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Results: 1 to 20 of 21

1.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system. . It is important to get plenty of calcium in the foods you eat. Foods rich in calcium include dairy products such as milk, cheese and yogurt, and leafy, green vegetables. The exact amount of calcium you need depends on your age and other factors. Growing children and teenagers need more calcium than young adults. Older women need plenty of calcium to prevent osteoporosis. People who do not eat enough high-calcium foods should take a calcium supplement. NIH: National Institutes of Health Office of Dietary Supplements.  [from MedlinePlus]

MedGen UID:
710
Concept ID:
C0006675
Pharmacologic Substance
2.

Calcium channel

Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. [GOC:mtg_transport, GOC:pr, ISBN:0815340729] [from GO]

MedGen UID:
685837
Concept ID:
C1153433
Molecular Function
3.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
4.

Excitability

MedGen UID:
536361
Concept ID:
C0235169
Sign or Symptom
5.

Membrane Transport Modulators

Agents that affect ION PUMPS; ION CHANNELS; ABC TRANSPORTERS; and other MEMBRANE TRANSPORT PROTEINS. [from MeSH]

MedGen UID:
288786
Concept ID:
C1563710
Pharmacologic Substance
6.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
7.

Mibefradil

A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE. [from MeSH]

MedGen UID:
129459
Concept ID:
C0286185
Pharmacologic Substance
8.

Senility

MedGen UID:
115903
Concept ID:
C0231337
Finding
9.

Posicor

MedGen UID:
54852
Concept ID:
C0137970
Pharmacologic Substance
10.

Calcium Channel Blockers

class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools; since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. [from CRISP]

MedGen UID:
14277
Concept ID:
C0006684
Pharmacologic Substance
11.

Naphthalene

A white, volatile, solid polycyclic hydrocarbon with a strong mothball odor. Naphthalene is obtained from either coal tar or petroleum distillation and is primarily used to manufacture phthalic anhydride, but is also used in moth repellents. Exposure to naphthalene is associated with hemolytic anemia, damage to the liver and neurological system, cataracts and retinal hemorrhage. Naphthalene is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing laryngeal and colorectal cancer. (NCI05) [from NCI]

MedGen UID:
10178
Concept ID:
C0027375
Pharmacologic Substance
12.

Down-regulation

A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. [from MeSH]

MedGen UID:
4386
Concept ID:
C0013081
Molecular Function
13.

Cardiovascular Agents

agents that effect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume. [from CRISP]

MedGen UID:
2847
Concept ID:
C0007220
Pharmacologic Substance
14.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from OMIM]

MedGen UID:
1376
Concept ID:
C0001811
15.

neurotrophin 4, rat

MedGen UID:
188000
Concept ID:
C0958894
Pharmacologic Substance
16.

NT-4, human

MedGen UID:
70084
Concept ID:
C0246760
Pharmacologic Substance
17.

NT-4, rat

MedGen UID:
68201
Concept ID:
C0246761
Pharmacologic Substance
18.

neurotrophin 4

MedGen UID:
59344
Concept ID:
C0166894
Pharmacologic Substance
19.

Calcium channel blocker not indicated

MedGen UID:
700319
Concept ID:
C1277237
Finding
20.

Calcium channel blocker indicated

MedGen UID:
700310
Concept ID:
C1277228
Finding

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