF, Ekmekcioglu O, Kendirci M, Semerci B, Kadioglu A
J Sex Med 2011 Apr;8(4):1177-85. Epub 2011 Jan 26 doi: 10.1111/j.1743-6109.2010.02183.x. [Epub ahead of print] PMID: 21269396

Clinical prediction guides

Lee JH
J Sex Med 2014 Jun;11(6):1512-8. Epub 2014 Feb 17 doi: 10.1111/jsm.12461. [Epub ahead of print] PMID: 24528521
Xu G, Jiang HW, Fang J, Wen H, Gu B, Liu J, Zhang LM, Ding Q, Zhang YF
J Clin Pharm Ther 2014 Feb;39(1):84-90. Epub 2013 Dec 9 doi: 10.1111/jcpt.12115. [Epub ahead of print] PMID: 24313633
Tang KL, Wang BL, Yang L, Li LM, Zhou Y, Yang CH
Bosn J Basic Med Sci 2013 Nov;13(4):248-52. PMID: 24289761
Lee WK, Lee SH, Cho ST, Lee YS, Oh CY, Yoo C, Cho JS, Lee SK, Yang DY
J Sex Med 2013 Nov;10(11):2832-41. Epub 2013 Aug 12 doi: 10.1111/jsm.12287. [Epub ahead of print] PMID: 23937271
McMahon CG, Giuliano F, Dean J, Hellstrom WJ, Bull S, Tesfaye F, Sharma O, Rivas DA, Aquilina JW
J Sex Med 2013 Sep;10(9):2312-25. Epub 2013 Jul 11 doi: 10.1111/jsm.12236. [Epub ahead of print] PMID: 23845016

Recent systematic reviews

Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO
J Sex Med 2014 Jun;11(6):1423-41. Epub 2014 May 22 doi: 10.1111/jsm.12524. [Epub ahead of print] PMID: 24848805
Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO
J Sex Med 2014 Jun;11(6):1392-422. Epub 2014 May 22 doi: 10.1111/jsm.12504. [Epub ahead of print] PMID: 24848686
Xia JD, Han YF, Zhou LH, Chen Y, Dai YT
Asian J Androl 2013 Jul;15(4):497-502. Epub 2013 May 27 doi: 10.1038/aja.2012.174. [Epub ahead of print] PMID: 23708465Free PMC Article
Shaeer O
J Sex Med 2013 Jul;10(7):1882-8. Epub 2013 May 13 doi: 10.1111/jsm.12187. [Epub ahead of print] PMID: 23668379
Pu C, Yang L, Liu L, Yuan H, Wei Q, Han P
Urology 2013 Apr;81(4):799-804. Epub 2013 Feb 20 doi: 10.1016/j.urology.2012.12.028. [Epub ahead of print] PMID: 23434101

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