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GTP Phosphohydrolase Activators

MedGen UID:
199779
Concept ID:
C0751976
Pharmacologic Substance
Synonyms: Activators, GTP Phosphohydrolase; Activators, GTPase; GTPase Activators
 

Definition

Agents and factors that activate GTP phosphohydrolase activity. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGGTP Phosphohydrolase Activators

Recent clinical studies

Etiology

Park SE, Kim JM, Seok OH, Cho H, Wadas B, Kim SY, Varshavsky A, Hwang CS
Science 2015 Mar 13;347(6227):1249-52. doi: 10.1126/science.aaa3844. PMID: 25766235
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Am J Respir Crit Care Med 2015 Mar 1;191(5):574-83. doi: 10.1164/rccm.201407-1341OC. PMID: 25608002
Machida K, Feldman DE, Tsukamoto H
Adv Exp Med Biol 2015;815:131-44. doi: 10.1007/978-3-319-09614-8_8. PMID: 25427905
Holck S, Nielsen HJ, Hammer E, Christensen IJ, Larsson LI
Cancer Lett 2015 Jan 28;356(2 Pt B):556-60. Epub 2014 Oct 8 doi: 10.1016/j.canlet.2014.10.005. [Epub ahead of print] PMID: 25305455
Che MM, Nie Z, Randazzo PA
Methods Enzymol 2005;404:147-63. doi: 10.1016/S0076-6879(05)04015-2. PMID: 16413266

Diagnosis

Zhang T, Shen Y, Chen Y, Hsieh JT, Kong Z
Int J Radiat Biol 2015 Apr;91(4):368-78. Epub 2015 Feb 6 doi: 10.3109/09553002.2015.1001531. [Epub ahead of print] PMID: 25585815
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Cell Mol Life Sci 2015 Apr;72(8):1585-97. Epub 2014 Oct 22 doi: 10.1007/s00018-014-1765-2. [Epub ahead of print] PMID: 25336152
Gremer L, Gilsbach B, Ahmadian MR, Wittinghofer A
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Therapy

Holck S, Nielsen HJ, Hammer E, Christensen IJ, Larsson LI
Cancer Lett 2015 Jan 28;356(2 Pt B):556-60. Epub 2014 Oct 8 doi: 10.1016/j.canlet.2014.10.005. [Epub ahead of print] PMID: 25305455
Davis CT, Zhu W, Gibson CC, Bowman-Kirigin JA, Sorensen L, Ling J, Sun H, Navankasattusas S, Li DY
J Immunol 2014 Jun 15;192(12):6045-52. Epub 2014 May 16 doi: 10.4049/jimmunol.1400309. [Epub ahead of print] PMID: 24835390Free PMC Article
Kim WJ, Lim MN, Hong Y, Silverman EK, Lee JH, Jung BH, Ra SW, Choi HS, Jung YJ, Park YB, Park MJ, Lee SW, Lee JS, Oh YM, Lee SD
Lung 2014 Aug;192(4):473-80. Epub 2014 Apr 16 doi: 10.1007/s00408-014-9579-4. [Epub ahead of print] PMID: 24737086
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Park HO, Chant J, Herskowitz I
Nature 1993 Sep 16;365(6443):269-74. doi: 10.1038/365269a0. PMID: 8371782

Prognosis

Ha YJ, Kim CW, Roh SA, Cho DH, Park JL, Kim SY, Kim JH, Choi EK, Kim YS, Kim JC
Int J Radiat Oncol Biol Phys 2015 Mar 1;91(3):650-8. Epub 2015 Jan 30 doi: 10.1016/j.ijrobp.2014.11.013. [Epub ahead of print] PMID: 25680604
Bisserier M, Berthouze-Duquesnes M, Breckler M, Tortosa F, Fazal L, de Régibus A, Laurent AC, Varin A, Lucas A, Branchereau M, Marck P, Schickel JN, Deloménie C, Cazorla O, Soulas-Sprauel P, Crozatier B, Morel E, Heymes C, Lezoualc'h F
Circulation 2015 Jan 27;131(4):390-400; discussion 400. Epub 2014 Nov 4 doi: 10.1161/CIRCULATIONAHA.114.010686. [Epub ahead of print] PMID: 25369805
Holck S, Nielsen HJ, Hammer E, Christensen IJ, Larsson LI
Cancer Lett 2015 Jan 28;356(2 Pt B):556-60. Epub 2014 Oct 8 doi: 10.1016/j.canlet.2014.10.005. [Epub ahead of print] PMID: 25305455
Raedler D, Ballenberger N, Klucker E, Böck A, Otto R, Prazeres da Costa O, Holst O, Illig T, Buch T, von Mutius E, Schaub B
J Allergy Clin Immunol 2015 Jan;135(1):81-91. Epub 2014 Sep 13 doi: 10.1016/j.jaci.2014.07.046. [Epub ahead of print] PMID: 25226851
Li N, Li S
Biochem Biophys Res Commun 2014 Dec 12;455(3-4):358-62. Epub 2014 Nov 15 doi: 10.1016/j.bbrc.2014.11.020. [Epub ahead of print] PMID: 25446096

Clinical prediction guides

Navarro A, Perez RE, Rezaiekhaligh MH, Mabry SM, Ekekezie II
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Bahou WF, Campbell AD, Wicha MS
J Biol Chem 1992 Jul 15;267(20):13986-92. PMID: 1629197

Recent systematic reviews

Yi SM, Li GY
Tumour Biol 2014 Jan;35(1):441-5. Epub 2013 Sep 5 doi: 10.1007/s13277-013-1061-z. [Epub ahead of print] PMID: 24006220
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J; Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC
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Shiba Y, Randazzo PA
Histol Histopathol 2012 Sep;27(9):1143-53. PMID: 22806901
Smits M, van Rijn S, Hulleman E, Biesmans D, van Vuurden DG, Kool M, Haberler C, Aronica E, Vandertop WP, Noske DP, Würdinger T
Clin Cancer Res 2012 Aug 1;18(15):4048-58. Epub 2012 Jun 13 doi: 10.1158/1078-0432.CCR-12-0399. [Epub ahead of print] PMID: 22696229
Yoon D, Kim YJ, Cui WY, Van der Vaart A, Cho YS, Lee JY, Ma JZ, Payne TJ, Li MD, Park T
Hum Genet 2012 Jun;131(6):1009-21. Epub 2011 Oct 18 doi: 10.1007/s00439-011-1102-x. [Epub ahead of print] PMID: 22006218Free PMC Article

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