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Results: 19

1.

Nitric Oxide

name of an inorganic chemical [from CHV]

MedGen UID:
14378
Concept ID:
C0028128
Pharmacologic Substance
2.

stas-Hustenlser

MedGen UID:
258489
Concept ID:
C1449521
Pharmacologic Substance
3.

enzyme activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [ISBN:0198506732] [from GO]

MedGen UID:
66218
Concept ID:
C0243102
Molecular Function
4.

Threonine

An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins. [from MeSH]

MedGen UID:
52734
Concept ID:
C0040005
Pharmacologic Substance
5.

Shock

Shock happens when your blood pressure is too low and not enough blood and oxygen can get to your organs and tissues. Causes of shock include internal or external bleeding, dehydration, burns, or severe vomiting and/or diarrhea. All of these involve the loss of large amounts of body fluids. Shock often accompanies injury. Specific types of shock include: -Hypovolemic shock, caused by internal or external bleeding. -Septic shock, caused by infections in the bloodstream. -Anaphylactic shock, caused by a severe allergic reaction. -Cardiogenic shock, caused by the inability of the heart to pump blood effectively. -Neurogenic shock, caused by damage to the nervous system. Symptoms of shock include cold and sweaty skin, weak but rapid pulse, irregular breathing, dry mouth, dilated pupils and reduced urine flow. Shock is life threatening and it is important to get help right away. Treatment of shock depends on the cause. National Institute of General Medical Sciences.  [from MedlinePlus]

MedGen UID:
20738
Concept ID:
C0036974
Pathologic Function
6.

Serine

A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04) [from NCI]

MedGen UID:
11382
Concept ID:
C0036720
Pharmacologic Substance
7.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
8.

Amino acid

One of several molecules that join together to form proteins. There are 20 common amino acids found in proteins. [from NCI]

MedGen UID:
250
Concept ID:
C0002520
Pharmacologic Substance
9.

Dephosphorylation

The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. [ISBN:0198506732] [from GO]

MedGen UID:
463624
Concept ID:
C3160734
Molecular Function
10.

Error occurred: cannot get document summary

ID:
431463

11.

Cavernous hemangioma of brain

A disorder characterized by malformations in the structure of the capillaries in the brain. It is caused by mutations in the CCM2, KRIT1 and PDCD10 genes. The capillaries fill with blood and stretch, thereby creating cavernous spaces. Some patients experience headaches, seizures, or visual and hearing disturbances. Cerebral hemorrhage may also occur. [from NCI]

MedGen UID:
418825
Concept ID:
C2919945
Anatomical Abnormality
12.

CATARACT, MARNER TYPE

MedGen UID:
350517
Concept ID:
C1861821
Disease or Syndrome
13.

Cerebral cavernous malformation

Cerebral cavernous malformations (CCMs) are vascular malformations in the brain and spinal cord comprising closely clustered, enlarged capillary channels (caverns) with a single layer of endothelium without mature vessel wall elements or normal intervening brain parenchyma. The diameter of CCMs ranges from a few millimeters to several centimeters. CCMs increase or decrease in size and increase in number over time. Hundreds of lesions may be identified, depending on the person’s age and the quality and type of brain imaging used. Although CCMs have been reported in infants and children, the majority become evident between the second and fifth decades with findings such as seizures, focal neurologic deficits, nonspecific headaches, and cerebral hemorrhage. Up to 50% of individuals with CCM remain symptom free throughout their lives. Familial cerebral cavernous malformation (FCCM) is defined as the occurrence of CCMs in at least two family members and/or the presence of multiple CCMs and/or the presence of a disease-causing mutation in one of the three genes in which mutations are known to cause familial CCM. Cutaneous vascular lesions are found in 9% of those with FCCM and retinal vascular lesions in almost 5%. [from GeneReviews]

MedGen UID:
349362
Concept ID:
C1861784
Disease or Syndrome
14.

Protein dephosphorylation

The process of removing one or more phosphoric residues from a protein. [GOC:hb] [from GO]

MedGen UID:
223888
Concept ID:
C1158884
Molecular Function
15.

Stress

Everyone feels stressed from time to time. Not all stress is bad. All animals have a stress response, and it can be life-saving. But chronic stress can cause both physical and mental harm. There are at least three different types of stress:: -Routine stress related to the pressures of work, family, and other daily responsibilities. -Stress brought about by a sudden negative change, such as losing a job, divorce, or illness. -Traumatic stress, which happens when you are in danger of being seriously hurt or killed. Examples include a major accident, war, assault, or a natural disaster. This type of stress can cause post-traumatic stress disorder (PTSD). Different people may feel stress in different ways. Some people experience digestive symptoms. Others may have headaches, sleeplessness, depressed mood, anger, and irritability. People under chronic stress get more frequent and severe viral infections, such as the flu or common cold. Vaccines, such as the flu shot, are less effective for them. Some people cope with stress more effectively than others. It's important to know your limits when it comes to stress, so you can avoid more serious health effects. NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
20971
Concept ID:
C0038435
Finding
16.

vessel (polysaccharide)

MedGen UID:
56099
Concept ID:
C0148346
Pharmacologic Substance
17.

Protein binding

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. [from MeSH]

MedGen UID:
18704
Concept ID:
C0033618
Molecular Function
18.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system. . It is important to get plenty of calcium in the foods you eat. Foods rich in calcium include dairy products such as milk, cheese and yogurt, and leafy, green vegetables. The exact amount of calcium you need depends on your age and other factors. Growing children and teenagers need more calcium than young adults. Older women need plenty of calcium to prevent osteoporosis. People who do not eat enough high-calcium foods should take a calcium supplement. NIH: National Institutes of Health Office of Dietary Supplements.  [from MedlinePlus]

MedGen UID:
710
Concept ID:
C0006675
Pharmacologic Substance
19.

Blood clotting factor

Endogenous substances, usually proteins, that are involved in the blood coagulation process. [from MeSH]

MedGen UID:
605
Concept ID:
C0005789
Pharmacologic Substance

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