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Mental disorder

MedGen UID:
14047
•Concept ID:
C0004936
•
Mental or Behavioral Dysfunction
Synonym: Mental Disorders
SNOMED CT: Mental disorder (74732009); Mental illness (74732009); Mental disease (74732009); Psychiatric illness (74732009); Psychiatric disorder (74732009); Mental health disorder (74732009)
 
Monarch Initiative: MONDO:0005084

Definition

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Mental disorder

Professional guidelines

PubMed

Management of anorexia nervosa in pregnancy: a systematic and state-of-the-art review.
Galbally M, Himmerich H, Senaratne S, Fitzgerald P, Frost J, Woods N, Dickinson JE
Lancet Psychiatry 2022 May;9(5):402-412. Epub 2022 Mar 24 doi: 10.1016/S2215-0366(22)00031-1. PMID: 35339207
The Diagnosis and Treatment of Enuresis and Functional Daytime Urinary Incontinence.
Gontard AV, Kuwertz-Bröking E
Dtsch Arztebl Int 2019 Apr 19;116(16):279-285. doi: 10.3238/arztebl.2019.0279. PMID: 31159915Free PMC Article
Exercise as a Treatment for Schizophrenia: A Review.
Girdler SJ, Confino JE, Woesner ME
Psychopharmacol Bull 2019 Feb 15;49(1):56-69. PMID: 30858639Free PMC Article

Recent clinical studies

Etiology

Overall and Cervical Cancer Survival in Patients With and Without Mental Disorders.
Herweijer E, Wang J, Hu K, Valdimarsdóttir UA, Adami HO, Sparén P, Sundström K, Fang F
JAMA Netw Open 2023 Sep 5;6(9):e2336213. doi: 10.1001/jamanetworkopen.2023.36213. PMID: 37773493Free PMC Article
Mental disorder and opioid overdose: a systematic review.
van Draanen J, Tsang C, Mitra S, Phuong V, Murakami A, Karamouzian M, Richardson L
Soc Psychiatry Psychiatr Epidemiol 2022 Apr;57(4):647-671. Epub 2021 Nov 18 doi: 10.1007/s00127-021-02199-2. PMID: 34796369Free PMC Article
Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Diagnostic Issues and Controversies in DSM-5: Return of the False Positives Problem.
Wakefield JC
Annu Rev Clin Psychol 2016;12:105-32. Epub 2016 Jan 11 doi: 10.1146/annurev-clinpsy-032814-112800. PMID: 26772207

Diagnosis

What is a mental disorder? An exemplar-focused approach.
Stein DJ, Palk AC, Kendler KS
Psychol Med 2021 Apr;51(6):894-901. Epub 2021 Apr 12 doi: 10.1017/S0033291721001185. PMID: 33843505Free PMC Article
Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Diagnostic Issues and Controversies in DSM-5: Return of the False Positives Problem.
Wakefield JC
Annu Rev Clin Psychol 2016;12:105-32. Epub 2016 Jan 11 doi: 10.1146/annurev-clinpsy-032814-112800. PMID: 26772207
The global prevalence of common mental disorders: a systematic review and meta-analysis 1980-2013.
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article

Therapy

Lamotrigine in the maintenance treatment of bipolar disorder.
Hashimoto Y, Kotake K, Watanabe N, Fujiwara T, Sakamoto S
Cochrane Database Syst Rev 2021 Sep 15;9(9):CD013575. doi: 10.1002/14651858.CD013575.pub2. PMID: 34523118Free PMC Article
Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial).
Jacka FN, O'Neil A, Opie R, Itsiopoulos C, Cotton S, Mohebbi M, Castle D, Dash S, Mihalopoulos C, Chatterton ML, Brazionis L, Dean OM, Hodge AM, Berk M
BMC Med 2017 Jan 30;15(1):23. doi: 10.1186/s12916-017-0791-y. PMID: 28137247Free PMC Article
The global prevalence of common mental disorders: a systematic review and meta-analysis 1980-2013.
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article
The biomedical model of mental disorder: a critical analysis of its validity, utility, and effects on psychotherapy research.
Deacon BJ
Clin Psychol Rev 2013 Nov;33(7):846-61. Epub 2013 Apr 8 doi: 10.1016/j.cpr.2012.09.007. PMID: 23664634

