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Results: 7

1.

vessel (polysaccharide)

MedGen UID:
56099
Concept ID:
C0148346
Pharmacologic Substance
2.

tetrathiomolybdate bis-choline salt

MedGen UID:
775625
Concept ID:
C3661426
Pharmacologic Substance
3.

ATN-224

An orally active second generation tetrathiomolybdate analog with anti-angiogenic and antineoplastic activities. ATN-224 selectively chelates the copper ion in superoxide dismutase 1 (SOD1) in endothelial cells, thereby depleting SOD1 of copper and inhibiting its activity. Inhibition of SOD1 interferes with the activation of several signal transduction pathways required for cellular proliferation and angiogenesis, including those mediated by ERK1/2 and FAK and Src kinases. This results in an inhibition of cell proliferation and angiogenesis as well as induction of apoptosis. [from NCI]

MedGen UID:
316868
Concept ID:
C1831930
Pharmacologic Substance
4.

tetrathiomolybdate, disodium salt

MedGen UID:
218684
Concept ID:
C0953058
Pharmacologic Substance
5.

tetrathiomolybdate, dipotassium salt

MedGen UID:
188233
Concept ID:
C0953057
Pharmacologic Substance
6.

thiomolybdate

MedGen UID:
101478
Concept ID:
C0145663
Pharmacologic Substance
7.

Tetrathiomolybdate

MedGen UID:
35368
Concept ID:
C0076339
Pharmacologic Substance

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