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Mild

MedGen UID:
422477
Concept ID:
C2945599
Synonyms: MILD; Mildly; Slight
SNOMED CT: Mild (255604002)
 
HPO: HP:0012825

Definition

The second level of severity in an ordered list based on a five-level scale of minimal, mild, moderate, marked, and severe. [from NCI]

Recent clinical studies

Etiology

Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA
Am J Psychiatry 2014 May 1;171(5):572-81. doi: 10.1176/appi.ajp.2014.13060821. PMID: 24700290Free PMC Article
Mirelman A, Weiss A, Buchman AS, Bennett DA, Giladi N, Hausdorff JM
J Am Geriatr Soc 2014 Apr;62(4):673-8. Epub 2014 Mar 17 doi: 10.1111/jgs.12734. [Epub ahead of print] PMID: 24635699Free PMC Article
Hanganu A, Bedetti C, Degroot C, Mejia-Constain B, Lafontaine AL, Soland V, Chouinard S, Bruneau MA, Mellah S, Belleville S, Monchi O
Brain 2014 Apr;137(Pt 4):1120-9. Epub 2014 Mar 10 doi: 10.1093/brain/awu036. [Epub ahead of print] PMID: 24613932
Christopher L, Marras C, Duff-Canning S, Koshimori Y, Chen R, Boileau I, Segura B, Monchi O, Lang AE, Rusjan P, Houle S, Strafella AP
Brain 2014 Feb;137(Pt 2):565-75. Epub 2013 Dec 12 doi: 10.1093/brain/awt337. [Epub ahead of print] PMID: 24334314
Schneider DF, Burke JF, Ojomo KA, Clark N, Mazeh H, Sippel RS, Chen H
Ann Surg Oncol 2013 Dec;20(13):4205-11. Epub 2013 Aug 14 doi: 10.1245/s10434-013-3190-4. [Epub ahead of print] PMID: 23943034

Diagnosis

Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA
Am J Psychiatry 2014 May 1;171(5):572-81. doi: 10.1176/appi.ajp.2014.13060821. PMID: 24700290Free PMC Article
Yaeger K, Alhilali L, Fakhran S
AJR Am J Roentgenol 2014 Mar;202(3):614-8. doi: 10.2214/AJR.13.11091. PMID: 24555599
Schneider DF, Burke JF, Ojomo KA, Clark N, Mazeh H, Sippel RS, Chen H
Ann Surg Oncol 2013 Dec;20(13):4205-11. Epub 2013 Aug 14 doi: 10.1245/s10434-013-3190-4. [Epub ahead of print] PMID: 23943034
Martin RC, Triebel KL, Kennedy RE, Nicholas AP, Watts RL, Stover NP, Brandon M, Marson DC
Parkinsonism Relat Disord 2013 Nov;19(11):986-90. Epub 2013 Jul 27 doi: 10.1016/j.parkreldis.2013.06.017. [Epub ahead of print] PMID: 23899743
Mascalchi M, Ginestroni A, Bessi V, Toschi N, Padiglioni S, Ciulli S, Tessa C, Giannelli M, Bracco L, Diciotti S
AJNR Am J Neuroradiol 2013 Nov-Dec;34(11):2098-104. Epub 2013 Jun 6 doi: 10.3174/ajnr.A3568. [Epub ahead of print] PMID: 23744687

Therapy

Chen CA, Chen SY, Wang JK, Tseng WY, Chiu HH, Chang CI, Chiu IS, Chen YS, Yang MC, Lu CW, Lin MT, Wu MH
Am Heart J 2014 Apr;167(4):555-61. Epub 2014 Jan 15 doi: 10.1016/j.ahj.2013.12.026. [Epub ahead of print] PMID: 24655705
Mattsson N, Tosun D, Insel PS, Simonson A, Jack CR Jr, Beckett LA, Donohue M, Jagust W, Schuff N, Weiner MW; Alzheimer's Disease Neuroimaging Initiative
Brain 2014 May;137(Pt 5):1550-61. Epub 2014 Mar 12 doi: 10.1093/brain/awu043. [Epub ahead of print] PMID: 24625697Free PMC Article
Babiloni C, Del Percio C, Lizio R, Marzano N, Infarinato F, Soricelli A, Salvatore E, Ferri R, Bonforte C, Tedeschi G, Montella P, Baglieri A, Rodriguez G, Famà F, Nobili F, Vernieri F, Ursini F, Mundi C, Frisoni GB, Rossini PM
Neurobiol Aging 2014 Jan;35(1):130-42. Epub 2013 Jul 30 doi: 10.1016/j.neurobiolaging.2013.06.019. [Epub ahead of print] PMID: 23906617
Wells RE, Yeh GY, Kerr CE, Wolkin J, Davis RB, Tan Y, Spaeth R, Wall RB, Walsh J, Kaptchuk TJ, Press D, Phillips RS, Kong J
Neurosci Lett 2013 Nov 27;556:15-9. Epub 2013 Oct 10 doi: 10.1016/j.neulet.2013.10.001. [Epub ahead of print] PMID: 24120430Free PMC Article
Trzepacz PT, Yu P, Bhamidipati PK, Willis B, Forrester T, Tabas L, Schwarz AJ, Saykin AJ; Alzheimer's Disease Neuroimaging Initiative
Alzheimers Dement 2013 Oct;9(5 Suppl):S95-S104.e1. Epub 2012 Dec 17 doi: 10.1016/j.jalz.2012.10.005. [Epub ahead of print] PMID: 23253778Free PMC Article

