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Vacuolar Protein Sorting

MedGen UID:
275569
Concept ID:
C1519906
Molecular Function
Synonyms: VPS
 

Definition

The process of directing proteins towards the vacuole, usually using signals contained within the protein. [GOC:curators] [from GO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGVacuolar Protein Sorting

Recent clinical studies

Etiology

Zhang Y, Chen S, Xiao Q, Cao L, Liu J, Rong TY, Ma JF, Wang G, Wang Y, Chen SD
Parkinsonism Relat Disord 2012 Jun;18(5):638-40. Epub 2012 Mar 10 doi: 10.1016/j.parkreldis.2012.02.011. [Epub ahead of print] PMID: 22410496
Jounai N, Kobiyama K, Shiina M, Ogata K, Ishii KJ, Takeshita F
J Immunol 2011 Feb 1;186(3):1646-55. Epub 2011 Jan 5 doi: 10.4049/jimmunol.1001654. [Epub ahead of print] PMID: 21209283
Xu L, Sowa ME, Chen J, Li X, Gygi SP, Harper JW
Mol Biol Cell 2008 Dec;19(12):5059-71. Epub 2008 Sep 17 doi: 10.1091/mbc.E08-05-0473. [Epub ahead of print] PMID: 18799622Free PMC Article
Riemenschneider M, Schoepfer-Wendels A, Friedrich P, Konta L, Laws SM, Mueller JC, Kurz A, Förstl H
Neurobiol Aging 2007 Jun;28(6):883-4. Epub 2006 Jun 19 doi: 10.1016/j.neurobiolaging.2006.05.009. [Epub ahead of print] PMID: 16784798
Yamazaki H, Bujo H, Saito Y
J Atheroscler Thromb 1997;4(1):20-6. PMID: 9583350

Diagnosis

Fields J, Dumaop W, Adame A, Ellis RJ, Letendre S, Grant I, Masliah E
J Neuroimmune Pharmacol 2013 Dec;8(5):1197-209. Epub 2013 Nov 30 doi: 10.1007/s11481-013-9511-3. [Epub ahead of print] PMID: 24292993Free PMC Article
Nuytemans K, Bademci G, Inchausti V, Dressen A, Kinnamon DD, Mehta A, Wang L, Züchner S, Beecham GW, Martin ER, Scott WK, Vance JM
Neurology 2013 Mar 12;80(11):982-9. Epub 2013 Feb 13 doi: 10.1212/WNL.0b013e31828727d4. [Epub ahead of print] PMID: 23408866Free PMC Article
Chen Y, Chen K, Song W, Chen X, Cao B, Huang R, Zhao B, Guo X, Burgunder J, Li J, Shang HF
Neurobiol Aging 2013 Jun;34(6):1709.e7-8. Epub 2012 Dec 20 doi: 10.1016/j.neurobiolaging.2012.11.003. [Epub ahead of print] PMID: 23261770
Idiris A, Tohda H, Sasaki M, Okada K, Kumagai H, Giga-Hama Y, Takegawa K
Appl Microbiol Biotechnol 2010 Jan;85(3):667-77. Epub 2009 Aug 11 doi: 10.1007/s00253-009-2151-0. [Epub ahead of print] PMID: 19669754
Martin-Serrano J, Eastman SW, Chung W, Bieniasz PD
J Cell Biol 2005 Jan 3;168(1):89-101. Epub 2004 Dec 28 doi: 10.1083/jcb.200408155. [Epub ahead of print] PMID: 15623582Free PMC Article

Therapy

Nuytemans K, Bademci G, Inchausti V, Dressen A, Kinnamon DD, Mehta A, Wang L, Züchner S, Beecham GW, Martin ER, Scott WK, Vance JM
Neurology 2013 Mar 12;80(11):982-9. Epub 2013 Feb 13 doi: 10.1212/WNL.0b013e31828727d4. [Epub ahead of print] PMID: 23408866Free PMC Article
Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Bertram L, Bozi M, Barcikowska M, Crosiers D, Clarke CE, Facheris MF, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon BS, Jamrozik Z, Krygowska-Wajs A, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Libioulle C, Murata M, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Meitnger T, Zimprich A, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Strom TM, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Van Broeckhoven C, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yomono HS, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEOPD consortium
J Med Genet 2012 Nov;49(11):721-6. doi: 10.1136/jmedgenet-2012-101155. PMID: 23125461Free PMC Article
Lazert C, Chazal N, Briant L, Gerlier D, Cortay JC
Retrovirology 2008 May 13;5:39. doi: 10.1186/1742-4690-5-39. [Epub ahead of print] PMID: 18477395Free PMC Article

