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Results: 1 to 20 of 23

1.

Genistein

An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE. [from MeSH]

MedGen UID:
29583
Concept ID:
C0061202
Pharmacologic Substance
2.

Estrogens

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Pharmacologic Substance
3.

Phytoestrogens

PLANT EXTRACTS and compounds, primarily ISOFLAVONES, that mimic or modulate endogenous estrogens, usually by binding to ESTROGEN RECEPTORS. [from MeSH]

MedGen UID:
33114
Concept ID:
C0071011
Pharmacologic Substance
4.

Isoflavones

3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position. [from MeSH]

MedGen UID:
7168
Concept ID:
C0022179
Pharmacologic Substance
5.

Estradiol

a steroid sex hormone [from CHV]

MedGen UID:
4551
Concept ID:
C0014912
Pharmacologic Substance
6.

Bromodeoxyuridine

A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors. [from MeSH]

MedGen UID:
2358
Concept ID:
C0006233
Pharmacologic Substance
7.

Malignant tumor of breast

A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males. [from NCI]

MedGen UID:
651
Concept ID:
C0006142
Neoplastic Process
8.

Aglycone

MedGen UID:
551122
Concept ID:
C0304518
Pharmacologic Substance
9.

Breast carcinoma

The presence of a `carcinoma` (MPATH:549) of the `breast` (FMA:9601). [from HPO]

MedGen UID:
428324
Concept ID:
CN002714
Finding
10.

Neoplasm of breast

Tumors or cancer of the human BREAST. [from MeSH]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
11.

Growth and reproduction of new similar forms, e.g. cells, buds, or offspring. [from NCI]

MedGen UID:
137720
Concept ID:
C0334094
12.

Fish-eye disease

Fish-eye disease, also called partial LCAT deficiency, is a disorder that causes the clear front surface of the eyes (the corneas) to gradually become cloudy. The cloudiness, which generally first appears in adolescence or early adulthood, consists of small grayish dots of cholesterol (opacities) distributed across the corneas. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals; it aids in many functions of the body but can become harmful in excessive amounts. As fish-eye disease progresses, the corneal cloudiness worsens and can lead to severely impaired vision. [from GHR]

MedGen UID:
83354
Concept ID:
C0342895
Disease or Syndrome
13.

Soy protein

Proteins which are present in the edible portion of SOYBEANS. [from MeSH]

MedGen UID:
78279
Concept ID:
C0074926
Pharmacologic Substance
14.

Caseins

principle protein of milk, whose precipitation by calcium is the basis of curdling; used as a nutritional supplement. [from CRISP]

MedGen UID:
794
Concept ID:
C0007332
Pharmacologic Substance
15.

Peptide Biosynthesis

The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. [CHEBI:16670, GOC:dph, GOC:jl] [from GO]

MedGen UID:
272130
Concept ID:
C1327133
Molecular Function
16.

MedGen UID:
108933
Concept ID:
C0597295
17.

Skin and Connective Tissue Diseases

A collective term for diseases of the skin and its appendages and of connective tissue. [from MeSH]

MedGen UID:
59786
Concept ID:
C0175166
Disease or Syndrome
18.

Stimulation, Chemical

The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical. [from MeSH]

MedGen UID:
21327
Concept ID:
C0038337
Molecular Function
19.

Disorder of skin

Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.(NCI) [from NCI]

MedGen UID:
20777
Concept ID:
C0037274
Disease or Syndrome
20.

Neoplasms, Hormone-Dependent

Certain tumors that 1, arise in organs that are normally dependent on specific hormones and 2, are stimulated or caused to regress by manipulation of the endocrine environment. [from MeSH]

MedGen UID:
10218
Concept ID:
C0027661
Neoplastic Process

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