Prognosis

Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA
Am J Psychiatry 2014 May 1;171(5):572-81. doi: 10.1176/appi.ajp.2014.13060821. PMID: 24700290Free PMC Article
Mirelman A, Weiss A, Buchman AS, Bennett DA, Giladi N, Hausdorff JM
J Am Geriatr Soc 2014 Apr;62(4):673-8. Epub 2014 Mar 17 doi: 10.1111/jgs.12734. [Epub ahead of print] PMID: 24635699Free PMC Article
Christopher L, Marras C, Duff-Canning S, Koshimori Y, Chen R, Boileau I, Segura B, Monchi O, Lang AE, Rusjan P, Houle S, Strafella AP
Brain 2014 Feb;137(Pt 2):565-75. Epub 2013 Dec 12 doi: 10.1093/brain/awt337. [Epub ahead of print] PMID: 24334314
Schneider DF, Burke JF, Ojomo KA, Clark N, Mazeh H, Sippel RS, Chen H
Ann Surg Oncol 2013 Dec;20(13):4205-11. Epub 2013 Aug 14 doi: 10.1245/s10434-013-3190-4. [Epub ahead of print] PMID: 23943034
Martin RC, Triebel KL, Kennedy RE, Nicholas AP, Watts RL, Stover NP, Brandon M, Marson DC
Parkinsonism Relat Disord 2013 Nov;19(11):986-90. Epub 2013 Jul 27 doi: 10.1016/j.parkreldis.2013.06.017. [Epub ahead of print] PMID: 23899743

Clinical prediction guides

Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA
Am J Psychiatry 2014 May 1;171(5):572-81. doi: 10.1176/appi.ajp.2014.13060821. PMID: 24700290Free PMC Article
Hanganu A, Bedetti C, Degroot C, Mejia-Constain B, Lafontaine AL, Soland V, Chouinard S, Bruneau MA, Mellah S, Belleville S, Monchi O
Brain 2014 Apr;137(Pt 4):1120-9. Epub 2014 Mar 10 doi: 10.1093/brain/awu036. [Epub ahead of print] PMID: 24613932
Yaeger K, Alhilali L, Fakhran S
AJR Am J Roentgenol 2014 Mar;202(3):614-8. doi: 10.2214/AJR.13.11091. PMID: 24555599
Christopher L, Marras C, Duff-Canning S, Koshimori Y, Chen R, Boileau I, Segura B, Monchi O, Lang AE, Rusjan P, Houle S, Strafella AP
Brain 2014 Feb;137(Pt 2):565-75. Epub 2013 Dec 12 doi: 10.1093/brain/awt337. [Epub ahead of print] PMID: 24334314
Martin RC, Triebel KL, Kennedy RE, Nicholas AP, Watts RL, Stover NP, Brandon M, Marson DC
Parkinsonism Relat Disord 2013 Nov;19(11):986-90. Epub 2013 Jul 27 doi: 10.1016/j.parkreldis.2013.06.017. [Epub ahead of print] PMID: 23899743

Recent systematic reviews

Polyakova M, Sonnabend N, Sander C, Mergl R, Schroeter ML, Schroeder J, Schönknecht P
J Affect Disord 2014 Jan;152-154:28-38. Epub 2013 Sep 25 doi: 10.1016/j.jad.2013.09.016. [Epub ahead of print] PMID: 24103852
Forlenza OV, Diniz BS, Teixeira AL, Stella F, Gattaz W
Rev Bras Psiquiatr 2013 Jul-Sep;35(3):284-94. doi: 10.1590/1516-4446-2012-3505. PMID: 24142092
Tricco AC, Soobiah C, Berliner S, Ho JM, Ng CH, Ashoor HM, Chen MH, Hemmelgarn B, Straus SE
CMAJ 2013 Nov 5;185(16):1393-401. Epub 2013 Sep 16 doi: 10.1503/cmaj.130451. [Epub ahead of print] PMID: 24043661Free PMC Article
Schneider DF, Burke JF, Ojomo KA, Clark N, Mazeh H, Sippel RS, Chen H
Ann Surg Oncol 2013 Dec;20(13):4205-11. Epub 2013 Aug 14 doi: 10.1245/s10434-013-3190-4. [Epub ahead of print] PMID: 23943034
Russ TC, Morling JR
Cochrane Database Syst Rev 2012 Sep 12;9:CD009132. doi: 10.1002/14651858.CD009132.pub2. PMID: 22972133

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