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Results: 1 to 20 of 22

1.

Recurrence (disease attribute)

The return of a sign, symptom, or disease after a remission. [from MeSH]

MedGen UID:
416712
Concept ID:
C2825055
Pathologic Function
2.

Formalin

A saturated solution of formaldehyde, water, and typically another agent, most commonly methanol. In its typical form, formalin is 37% formaldehyde by weight (40% by volume), 6-13% methanol, and the rest water. [from NCI]

MedGen UID:
215328
Concept ID:
C0949307
Pharmacologic Substance
3.

SHORT STATURE, ONYCHODYSPLASIA, FACIAL DYSMORPHISM, AND HYPOTRICHOSIS SYNDROME

MedGen UID:
762199
Concept ID:
C3542022
Disease or Syndrome
4.

Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

SOFT syndrome is characterized by severely short long bones, peculiar facies associated with paucity of hair, and nail anomalies. Growth retardation is evident on prenatal ultrasound as early as the second trimester of pregnancy, and affected individuals reach a final stature consistent with a height age of 6 years to 8 years. Relative macrocephaly is present during early childhood but head circumference is markedly low by adulthood. Psychomotor development is normal. Facial dysmorphism includes a long, triangular face with prominent nose and small ears, and affected individuals have an unusual high-pitched voice. Clinodactyly, brachydactyly, and hypoplastic distal phalanges and fingernails are present in association with postpubertal sparse and short hair. Typical skeletal findings include short and thick long bones with mild irregular metaphyseal changes, short femoral necks, and hypoplastic pelvis and sacrum. All long bones of the hand are short, with major delay of carpal ossification and cone-shaped epiphyses. Vertebral body ossification is also delayed (summary by Sarig et al., 2012). [from OMIM]

MedGen UID:
472512
Concept ID:
CN143712
Disease or Syndrome
5.

metaplastic cell transformation

The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal and divides indefinitely. Transformed cells no longer retain cell-cycle checkpoints and may ultimately become malignant cancer cells via additional genetic mutations, or damaging environmental events. [from NCI]

MedGen UID:
266929
Concept ID:
C1510411
Pathologic Function
6.

Aggressive Clinical Course

MedGen UID:
233968
Concept ID:
C1332223
Finding
7.

Inflammatory Infiltrate

MedGen UID:
233553
Concept ID:
C1334178
Finding
8.

The condition of being irregular or not conforming to type. [from NCI]

MedGen UID:
152855
Concept ID:
C0741302
9.

Aggressive behavior

MedGen UID:
98408
Concept ID:
C0424323
Finding
10.

Cytologic atypia

MedGen UID:
90720
Concept ID:
C0333865
Cell or Molecular Dysfunction
11.

Inflammation

A microscopic finding indicating the presence of acute, subacute or chronic inflammation in a tissue sample. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
12.

Aggressive behavior

Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. [from MeSH]

MedGen UID:
1375
Concept ID:
C0001807
Mental or Behavioral Dysfunction
13.

The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. [from MeSH]

MedGen UID:
154544
Concept ID:
C0596263
14.

Plasma cell granuloma

A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells. [from MeSH]

MedGen UID:
42293
Concept ID:
C0018199
Pathologic Function
15.

Neoplastic Processes

The pathological mechanisms and forms taken by tissue during degeneration into a neoplasm and its subsequent activity. [from MeSH]

MedGen UID:
14325
Concept ID:
C0027671
Neoplastic Process
16.

Neoplasm Recurrence, Local

The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site. [from MeSH]

MedGen UID:
10211
Concept ID:
C0027643
Neoplastic Process
17.

Granuloma

small lump caused by inflammation [from CHV]

MedGen UID:
5376
Concept ID:
C0018188
Pathologic Function
18.

Neoplastic Cell Transformation

A pathologic process that involves the transformation of normal cells to a neoplastic state and resulting in polyclonal or monoclonal neoplastic cell proliferation. [from NCI]

MedGen UID:
3302
Concept ID:
C0007621
Neoplastic Process
19.

Chromosome Aberrations

irregularity in the number or structure of chromosomes that may alter the course of development. [from CRISP]

MedGen UID:
954
Concept ID:
C0008625
Cell or Molecular Dysfunction
20.

Aneuploidy

The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1). [from MeSH]

MedGen UID:
294
Concept ID:
C0002938
Cell or Molecular Dysfunction

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