Prognosis

Incidence Rates and Cumulative Incidences of the Full Spectrum of Diagnosed Mental Disorders in Childhood and Adolescence.
Dalsgaard S, Thorsteinsson E, Trabjerg BB, Schullehner J, Plana-Ripoll O, Brikell I, Wimberley T, Thygesen M, Madsen KB, Timmerman A, Schendel D, McGrath JJ, Mortensen PB, Pedersen CB
JAMA Psychiatry 2020 Feb 1;77(2):155-164. doi: 10.1001/jamapsychiatry.2019.3523. PMID: 31746968Free PMC Article
Prediction of major depressive disorder onset in college students.
Ebert DD, Buntrock C, Mortier P, Auerbach R, Weisel KK, Kessler RC, Cuijpers P, Green JG, Kiekens G, Nock MK, Demyttenaere K, Bruffaerts R
Depress Anxiety 2019 Apr;36(4):294-304. Epub 2018 Dec 6 doi: 10.1002/da.22867. PMID: 30521136Free PMC Article
A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders.
Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ, Mortensen PB, Eaton WW
JAMA Psychiatry 2014 May;71(5):573-81. doi: 10.1001/jamapsychiatry.2014.16. PMID: 24806211
No health without mental health.
Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A
Lancet 2007 Sep 8;370(9590):859-77. doi: 10.1016/S0140-6736(07)61238-0. PMID: 17804063
Schizophrenia and violence.
Angermeyer MC
Acta Psychiatr Scand Suppl 2000;(407):63-7. doi: 10.1034/j.1600-0447.2000.00012.x. PMID: 11261644

Clinical prediction guides

Psychosocial function, legal involvement and violence in mental disorder.
Buchanan A, Moore KE, Pittman B, McKee SA
Eur Psychiatry 2021 Dec 3;64(1):e75. doi: 10.1192/j.eurpsy.2021.2250. PMID: 34859762Free PMC Article
Mental disorder and PTSD in Syria during wartime: a nationwide crisis.
Kakaje A, Al Zohbi R, Hosam Aldeen O, Makki L, Alyousbashi A, Alhaffar MBA
BMC Psychiatry 2021 Jan 2;21(1):2. doi: 10.1186/s12888-020-03002-3. PMID: 33388026Free PMC Article
Measurement and mental health disparities: Psychopathology classification and identity assessment.
Eaton NR
Personal Ment Health 2020 Feb;14(1):76-87. Epub 2019 Jun 20 doi: 10.1002/pmh.1449. PMID: 31219231
Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H
Nutrients 2019 Oct 3;11(10) doi: 10.3390/nu11102362. PMID: 31623400Free PMC Article
Subtypes of firesetters.
Dalhuisen L, Koenraadt F, Liem M
Crim Behav Ment Health 2017 Feb;27(1):59-75. Epub 2015 Nov 25 doi: 10.1002/cbm.1984. PMID: 26602887

Recent systematic reviews

Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies.
Lane MM, Gamage E, Travica N, Dissanayaka T, Ashtree DN, Gauci S, Lotfaliany M, O'Neil A, Jacka FN, Marx W
Nutrients 2022 Jun 21;14(13) doi: 10.3390/nu14132568. PMID: 35807749Free PMC Article
Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic.
COVID-19 Mental Disorders Collaborators
Lancet 2021 Nov 6;398(10312):1700-1712. Epub 2021 Oct 8 doi: 10.1016/S0140-6736(21)02143-7. PMID: 34634250Free PMC Article
Impact of COVID-19 on Mental Health in Adolescents: A Systematic Review.
Jones EAK, Mitra AK, Bhuiyan AR
Int J Environ Res Public Health 2021 Mar 3;18(5) doi: 10.3390/ijerph18052470. PMID: 33802278Free PMC Article
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268

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