Prognosis

Fields J, Dumaop W, Adame A, Ellis RJ, Letendre S, Grant I, Masliah E
J Neuroimmune Pharmacol 2013 Dec;8(5):1197-209. Epub 2013 Nov 30 doi: 10.1007/s11481-013-9511-3. [Epub ahead of print] PMID: 24292993Free PMC Article
Liu Y, Lv L, Xue Q, Wan C, Ni T, Chen B, Liu Y, Zhou Y, Ni R, Mao G
Mol Cell Biochem 2013 Sep;381(1-2):163-71. Epub 2013 Jun 5 doi: 10.1007/s11010-013-1699-2. [Epub ahead of print] PMID: 23737133
Smith H, Galmes R, Gogolina E, Straatman-Iwanowska A, Reay K, Banushi B, Bruce CK, Cullinane AR, Romero R, Chang R, Ackermann O, Baumann C, Cangul H, Cakmak Celik F, Aygun C, Coward R, Dionisi-Vici C, Sibbles B, Inward C, Kim CA, Klumperman J, Knisely AS, Watson SP, Gissen P
Hum Mutat 2012 Dec;33(12):1656-64. Epub 2012 Aug 6 doi: 10.1002/humu.22155. [Epub ahead of print] PMID: 22753090Free PMC Article
Sheerin UM, Charlesworth G, Bras J, Guerreiro R, Bhatia K, Foltynie T, Limousin P, Silveira-Moriyama L, Lees A, Wood N
Neurobiol Aging 2012 Apr;33(4):838.e1-5. Epub 2011 Dec 7 doi: 10.1016/j.neurobiolaging.2011.10.032. [Epub ahead of print] PMID: 22154191Free PMC Article
Samaranayake HS, Cowan AE, Klobutcher LA
Eukaryot Cell 2011 Sep;10(9):1207-18. Epub 2011 Jul 15 doi: 10.1128/EC.05089-11. [Epub ahead of print] PMID: 21764909Free PMC Article

Clinical prediction guides

An CH, Kim YR, Kim HS, Kim SS, Yoo NJ, Lee SH
Hum Pathol 2012 Jan;43(1):40-7. Epub 2011 Jul 5 doi: 10.1016/j.humpath.2010.03.015. [Epub ahead of print] PMID: 21733561
Samaranayake HS, Cowan AE, Klobutcher LA
Eukaryot Cell 2011 Sep;10(9):1207-18. Epub 2011 Jul 15 doi: 10.1128/EC.05089-11. [Epub ahead of print] PMID: 21764909Free PMC Article
Yoon J, Aishan T, Maruyama J, Kitamoto K
Appl Environ Microbiol 2010 Sep;76(17):5718-27. Epub 2010 Jul 9 doi: 10.1128/AEM.03087-09. [Epub ahead of print] PMID: 20622126Free PMC Article
Kolesnikova L, Strecker T, Morita E, Zielecki F, Mittler E, Crump C, Becker S
J Virol 2009 Mar;83(5):2327-37. Epub 2008 Dec 17 doi: 10.1128/JVI.02184-08. [Epub ahead of print] PMID: 19091859Free PMC Article
Garrus JE, von Schwedler UK, Pornillos OW, Morham SG, Zavitz KH, Wang HE, Wettstein DA, Stray KM, Côté M, Rich RL, Myszka DG, Sundquist WI
Cell 2001 Oct 5;107(1):55-65. PMID: 11595185

Recent systematic reviews

Kang JH, Ryu HS, Kim HT, Lee SJ, Choi UK, Park YB, Huh TL, Choi MS, Kang TC, Choi SY, Kwon OS
Biochim Biophys Acta 2009 Mar;1794(3):446-58. Epub 2008 Dec 6 doi: 10.1016/j.bbapap.2008.11.015. [Epub ahead of print] PMID: 19103313

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